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Full-Text Articles in Psychology

Relation Of Depression Symptoms To Sustained Reward And Loss Sensitivity, Michael P. Berry, Ema Tanovic, Jutta Joormann, Charles A. Sanislow Feb 2019

Relation Of Depression Symptoms To Sustained Reward And Loss Sensitivity, Michael P. Berry, Ema Tanovic, Jutta Joormann, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

Depression is characterized by altered sensitivity to rewards, with recent evidence suggesting that the ability to sustain responses to rewards across long experimental tasks is diminished. Most work on sustained reward responsiveness has taken a cat- egorical approach and focused on major depressive disorder. However, impairments in reward sensitivity are also found at lower levels of symptom severity and may be relevant for understanding basic mechanisms linking reward processing abnormali- ties to depression. The current study took a dimensional approach to examine the relation between depression symptoms and sustained reward responsiveness by examining how early neural responses to rewards and …


Nimh Research Domain Criteria (Rdoc), Charles A. Sanislow, Kevin J. Quinn, Isaiah Sypher Dec 2014

Nimh Research Domain Criteria (Rdoc), Charles A. Sanislow, Kevin J. Quinn, Isaiah Sypher

Charles A. Sanislow, Ph.D.

The Research Domain Criteria (RDoC) project is a framework for studying domains of biological and behavioral function that cut across traditional psychiatric diagnostic boundaries with the long-term objective of creating a new nosology based on specific biobehavioral measures. The initial aim is to provide a framework to drive clinical research. One goal of RDoC is to facilitate the development of biomarkers that could eventually be used for practical clinical diagnostic purposes and allow the development of new treatments targeting specific mechanisms of mental illness. In this entry, RDoC, its development, and the ways that it may evolve are described.