Psychology Commons^™

Functional Neuroimaging In A Pediatric Case Of Impaired Awareness, Christopher Richard N Nicholas

Doctoral Dissertations

Disorders of consciousness (DOC) occur in severe cases of neurological disease and acquired brain injury, spanning the continuum from complete unresponsiveness (vegetative state) to partial conscious awareness with only erratic voluntary behavioral responses (minimally conscious state). Assessing the patient’s level of awareness of self and their environment through behavioral evaluation is notoriously difficult and may lead to misdiagnosis if residual cognitive function goes undetected. A number of studies (Di et al., 2007; Staffen et al., 2008; Coleman et al., 2007; Qin et al., 2010) applying brain-imaging methods to measure brain activity associated with processing self-referential stimuli (stimuli related to the …