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Mdma And Learning: Effects Of Acute And Neurotoxic Exposure, Thomas P. Byrne
Mdma And Learning: Effects Of Acute And Neurotoxic Exposure, Thomas P. Byrne
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In two experiments, the effects of MDMA were examined on the acquisition of lever-press responding by rats exposed to procedures in which water delivery was delayed by 0, 10, or 20 seconds. In the first experiment, naive, water-deprived rats received an intraperitoneal injection of MDMA (0, 1.0, 3.2, or 5.6 mg/kg) prior to one experimental session. Response acquisition was observed under all conditions at all drug doses. MDMA increased both response rates and reinforcers earned in a dose-dependent fashion, but only when reinforcement was immediate. Under conditions of delay, MDMA had no effect on the number of lever presses emitted …