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Augsburg University

Generalization

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Underlying Mechanisms Of Generalized Anxiety Disorder In An Experimental Fear-Conditioning Paradigm, Melissa Hartnell Nov 2023

Underlying Mechanisms Of Generalized Anxiety Disorder In An Experimental Fear-Conditioning Paradigm, Melissa Hartnell

Theses and Graduate Projects

The purpose of this study was to examine the potential underlying mechanisms of generalized anxiety disorder (GAD) including fear generalization, maladaptive avoidance, and intolerance of uncertainty (IU) in a sample of adults with GAD, as compared to healthy controls in the context of a lab-based fear conditioning paradigm. The current study utilized data from the University of Minnesota ANGST Laboratory’s Danger Zone – Research Domain Criteria (DZ-RDoC) neuroimaging study. Participants consisted of 40 individuals ranging from ages 18-60, with 19 meeting criteria for GAD (M age = 30.57, SD = 11.70) and 21 healthy controls (M age = …