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Full-Text Articles in Psychology

Wada Test Reliability (Response To Haber Et Al.), T. Loddenkemper, H. Morris, Tara Lineweaver, C. Kellinghaus Dec 2014

Wada Test Reliability (Response To Haber Et Al.), T. Loddenkemper, H. Morris, Tara Lineweaver, C. Kellinghaus

Tara T. Lineweaver

Response piece.


Effect Of Apolipoprotein Ε4 On Hippocampal And Brain Volume In Intractable Temporal Lobe Epilepsy, Robyn Busch, Darlene Floden, Tara Lineweaver, Jessica Chapin, Kanjana Ungwongse, Tim Wehner, Ramon Diaz-Arrastia, Imad Najm Dec 2014

Effect Of Apolipoprotein Ε4 On Hippocampal And Brain Volume In Intractable Temporal Lobe Epilepsy, Robyn Busch, Darlene Floden, Tara Lineweaver, Jessica Chapin, Kanjana Ungwongse, Tim Wehner, Ramon Diaz-Arrastia, Imad Najm

Tara T. Lineweaver

This study investigated the relationship between the apolipoprotein (APOE) ε4 allele and brain volumes in patients with medically intractable temporal lobe epilepsy (TLE). MRI-based volumetric analyses of the hippocampi, cerebral hemispheres, and whole brain were conducted in 59 patients with TLE (31 with left TLE, 28 with right TLE) with hippocampal sclerosis (HS). There were no differences in hippocampal, hemispheric, or whole brain volumes as a function of ε4 status even after correcting for hemispheric and total brain volumes. However, APOE ε4 carriers showed a trend toward having a smaller discrepancy between ipsilateral and contralateral hippocampal volumes than patients without …


Memory Performance Is Related To Language Dominance As Determined By The Intracarotid Amobarbital Procedure, S. Kovac, G. Möddel, J. Reinholz, A. Alexopoulosa, T. Syed, S. Schuele, Tara Lineweaver, T. Loddenkemper Dec 2014

Memory Performance Is Related To Language Dominance As Determined By The Intracarotid Amobarbital Procedure, S. Kovac, G. Möddel, J. Reinholz, A. Alexopoulosa, T. Syed, S. Schuele, Tara Lineweaver, T. Loddenkemper

Tara T. Lineweaver

Objective

The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure.

Methods

In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other.

Results

Language lateralization and memory lateralization were positively correlated (r = 0.34, P < 0.01). Correlations differed depending on the presence and type of lesion (χ2 = 7.98, P < 0.05). LIs correlated significantly higher (z = 2.82, P < 0.05) in patients with cortical dysplasia (n = 41, r = 0.61, P < 0.01) compared with the group without lesions (n = 90, r = 0.16, P > 0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P < 0.01) and language (P …


Atypical Language Lateralization In Epilepsy Patients, Gabriel Möddel, Tara Lineweaver, Stephan Schuele, Julia Reinholz, T. Loddenkemper Dec 2014

Atypical Language Lateralization In Epilepsy Patients, Gabriel Möddel, Tara Lineweaver, Stephan Schuele, Julia Reinholz, T. Loddenkemper

Tara T. Lineweaver

Purpose:  To investigate whether atypical language dominance in epilepsy patients is related to localization and type of lesions. Methods:  Four hundred and forty-five epilepsy patients received bilateral Wada testing. Language was classified as left (L), right (R), bilateral-dependent (BD, speech arrest after left and right injections), or bilateral-independent (BI, no speech arrest after either injection). Groups were compared regarding handedness and magnetic resonance imaging (MRI) lesions. Lesions were classified as “early” (congenital), “late” neocortical (acquired after birth), and hippocampal sclerosis (HS). Results:  Of all patients, 78% were L, 6% R, 7% BD, and 9% BI. Right-handers with left lesions did …