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Full-Text Articles in Psychology
Aging And Pattern Separation, Nathan Giles, Dr. C. Brock Kirwan
Aging And Pattern Separation, Nathan Giles, Dr. C. Brock Kirwan
Journal of Undergraduate Research
It is widely known that as we age, our cognitive functions start to decrease, especially when it comes to memory. Memory in the human brain has major processes in the medial temporal lobe, specifically the hippocampus. It is widely accepted that in older adults, the areas in the medial temporal lobe start to atrophy and this decrease in brain tissue volume is what leads to difficulty in memory (Van Petten, 2004). Further, as we age the rate of new neuron growth (termed neurogenesis) in the dentate gyrus region of the hippocampus slows down (Small, 2001). Neurogenesis in the dentate gyrus …
Change Over Time Of White Matter Hyperintensities And Cognitive Scores In The Cache County Memory And Aging Study, Zachary Mcdonnell, Dr. Erin Bigler
Change Over Time Of White Matter Hyperintensities And Cognitive Scores In The Cache County Memory And Aging Study, Zachary Mcdonnell, Dr. Erin Bigler
Journal of Undergraduate Research
The Cache County Study on Memory in Aging (CCMA) includes a sample of over 400 individuals with magnetic resonance imaging (MRI) (Bigler et al., 2000). Studies have shown that White Matter Hyperintensities (WMH) on MRIs are associated with not only cognitive decline, but degenerative disorders like Alzheimer’s disease (Philip Scheltens et al., 1998). A common and widely used clinical rating method for identifying WMH is the Scheltens Rating Scale (PH Scheltens et al., 1993). This scale rates WMH, Grey Matter Hyperintensities (GMH), Periventricular White Matter Hyperintensities (PWM), and Infratentorial Signal Hyperintensites (IFH) in a semi-quantitative scale that can be easily …