Psychology Commons^™

Day-Night Differences In Neural Activation In Histaminergic And Serotonergic Areas With Putative Projections To The Cerebrospinal Fluid In A Diurnal Brain, Alexandra Castillo-Ruiz, Andrew J. Gall, Laura Smale, Antonio A. Nunez

Faculty Publications

In nocturnal rodents, brain areas that promote wakefulness have a circadian pattern of neural activation that mirrors the sleep/wake cycle, with more neural activation during the active phase than during the rest phase. To investigate whether differences in temporal patterns of neural activity in wake-promoting regions contribute to differences in daily patterns of wakefulness between nocturnal and diurnal species, we assessed Fos expression patterns in the tuberomammillary (TMM), supramammillary (SUM), and raphe nuclei of male grass rats maintained in a 12:12 h light-dark cycle. Day-night profiles of Fos expression were observed in the ventral and dorsal TMM, in the SUM, …