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Hippocampal Volume And Auditory Attention On A Verbal Memory Task With Adult Survivors Of Pediatric Brain Tumor, Reema Jayakar, Tricia Z. King, Robin Morris, Sabrina Na
Hippocampal Volume And Auditory Attention On A Verbal Memory Task With Adult Survivors Of Pediatric Brain Tumor, Reema Jayakar, Tricia Z. King, Robin Morris, Sabrina Na
Psychology Faculty Publications
Objective: We examined the nature of verbal memory deficits and the possible hippocampal underpinnings in long-term adult survivors of childhood brain tumor. Method: 35 survivors (M=24.10±4.93 years at testing; 54% female), on average 15 years post-diagnosis, and 59 typically developing adults (M=22.40±4.35 years, 54% female) participated. Automated FMRIB Software Library (FSL) tools were used to measure hippocampal, putamen, and whole brain volumes. The California Verbal Learning Test – Second Edition (CVLT-II) was used to assess verbal memory. Results: Hippocampal (F(1,91)=4.06, ηp2=.04), putamen (F(1,91)=11.18, ηp2=.11), and whole brain (F(1,92)=18.51, …
Adolescent Bisphenol-A Exposure Decreases Dendritic Spine Density: Role Of Sex And Age, Rachel E. Bowman, Victoria N. Luine, Hameda Khandaker, Joseph J. Villafane, Maya Frankfurt
Adolescent Bisphenol-A Exposure Decreases Dendritic Spine Density: Role Of Sex And Age, Rachel E. Bowman, Victoria N. Luine, Hameda Khandaker, Joseph J. Villafane, Maya Frankfurt
Psychology Faculty Publications
Bisphenol-A (BPA), a common environmental endocrine disruptor, modulates estrogenic, androgenic, and anti-androgenic effects throughout the lifespan. We recently showed that low dose BPA exposure during adolescence increases anxiety and impairs spatial memory independent of sex. In the current study, six week old Sprague Dawley rats (n=24 males, n=24 females) received daily subcutaneous injections (40 µg/kg bodyweight) of BPA or vehicle for one week. Serum corticosterone levels in response to a 1 h restraint stress and spine density were examined at age 7 (cohort 1) and 11 (cohort 2) weeks. Adolescent BPA exposure did not alter stress dependent corticosterone responses but …