Psychology Commons^™

Development Of The Infant Gut Microbiome Predicts Temperament Across The First Year Of Life, Molly Fox, S. Melanie Lee, Kyle S. Wiley, Venu Lagishetty, Curt A. Sandman, Jonathan P. Jacobs, Laura M. Glynn

Psychology Faculty Articles and Research

Perturbations to the gut microbiome are implicated in altered neurodevelopmental trajectories that may shape life span risk for emotion dysregulation and affective disorders. However, the sensitive periods during which the microbiome may influence neurodevelopment remain understudied. We investigated relationships between gut microbiome composition across infancy and temperament at 12 months of age. In 67 infants, we examined if gut microbiome composition assessed at 1–3 weeks, 2, 6, and 12 months of age was associated with temperament at age 12 months. Stool samples were sequenced using the 16S Illumina MiSeq platform. Temperament was assessed using the Infant Behavior Questionnaire-Revised (IBQ-R). Beta …

Childhood Trauma And Ptsd Symptoms: Disentangling The Roles Of Emotion Regulation And Distress Tolerance, Jenna E. Russo, Deepali M. Dhruve, Arazais D. Oliveros

College of Arts and Sciences Publications and Scholarship

Background: Research documents that individuals with a history of childhood trauma experience greater emotion regulation difficulties (ED), as well as lower distress tolerance (DT), two constructs that independent lines of research implicate as transdiagnostic factors in post-traumatic stress disorder (PTSD). To help elucidate how such mechanisms may influence the etiology, maintenance, and treatment of PTSD, the current study investigates the distinct mediating roles of ED and DT and explores which accounts for more unique variance.

Methods: Participants (N = 385, aged 18-48) with a childhood trauma history provided self-ratings of cumulative trauma exposure, and endorsed current ED, DT, and …