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Full-Text Articles in Psychology
The Development Of Day-Night Differences In Sleep And Wakefulness In Norway Rats And The Effect Of Bilateral Enucleation, Andrew J. Gall, William D. Todd, Baisali Ray, Cassandra M. Coleman, Mark S. Blumberg
The Development Of Day-Night Differences In Sleep And Wakefulness In Norway Rats And The Effect Of Bilateral Enucleation, Andrew J. Gall, William D. Todd, Baisali Ray, Cassandra M. Coleman, Mark S. Blumberg
Faculty Publications
The suprachiasmatic nucleus (SCN) exhibits circadian rhythmicity in fetal and infant rats, but little is known about the consequences of this rhythmicity for infant behavior. Here, in Experiment 1, we measured sleep and wakefulness in rats during the day and night in postnatal day (P)2, P8, P15 and P21 subjects. As early as P2, day-night differences in sleep-wake activity were detected. Nocturnal wakefulness began to emerge around P15 and was reliably expressed by P21. We hypothesized that the process of photic entrainment over the first postnatal week, which depends upon the development of connectivity between the retinohypothalamic tract (RHT) and …
Brainstem Cholinergic Modulation Of Muscle Tone In Infant Rats, Andrew J. Gall, Amy Poremba, Mark S. Blumberg
Brainstem Cholinergic Modulation Of Muscle Tone In Infant Rats, Andrew J. Gall, Amy Poremba, Mark S. Blumberg
Faculty Publications
In week-old rats, lesions of the dorsolateral pontine tegmentum (DLPT) and nucleus pontis oralis (PnO) have opposing effects on nuchal muscle tone. Specifically, pups with DLPT lesions exhibit prolonged bouts of nuchal muscle atonia (indicative of sleep) and pups with PnO lesions exhibit prolonged bouts of high nuchal muscle tone (indicative of wakefulness). Here we test the hypothesis that nuchal muscle tone is modulated, at least in part, by cholinergically mediated interactions between these two regions. First, in unanesthetized pups, we found that chemical infusion of the cholinergic agonist carbachol (22 mM, 0.1 µL) within the DLPT produced high muscle …