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Full-Text Articles in Psychology
The Effect Of Chronic Ethanol On Vta Gaba Neurons, Stephanie Bair, Scott Steffensen
The Effect Of Chronic Ethanol On Vta Gaba Neurons, Stephanie Bair, Scott Steffensen
Journal of Undergraduate Research
The current accepted model for addiction in the brain is the dysregulation of dopamine (DA) in the mesolimbic pathway, which begins in the ventral tegmental area (VTA) and projects to the nucleus accumbens (NAc). DA neurons originate in the VTA and project to the NAc where they release DA. Dopamine neurons are typically regulated locally by inhibitory gamma-aminobutyric acid (GABA) neurons in the VTA. Because GABA neurons in the VTA regulate DA neurons, we conclude that changes in VTA GABA neurons will affect DA release in the NAc underlying addictive behaviors, especially reward seeking.
The Effects Of Chronic Ethanol In Δ Knockout Mice, Zachary Gardner, Scott Steffensen
The Effects Of Chronic Ethanol In Δ Knockout Mice, Zachary Gardner, Scott Steffensen
Journal of Undergraduate Research
Substance abuse is a prolific problem with serious consequences. Specifically, alcohol abuse is the third leading cause of preventable mortality in the world (Mokdad et al., 2004). Each year the far-reaching effects of alcohol abuse cost the United States several hundred billion dollars annually (Office of National Policy, 2004). Treatment for individuals who suffer from this crippling disease is limited. In order to develop effective treatments we need to know more about the mechanisms of addiction and the changes that occur in the brain as a person becomes addicted.
The Effects Of Chronic Ethanol In Δ Knockout Mice, Zachary Gardner, Scott Steffensen
The Effects Of Chronic Ethanol In Δ Knockout Mice, Zachary Gardner, Scott Steffensen
Journal of Undergraduate Research
Substance abuse is a prolific problem with serious consequences. Specifically, alcohol abuse is the third leading cause of preventable mortality in the world (Mokdad et al., 2004). Each year the far-reaching effects of alcohol abuse cost the United States several hundred billion dollars annually (Office of National Policy, 2004). Treatment for individuals who suffer from this crippling disease is limited. In order to develop effective treatments we need to know more about the mechanisms of addiction and the changes that occur in the brain as a person becomes addicted.
Effects Of Chronic Ethanol On Gaba(A) Receptors In The Vta, Ashley Nelson, Dr. Scot Steffensen
Effects Of Chronic Ethanol On Gaba(A) Receptors In The Vta, Ashley Nelson, Dr. Scot Steffensen
Journal of Undergraduate Research
The Centers for Disease Control and Prevention attributes approximately 80,000 deaths annually to excessive alcohol use (CDC), and alcohol consumption is the third leading cause of preventable deaths in the United States (Mokdad et al., 2004). These statistics do not even describe the detrimental effects alcohol addiction has on personal lives and families. The accepted model for addiction in the brain is a change in the normal regulation of the neurotransmitter dopamine (DA) in the mesolimbic pathway. Studying this pathway is important in developing treatments for addiction, which has implications to improve the lives of many suffering people. The primary …