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Neuroscience and Neurobiology

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Full-Text Articles in Psychology

Neural Underpinnings Of Working Memory In Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Sabrina Na, Hui Mao Jan 2015

Neural Underpinnings Of Working Memory In Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Sabrina Na, Hui Mao

Psychology Faculty Publications

Objective: Adult survivors of childhood brain tumors are at risk for cognitive performance deficits that require the core cognitive skill of working memory. Our goal was to examine the neural mechanisms underlying working memory performance in survivors. Method: We studied the working memory of adult survivors of pediatric posterior fossa brain tumors using a letter n-back paradigm with varying cognitive workload (0-, 1-, 2-, and 3-back) and functional magnetic resonance imaging as well as neuropsychological measures. Results: Survivors of childhood brain tumors evidenced lower working memory performance than demographically-matched healthy controls. Whole-brain analyses revealed significantly greater blood-oxygen level dependent (BOLD) …


The Impact Of Sleep Quality On Cognitive Functioning In Parkinson's Disease, Karina Stavitsky, Sandra Neargarder, Yelena Bogdanova, Patrick Mcnamara, Alice Cronin-Golomb Jan 2012

The Impact Of Sleep Quality On Cognitive Functioning In Parkinson's Disease, Karina Stavitsky, Sandra Neargarder, Yelena Bogdanova, Patrick Mcnamara, Alice Cronin-Golomb

Psychology Faculty Publications

In healthy individuals and those with insomnia, poor sleep quality is associated with decrements in performance on tests of cognition, especially executive function. Sleep disturbances and cognitive deficits are both prevalent in Parkinson's disease (PD). Sleep problems occur in over 75% of patients, with sleep fragmentation and decreased sleep efficiency being the most common sleep complaints, but their relation to cognition is unknown. We examined the association between sleep quality and cognition in PD. In 35 non-demented individuals with PD and 18 normal control adults (NC), sleep was measured using 24-hr wrist actigraphy over 7 days. Cognitive domains tested included …