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Psychology Commons

Open Access. Powered by Scholars. Published by Universities.®

Biology

2018

Addiction

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Full-Text Articles in Psychology

Intra-Cellular Mechanisms By Which Pac1 Receptor Activation Mediates Stress-Induced Reinstatement To Drug-Seeking, Olivia Miles Jan 2018

Intra-Cellular Mechanisms By Which Pac1 Receptor Activation Mediates Stress-Induced Reinstatement To Drug-Seeking, Olivia Miles

Graduate College Dissertations and Theses

The abuse of and addiction to drugs of abuse, such as tobacco, alcohol, opioids, and illicit drugs, are growing global problems that affect the welfare of individuals and societies worldwide. The National Institute of Drug Abuse estimates the annual cost of substance abuse to be over $740 billion in costs related to drug intoxication, withdrawal and relapse. A primary challenge in the treatment of substance abuse is the tendency of users to relapse following acute or extended periods of abstinence; on average over 60% of substance abusers will return to drug use within a year of receiving treatment, many relapsing …