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Full-Text Articles in Psychology

The Effects Of Nicotine In The Neonatal Quinpirole Rodent Model Of Psychosis: Neural Plasticity Mechanisms And Nicotinic Receptor Changes, Daniel J. Peterson, W. Drew Gill, John M. Dose, Donald B. Hoover, James R. Pauly, Elizabeth D. Cummins, Katherine C. Burgess, Russell W. Brown May 2017

The Effects Of Nicotine In The Neonatal Quinpirole Rodent Model Of Psychosis: Neural Plasticity Mechanisms And Nicotinic Receptor Changes, Daniel J. Peterson, W. Drew Gill, John M. Dose, Donald B. Hoover, James R. Pauly, Elizabeth D. Cummins, Katherine C. Burgess, Russell W. Brown

Pharmaceutical Sciences Faculty Publications

Neonatal quinpirole (NQ) treatment to rats increases dopamine D2 receptor sensitivity persistent throughout the animal’s lifetime. In Experiment 1, we analyzed the role of α7 and α4β2 nicotinic receptors (nAChRs) in nicotine behavioral sensitization and on the brain-derived neurotrophic factor (BDNF) response to nicotine in NQ- and neonatally saline (NS)-treated rats. In Experiment 2, we analyzed changes in α7 and α4β2 nAChR density in the nucleus accumbens (NAcc) and dorsal striatum in NQ and NS animals sensitized to nicotine. Male and female Sprague-Dawley rats were neonatally treated with quinpirole (1 mg/kg) or saline from postnatal days (P)1–21. Animals were given …


The Effects Of Community Type And Sexual Orientation On Adolescent Alcohol Abuse: A Retrospective Exploration, Karla Beth Moore Jan 2017

The Effects Of Community Type And Sexual Orientation On Adolescent Alcohol Abuse: A Retrospective Exploration, Karla Beth Moore

Theses, Dissertations and Capstones

Considerable research has demonstrated that adolescents, as a whole, are experimenting with alcohol at alarming rates (Biddle, Bank, & Marlin, 1980; Donath, et al., 2011;King, Chassin, & Molina, 2009). However, research is very mixed on findings identifying which groups of adolescents tend to be most at risk for using alcohol, as well as the reasons these groups identify for such experimentation (Carlo, Crockett, Wilkinson, & Beal, 2011; Coomber, Toumbourou, Miller, Staiger, Hemphill, & Catalano, 2011). The current study examined participants from various community types and sexual orientations, in a retrospective manner. Participants (ages 18 and over) answered questions on a …