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Neural Correlates Of Memories Of Abandonment In Women With And Without Borderline Personality Disorder, Christian G. Schmahl, Bernet M. Elzinga, Eric Vermetten, Charles A. Sanislow, Thomas H. Mcglashan, J. Douglas Bremner
Neural Correlates Of Memories Of Abandonment In Women With And Without Borderline Personality Disorder, Christian G. Schmahl, Bernet M. Elzinga, Eric Vermetten, Charles A. Sanislow, Thomas H. Mcglashan, J. Douglas Bremner
Charles A. Sanislow, Ph.D.
BACKGROUND: Borderline personality disorder (BPD) is a common psychiatric disorder that is often linked to early stressors. One particularly salient feature of the disorder is fear of abandonment. This pilot study was conducted to measure neural correlates of memories of abandonment in women with and without BPD.
METHODS: Twenty women with a history of childhood sexual abuse underwent measurement of brain blood flow with positron emission tomography imaging while they listened to scripts describing neutral and personal abandonment events. Brain blood flow during exposure to abandonment and neutral scripts was compared among women with and without BPD.
RESULTS: Memories of …