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Differential Effects Of Alzheimer's Disease And Huntington's Disease On The Performance Of Mental Rotation, Tara T. Lineweaver, David P. Salmon, Mark W. Bondi, Jody Corey-Bloom
Differential Effects Of Alzheimer's Disease And Huntington's Disease On The Performance Of Mental Rotation, Tara T. Lineweaver, David P. Salmon, Mark W. Bondi, Jody Corey-Bloom
Scholarship and Professional Work - LAS
he ability to spatially rotate a mental image was compared in patients with Alzheimer's disease (AD; n = 18) and patients with Huntington's disease (HD; n = 18). Compared to their respective age-matched normal control (NC) group, the speed, but not the accuracy, of mental rotation abnormally decreased with increasing angle of orientation for patients with HD. In contrast, the accuracy, but not the speed, of rotation abnormally decreased with increasing angle of orientation for patients with AD. Additional analyses showed that these unique patterns of performance were not attributable to different speed/accuracy trade-off sensitivities. This double dissociation suggests that …