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Full-Text Articles in Psychology

Catecholaminergic Neuromodulation Shapes Intrinsic Mri Functional Connectivity In The Human Brain, Ruud L. Van Den Brink, Thomas Pfeffer, Christopher M. Warren, Peter R. Murphy, Klodiana-Daphne Tona, Nic J. Van Der Wee, Eric Giltay, Martijn S. Van Noorden, Serge A. Rombouts, Tobias H. Donner, Sander Nieuwenhuis Jul 2016

Catecholaminergic Neuromodulation Shapes Intrinsic Mri Functional Connectivity In The Human Brain, Ruud L. Van Den Brink, Thomas Pfeffer, Christopher M. Warren, Peter R. Murphy, Klodiana-Daphne Tona, Nic J. Van Der Wee, Eric Giltay, Martijn S. Van Noorden, Serge A. Rombouts, Tobias H. Donner, Sander Nieuwenhuis

Psychology Faculty Publications

The brain commonly exhibits spontaneous (i.e., in the absence of a task) fluctuations in neural activity that are correlated across brain regions. It has been established that the spatial structure, or topography, of these intrinsic correlations is in part determined by the fixed anatomical connectivity between regions. However, it remains unclear which factors dynamically sculpt this topography as a function of brain state. Potential candidate factors are subcortical catecholaminergic neuromodulatory systems, such as the locus ceruleus-norepinephrine system, which send diffuse projections to most parts of the forebrain. Here, we systematically characterized the effects of endogenous central neuromodulation on correlated fluctuations …


Catecholamine-Mediated Increases In Neural Gain Improve The Precision Of Cortical Representations, Christopher M. Warren, Eran Eldar, Ruud L. Van Den Brink, Klodiana-Daphne Tona, Nic J. Van Der Wee, Eric J. Giltay, Martijn S. Van Noorden, Jos A. Bosch, Robert C. Wilson, Jonathan D. Cohen, Sander Nieuwenhuis May 2016

Catecholamine-Mediated Increases In Neural Gain Improve The Precision Of Cortical Representations, Christopher M. Warren, Eran Eldar, Ruud L. Van Den Brink, Klodiana-Daphne Tona, Nic J. Van Der Wee, Eric J. Giltay, Martijn S. Van Noorden, Jos A. Bosch, Robert C. Wilson, Jonathan D. Cohen, Sander Nieuwenhuis

Psychology Faculty Publications

Neurophysiological evidence suggests that neuromodulators, such as norepinephrine and dopamine, increase neural gain in target brain areas. Computational models and prominent theoretical frameworks indicate that this should enhance the precision of neural representations, but direct empirical evidence for this hypothesis is lacking. In two functional MRI studies, we examine the effect of baseline catecholamine levels (as indexed by pupil diameter and manipulated pharmacologically) on the precision of object representations in the human ventral temporal cortex using angular dispersion, a powerful, multivariate metric of representational similarity (precision). We first report the results of computational model simulations indicating that increasing catecholaminergic gain …


Perspectives On The Use Of Acceptance And Commitment Therapy Related Mobile Apps: Results From A Survey Of Students And Professionals, Benjamin G. Pierce, Michael P. Twohig, Michael E. Levin Jan 2016

Perspectives On The Use Of Acceptance And Commitment Therapy Related Mobile Apps: Results From A Survey Of Students And Professionals, Benjamin G. Pierce, Michael P. Twohig, Michael E. Levin

Psychology Faculty Publications

Although mobile apps have proliferated as self-help or adjunctive therapy supports, scant research has explored their implementation among mental health practitioners. Little is known about uses and perceptions of mental health apps among applied practitioners, nor are agreed-upon criteria for evaluating and choosing apps available. The present survey study examined the uses and perceptions of mental health apps among 356 professionals and students familiar with Acceptance and Commitment Therapy (ACT), as indicated by being a member of the Association for Contextual Behavioral Science. The survey found that practitioners are interested in using ACT-related apps, but that use of and familiarity …