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Aberrant Functioning Of The Theory-Of-Mind Network In Children And Adolescents With Autism., Rajesh Kana, Jose Maximo, Diane Williams, Timothy Keller, Sarah Schipul, Vladimir Cherkassky, Nancy Minshew, Marcel Just
Aberrant Functioning Of The Theory-Of-Mind Network In Children And Adolescents With Autism., Rajesh Kana, Jose Maximo, Diane Williams, Timothy Keller, Sarah Schipul, Vladimir Cherkassky, Nancy Minshew, Marcel Just
Marcel Adam Just
Background: Theory-of-Mind (ToM), the ability to infer people’s thoughts and feelings, is a pivotal skill in effective social interactions. Individuals with autism spectrum disorders (ASD) have been found to have altered ToM skills, which significantly impacts the quality of their social interactions. Neuroimaging studies have reported altered activation of the ToM cortical network, especially in adults with autism, yet little is known about the brain responses underlying ToM in younger individuals with ASD. This functional magnetic resonance imaging (fMRI) study investigated the neural mechanisms underlying ToM in high-functioning children and adolescents with ASD and matched typically developing (TD) peers.
Methods: …