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Fractionating Choice: A Study On Reward Discrimination, Preference, And Relative Valuation In The Rat (Rattus Norvegicus), Joshua M. Ricker, Justin D. Hatch, Daniel D. Powers, Howard C. Cromwell
Fractionating Choice: A Study On Reward Discrimination, Preference, And Relative Valuation In The Rat (Rattus Norvegicus), Joshua M. Ricker, Justin D. Hatch, Daniel D. Powers, Howard C. Cromwell
Howard Casey Cromwell
Choice behavior combines discrimination between distinctive outcomes, preference for specific outcomes and relative valuation of comparable outcomes. Previous work has focused on 1 component (i.e., preference) disregarding other influential processes that might provide a more complete understanding. Animal models of choice have been explored primarily utilizing extensive training, limited freedom for multiple decisions and sparse behavioral measures constrained to a single phase of motivated action. The present study used a paradigm that combines different elements of previous methods with the goal to distinguish among components of choice and explore how well components match predictions based on risk-sensitive foraging strategies. In …
Reportinfluence Of Emotional States On Inhibitory Gating: Animal Models To Clinical Neurophysiology, Howard Cromwell
Reportinfluence Of Emotional States On Inhibitory Gating: Animal Models To Clinical Neurophysiology, Howard Cromwell
Howard Casey Cromwell
tIntegrating research efforts using a cross-domain approach could redefine traditional constructs used inbehavioral and clinical neuroscience by demonstrating that behavior and mental processes arise not fromfunctional isolation but from integration. Our research group has been examining the interface betweencognitive and emotional processes by studying inhibitory gating. Inhibitory gating can be measured viachanges in behavior or neural signal processing. Sensorimotor gating of the startle response is a well-usedmeasure. To study how emotion and cognition interact during startle modulation in the animal model,we examined ultrasonic vocalization (USV) emissions during acoustic startle and prepulse inhibition. Wefound high rates of USV emission during the …