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Full-Text Articles in Psychology
Assessment Of Peripheral Bdnf Levels Over 30 Days, Sally Hang
Assessment Of Peripheral Bdnf Levels Over 30 Days, Sally Hang
Cal Poly Humboldt theses and projects
Brain health, and the benefits of exercise have been linked to the biological signaling molecule called brain-derived neurotrophic factor (BDNF). Animal and human studies have provided some support for physical exercise as a mechanism for increasing BDNF levels. However, results have been inconsistent, which may be attributed in part to incomplete information about normal variation in circulating peripheral BDNF levels. This investigation examined capillary-drawn whole blood samples from nine healthy adult participants over 30 days with the goal of documenting variability in resting BDNF levels and changes that may be attributed to physical exercise. It was hypothesized that BDNF concentrations …
Investigating Differing Degrees Of Foxo3a Expression In Adult Neural Stem Cells Between Age Groups In Zebrafish, Francis G. Bacik
Investigating Differing Degrees Of Foxo3a Expression In Adult Neural Stem Cells Between Age Groups In Zebrafish, Francis G. Bacik
Cal Poly Humboldt theses and projects
One factor influencing organismal longevity is the activity of transcription factors of the “fork head domain” family, otherwise known as “Forkhead box” (Fox) proteins. Studies of the four isoforms of the “O” subclass of Fox proteins found in human genes have revealed a direct relationship between FoxO3a-dependent gene expression and the conservation of neural stem cell (NSC) in the adult brain, specifically in the subgranular zone of the dentate gyrus in the hippocampus and the subventricular zone of the cortex. This transcription factor has also been shown to regulate apoptosis in nervous tissue during embryonic development in zebrafish. The current …