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An Exploratory Study Of Varying Phenotypes Of Posttraumatic Stress Among A Comorbid Substance Misuse Population, Dennis Allen Donahue Dec 2020

An Exploratory Study Of Varying Phenotypes Of Posttraumatic Stress Among A Comorbid Substance Misuse Population, Dennis Allen Donahue

Doctoral Dissertations

Objective: The purpose of this study was to explore differences in presentation of posttraumatic distress (PTD) that may represent different phenotypes, such as a possible cognitively-driven variant, in addition to those rooted in the prevailing conditioned-fear model. In conjunction, links to substance misuse and a purposeful selection bias for specific drugs-of-choice (DoC) based on phenotype variation were examined. Method: A convenience sample of inpatients in residential treatment for substance misuse who also endorsed posttraumatic distress following at least one previous traumatic experience (N = 177) completed self-report assessments and an in-person direct inquiry. Results: Hierarchical cluster analysis and ANOVA …