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Articles 1 - 12 of 12
Full-Text Articles in Psychology
Language Abilities As A Function Of Lateralization Of Language-Specific Brain Networks, Jacey Anderson
Language Abilities As A Function Of Lateralization Of Language-Specific Brain Networks, Jacey Anderson
Honors Scholar Theses
The strength of hemispheric lateralization appears to be a good predictor of language abilities in children with developmental language impairments. Studies of healthy adults, in contrast, have generally failed to identify any association between degree of lateralization and language abilities, perhaps due to limited sensitivity to individual differences in standardized language assessments. This study used fMRI to measure the lateralization of functional task-engaged language networks in 25 healthy right-handed adults. Linear regressions examined lateralization indices (LI) of language activation in inferior temporal, superior temporal, and frontal brain networks, as a function of syntactic complexity (via story retelling), a grammaticality judgment …
Repetition Of Computer Security Warnings Results In Differential Repetition Suppression Effects As Revealed With Functional Mri, C. Brock Kirwan, Daniel K. Bjornn, Bonnie Brinton Anderson, Anthony Vance, David Eargle, Jeffrey L. Jenkins
Repetition Of Computer Security Warnings Results In Differential Repetition Suppression Effects As Revealed With Functional Mri, C. Brock Kirwan, Daniel K. Bjornn, Bonnie Brinton Anderson, Anthony Vance, David Eargle, Jeffrey L. Jenkins
Faculty Publications
Computer users are often the last line of defense in computer security. However, with repeated exposures to system messages and computer security warnings, neural and behavioral responses show evidence of habituation. Habituation has been demonstrated at a neural level as repetition suppression where responses are attenuated with subsequent repetitions. In the brain, repetition suppression to visual stimuli has been demonstrated in multiple cortical areas, including the occipital lobe and medial temporal lobe. Prior research into the repetition suppression effect has generally focused on a single repetition and has not examined the pattern of signal suppression with repeated exposures. We used …
Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder, Carissa Weis
Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder, Carissa Weis
Theses and Dissertations
Posttraumatic stress disorder (PTSD) is a heterogenous psychological disorder that may result from exposure to a traumatic event. Using functional magnetic resonance imaging (fMRI), symptoms of PTSD have been associated with aberrations in brain networks that emerge in the absence of a given cognitive demand or task, called resting state networks. Most previous research in resting state networks and PTSD has focused on aberrations in the static functional connectivity among specific regions of interest (ROI) in the brain and within canonical networks constrained by a priori hypotheses. However, dynamic fMRI, an approach that examines changes in brain network characteristics over …
Structure Of Population Activity In Primary Motor Cortex For Single Finger Flexion And Extension, Spencer A. Arbuckle, Jeff Weiler, Eric A. Kirk, Charles L. Rice, Marc Schieber, J. Andrew Pruszynski, Naveed Ejaz, Jörn Diedrichsen
Structure Of Population Activity In Primary Motor Cortex For Single Finger Flexion And Extension, Spencer A. Arbuckle, Jeff Weiler, Eric A. Kirk, Charles L. Rice, Marc Schieber, J. Andrew Pruszynski, Naveed Ejaz, Jörn Diedrichsen
Brain and Mind Institute Researchers' Publications
Copyright © 2020 the authors How is the primary motor cortex (M1) organized to control fine finger movements? We investigated the population activity in M1 for single finger flexion and extension, using 7T functional magnetic resonance imaging (fMRI) in female and male human participants and compared these results to the neural spiking patterns recorded in two male monkeys performing the identical task. fMRI activity patterns were distinct for movements of different fingers, but were quite similar for flexion and extension of the same finger. In contrast, spiking patterns in monkeys were quite distinct for both fingers and directions, which is …
The Neural Basis Of Metacognitive Monitoring During Arithmetic In The Developing Brain, Elien Bellon, Wim Fias, Daniel Ansari, Bert De Smedt
The Neural Basis Of Metacognitive Monitoring During Arithmetic In The Developing Brain, Elien Bellon, Wim Fias, Daniel Ansari, Bert De Smedt
Brain and Mind Institute Researchers' Publications
In contrast to a substantial body of research on the neural basis of cognitive performance in several academic domains, less is known about how the brain generates metacognitive (MC) awareness of such performance. The existing work on the neurobiological underpinnings of metacognition has almost exclusively been done in adults and has largely focused on lower level cognitive processing domains, such as perceptual decision-making. Extending this body of evidence, we investigated MC monitoring by asking children to solve arithmetic problems, an educationally relevant higher-order process, while providing concurrent MC reports during fMRI acquisition. Results are reported on 50 primary school children …
The Temporal Dynamics Of Ensemble Perception, Michael L. Epstein
The Temporal Dynamics Of Ensemble Perception, Michael L. Epstein
Dissertations, Theses, and Capstone Projects
The striking disparity between the subjective richness of experience and the considerable limitations of perceptual processing has emerged as an essential, enduring question in both vision science and philosophy of mind. A potential solution to this issue is ensemble perception: the ability for the visual system to compute the statistical summaries of object groups, effectively compressing an otherwise overwhelming amount of information. Previous work has supported that ensemble statistics can be perceived quickly and accurately for a wide range of object features. This has motivated models of ensemble perception as an early process in vision, providing an initial sense of …
