Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Psychology
Stereological Assessment Of The Thalamus In A Rat Model Of Periventricular Nodular Heterotopia, Jason Lennox
Stereological Assessment Of The Thalamus In A Rat Model Of Periventricular Nodular Heterotopia, Jason Lennox
Honors Projects
Malformations of neocortical development such as microgyria (MG) and periventricular nodular heterotopia (PNH) have been observed in the brains of language learning impaired (LLI) humans. Rats with MG have shown rapid auditory processing (RAP) deficits similar to acoustic deficits observed in some human LLI populations. Threlkeld et al., (2009) previously reported RAP and other learning impairments in rats with PNH resulting from disruption to embryonic neuronal cell division by way of Methylazoxymethanol (MAM) treatment on embryonic day 15 (E15). The thalamus and its subnuclei may be vulnerable to neurodevelopmental disruptions. Studies of MG rats have shown changes in cell size …