Psychology Commons^™

Extraocular Muscle Activity, Rapid Eye Movements And The Development Of Active And Quiet Sleep, Adele M. H. Seelke, Andrew J. Gall, Karl Æ. Karlsson, Mark S. Blumberg

Faculty Publications

Rapid eye movements (REMs), traditionally measured using the electrooculogram (EOG), help to characterize active sleep in adults. In early infancy, however, they are not clearly expressed. Here we measured extraocular muscle activity in infant rats at 3 days of age (P3), P8 and P14-15 in order to assess the ontogeny of REMs and their relationship with other forms of sleep-related phasic activity. We found that the causal relationship between extraocular muscle twitches and REMs strengthened during the first two postnatal weeks, reflecting increased control of the extraocular muscles over eye movements. As early as P3, however, phasic bursts of extraocular …

The Neural Substrates Of Infant Sleep In Rats, Karl Æ. Karlsson, Andrew J. Gall, Ethan J. Mohns, Adele M. H. Seelke, Mark S. Blumberg

Faculty Publications

Sleep is a poorly understood behavior that predominates during infancy but is studied almost exclusively in adults. One perceived impediment to investigations of sleep early in ontogeny is the absence of state-dependent neocortical activity. Nonetheless, in infant rats, sleep is reliably characterized by the presence of tonic (i.e., muscle atonia) and phasic (i.e., myoclonic twitching) components; the neural circuitry underlying these components, however, is unknown. Recently, we described a medullary inhibitory area (MIA) in week-old rats that is necessary but not sufficient for the normal expression of atonia. Here we report that the infant MIA receives projections from areas containing …

Daily Rhythm Of Cerebral Blood Flow Velocity, Deirdre A. Conroy, Arthur J. Spielman, Rebecca Q. Scott

Publications and Research

Background: CBFV (cerebral blood flow velocity) is lower in the morning than in the afternoon and evening. Two hypotheses have been proposed to explain the time of day changes in CBFV: 1) CBFV changes are due to sleep-associated processes or 2) time of day changes in CBFV are due to an endogenous circadian rhythm independent of sleep. The aim of this study was to examine CBFV over 30 hours of sustained wakefulness to determine whether CBFV exhibits fluctuations associated with time of day.

Methods: Eleven subjects underwent a modified constant routine protocol. CBFV from the middle cerebral artery was monitored …

Brain Mappings Of The Arithmetic Processing In Children And Adults., Fábio T. Rocha, Armando F. Rocha, Eduardo Massad, Renee Menezes

Armando F Rocha

Despite the increasing number of experimental mapping showing that human arithmetic cognition is supported by widely spread neural circuits; the theoretical reasoning about these data remains mostly metaphorical and guided by a connectionist approach. Although neurons at distinct areas in the brain are assumed to take charge of different duties in the solution of the experimental task, the results are always discussed by hypothesizing some association between the different areas without questioning any difference of behavior at the level of the neurons at each of these areas. Here, the brain is assumed as Distributed Intelligent Processing System (DIPS) formed by …

The Temporal Context Model In Spatial Navigation And Relational Learning: Toward A Common Explanation Of Medial Temporal Lobe Function Across Domains, Marc W. Howard, Mrigankka S. Fotedar, Aditya V. Datey, Michael E. Hasselmo

Psychology - All Scholarship

The medial temporal lobe (MTL) has been studied extensively at all levels of analysis, yet its function remains unclear. Theory regarding the cognitive function of the MTL has centered along 3 themes. Different authors have emphasized the role of the MTL in episodic recall, spatial navigation, or relational memory. Starting with the temporal context model (M.W. Howard and M. J. Kahana, 2002), a distributed memory model that has been applied to benchmark data from episodic recall tasks, the authors propose that the entorhinal cortex supports a gradually changing representation of temporal context and the hippocampus proper enables retrieval of these …

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell

Laura Elena O'Dell

No abstract provided.

Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell

Laura Elena O'Dell

No abstract provided.

Interaction Between The Dorsal And Ventral Pathways In Mental Rotation: An Fmri Study, Hideya Koshino, Patricia Carpenter, Timothy Keller, Marcel Just

Marcel Adam Just

No abstract provided.

Imagining Material Versus Geometric Properties Of Objects: An Fmri Study, Sharlene Newman, Roberta Klatzky, Susan Lederman, Marcel Just

Marcel Adam Just

No abstract provided.

Functional Connectivity In An Fmri Working Memory Task In High-Functioning Autism, Hideya Koshino, Patricia Carpenter, Nancy Minshew, Vladimir Cherkassky, Timothy Keller, Marcel Just

Marcel Adam Just

No abstract provided.

The Framing Effect And Risky Decisions: Examining Cognitive Functions With Fmri, Cleotilde Gonzalez, Jason Dana, Hideya Koshino, Marcel Adam Just

Marcel Adam Just

No abstract provided.