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Psychology Commons

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Neuroscience and Neurobiology

Hope College

19th Annual Celebration of Undergraduate Research and Creative Activity (2020)

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Full-Text Articles in Psychology

The Influence Of Hsv-1 Infection On Circadian Rhythms And Behavior In Mice, Lauren Evert, Kevin Catalfano, Victoria Gardner, Anna Lunderberg Apr 2020

The Influence Of Hsv-1 Infection On Circadian Rhythms And Behavior In Mice, Lauren Evert, Kevin Catalfano, Victoria Gardner, Anna Lunderberg

19th Annual Celebration of Undergraduate Research and Creative Activity (2020)

Herpes simplex virus 1 (HSV-1) infection is a lifelong viral infection that affects approximately half of the human population (McQuillan et al., 2018), yet little is known about its neurological effects. There is correlational evidence that infection with HSV-1 can induce cognitive decline and increased anxiety behaviors (Harris & Harris, 2015; Steel & Eslick, 2015; Tarter, Simanek, Dowd, & Aiello, 2014). In addition, HSV-1 may be associated with disruptions to circadian rhythms because HSV-1 is associated with chronic fatigue syndrome (Bond & Dinan, 2006), the time of HSV-1 infection impacts the viral replication (Edgar, 2016), and HSV impacts CLOCK machinery …