Psychology Commons^™

Evaluation Of The Discriminable Stimulus Effects Of 0.3 Mg/Kg 3, 4‑Methylenedioxypyrovalerone (Mdpv) And 1.0 Mg/Kg 4-Methylmethcathinone (4-Mmc) Using A Drug Discrimination Procedure In Male Sprague-Dawley Rats, Michael Berquist

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Experimental investigations into the behavioral and neurochemical effects of illicit β-ketophenethylamines (synthetic cathinones, “bath salts”) has increased in recent years. Two cathinone derivatives in particular, MDPV and mephedrone (4-MMC), have received a considerable amount of research attention given their relative popularity among users at the turn of the 21st century. Researchers investigating MDPV and 4-MMC have devoted much of their attention toward evaluating the drugs’ reinforcing efficacy, rewarding effects, receptor binding profiles, and effects on ambulatory responses.

There exist few published studies that have evaluated the discriminable stimulus effects of MDPV and 4-MMC using rodent drug discrimination procedures. To date, …