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Neuroscience and Neurobiology

Graduate College Dissertations and Theses

2015

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The Influence Of Prenatal Stress On Behaviors Associated With Schizophrenia And Autism Spectrum Disorder., Harold Bauerle Jan 2015

The Influence Of Prenatal Stress On Behaviors Associated With Schizophrenia And Autism Spectrum Disorder., Harold Bauerle

Graduate College Dissertations and Theses

Disorders such as schizophrenia (SCZ) and austism spectrum disorder (ASD) have long been associated with prenatal stress. In these three experiments, we attempted to correlate stress during gestation with behaviors considered to have good facial validity with SCZ and ASD in both juvenile and adult animals. To differentiate the effects of prenatal stress (PS) from the effects of early life stress due to a dam's behavior (MS), half of offspring animals were cross fostered to dams treated in the alternative condition as the offspring during pregnancy in experiments 2 and 3. In experiment 1, but not in 2 or 3, …