Neurodevelopmental Mechanisms Of Adverse Trauma Outcomes In Emerging Adulthood, Olena Kleshchova
Neurodevelopmental Mechanisms Of Adverse Trauma Outcomes In Emerging Adulthood, Olena Kleshchova
Dissertations, Theses, and Capstone Projects
Background: Exposure to traumatic stress and adversity during the formative years of development can have adverse effects on mental health, neuroendocrine stress system function, and the brain, that persist into adulthood. One candidate mechanism that might confer vulnerability to enduring adverse outcomes of early life trauma is disruption of normal brain maturation. As the brain matures, functional interactions among brain regions change until the functional brain architecture (i.e., the functional connectome) reaches a mature state in adulthood. Given that different neural circuits have distinct developmental trajectories and sensitive periods, traumatic stress at a given point in development might have …
Homotopic Coupling In Persons With Epilepsy Using Movie-Driven And Resting-State Fmri, Caroline M. Chadwick
Homotopic Coupling In Persons With Epilepsy Using Movie-Driven And Resting-State Fmri, Caroline M. Chadwick
Electronic Thesis and Dissertation Repository
For the 30-40% of persons with epilepsy (PWE) with refractory epilepsy, seizure freedom following surgery is affected by the localization of the epileptogenic zone (EZ). However, functional abnormalities can exist at a distance from the EZ, which may contribute to variable outcomes after surgery. Considering epilepsy as a network disorder (Pittau & Vulliemoz, 2015), and evaluating functional coupling among homotopic brain areas, may help predict cognitive outcomes. Homotopic areas are well connected anatomically and undoubtedly work synchronously to generate cognition. We evaluated 22 persons with focal epilepsy and 24 neurologically healthy controls using fMRI at rest and while watching a …
Response To Uncertain Threat In Acute Trauma Survivors, Kenneth Bennett
Response To Uncertain Threat In Acute Trauma Survivors, Kenneth Bennett
Theses and Dissertations
Uncertainty is often associated with subjective distress and a potentiated anxiety response. The heightened response to uncertainty may be a central mechanism via which anxiety-, trauma-, and stressor-related disorders are developed and maintained. The current study compared the neural response to predictable and unpredictable threat in acute trauma survivors to clarify the role of the response to uncertain threat in fear circuitry and further inform the nature of the development of PTSD in the context of uncertain threat. The novel study showed that anticipating unpredictable (primarily negative images) relative to predictable images increased activation in a frontoparietal network and was …
Neural Mechanisms Of Cognitive Individual Difference: An Investigation Of The Human Connectome Project, Shelly Renee Cooper
Neural Mechanisms Of Cognitive Individual Difference: An Investigation Of The Human Connectome Project, Shelly Renee Cooper
Arts & Sciences Electronic Theses and Dissertations
Considering individual differences in task activation functional magnetic resonance imaging (t-fMRI) can be challenging because they may arise from variability in activity in brain regions, in the tasks themselves, or some combination thereof. Delineating sources of between-subjects variance is particularly important for cognitive control where task goals are at the forefront. Here we applied structural equation modeling (SEM) to the Human Connectome Project to examine if activity could be partitioned into separable brain and task individual difference dimensions. A series of SEMs were defined with varying numbers of latent factors, where the inputs were parcels of two cognitive control-related brain …
Neural Substrates Of Active Avoidance And Its Impact On Fear Extinction, Elizabeth Parisi
Neural Substrates Of Active Avoidance And Its Impact On Fear Extinction, Elizabeth Parisi
Theses and Dissertations
Models of anxiety suggest that avoidance of a conditioned fear stimulus prevents new safety learning, thereby serving to maintain fear. However, there is little empirical data in humans on the impact of avoidance of conditioned fear stimuli on subsequent fear extinction. In the present study I investigated the effect of avoidance of threat on neural activity during avoidance/control and a subsequent extinction phase using ultra high-resolution (7T) fMRI. Results indicated that active avoidance was associated with increased activity in regions involved in reward prediction, but this did not differentiate active avoidance from an active control condition. Neural activation during the …
Malleability Of Neural Activity In Response To Treatment: Fmri Biomarkers Across Intervention For Autistic Adolescents, Alana J. Mcvey
Malleability Of Neural Activity In Response To Treatment: Fmri Biomarkers Across Intervention For Autistic Adolescents, Alana J. Mcvey
Dissertations (1934 -)
Autistic adolescents frequently experience clinical levels of anxiety which exacerbate social difficulties. Those that receive a well-validated social skills intervention, the Program for the Education and Enrichment of Relational Skills (PEERS®), have shown improvements in both social behavior and anxiety. Prior literature has demonstrated neural changes in response to this intervention using EEG, and recent literature highlights the importance of using neural markers to assess for intervention response in autism. No study to date, however, has examined changes in neural activity via fMRI and links with social behavior and anxiety across the PEERS® intervention for autistic adolescents. Thus, the present …