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Subtle Cognitive Impairment In Elders With Mini-Mental State Examination Scores Within The ‘Normal’ Range, Tim Friedman, G Yelland, S Robinson
Subtle Cognitive Impairment In Elders With Mini-Mental State Examination Scores Within The ‘Normal’ Range, Tim Friedman, G Yelland, S Robinson
Dr Tim Friedman
The Mini-Mental State Examination (MMSE) is commonly used as a screening test for dementia, yet MMSE scores above the cut-off for dementia (24–30) are widely thought to have limited utility, particularly in older persons. The study investigates whether scores within this range can be indicative of pre-symptomatic levels of cognitive impairment. Ninety-six community-dwelling older persons aged 62–89 years (mean = 75.2 years), who had obtained MMSE scores between 25 and 30, were tested on the computer-based Subtle Cognitive Impairment Test (SCIT). Compared with individuals who obtained a perfect score of 30 on the MMSE, individuals with scores of 28–29 made …
Impaired Perceptual Judgement At Low Blood Alcohol Concentrations, Tim Friedman, S Robinson, G Yelland
Impaired Perceptual Judgement At Low Blood Alcohol Concentrations, Tim Friedman, S Robinson, G Yelland
Dr Tim Friedman
Males and females show different patterns of cognitive impairment when blood alcohol concentrations (BACs) are high. To investigate whether gender differences persist at low BACs, cognitive impairment was tested in 21 participants (11 female, 10 male) using a brief computerized perceptual judgment task that provides error rate and response time data. Participants consumed a measured dose of alcohol (average peak BAC: females: 0.052 g/100 mL, males: 0.055 g/100 mL), and were tested at four time points spanning both the rising and falling limbs of the BAC curve, in addition to a prealcohol time point. Comparisons were made against performance of …