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The Effects Of Genes On The Stress Response, S. Andrew Aston
The Effects Of Genes On The Stress Response, S. Andrew Aston
Journal of Undergraduate Research
Corticotropin-releasing hormone (CRH) acts as one of the primary coordinators of the physiological, behavioral, and autonomic stress response. CRH secreted from the paraventricular nucleus (PVN) of the hypothalamus initiates the hypothalamic pituitary adrenal (HPA) axis response by signaling the secretion of adrenocorticotropic hormone (ACTH) from the anterior pituitary. ACTH then travels to the adrenal glands, leading to the release of cortisol Thus, CRH plays a key role in preparing an individual to adaptively respond to a stressful situation.