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Biological Psychology

Rats -- Physiology

Publication Year

Articles 1 - 5 of 5

Full-Text Articles in Psychology

Long-Term Effects Of 3,4- Methylenedioxymethamphetamine (Mdma) On Serotonergic And Dopaminergic Functioning, Jodi Lynn Kohutek Jan 2003

Long-Term Effects Of 3,4- Methylenedioxymethamphetamine (Mdma) On Serotonergic And Dopaminergic Functioning, Jodi Lynn Kohutek

Theses Digitization Project

Methylenedioxymethamphetamine (MDMA) popularly known as "Ecstasy" continues to gain popularity as a recreational drug that has been shown to increase serotonin and dopamine levels. The present study has demonstrated that repeated exposure to MDMA produces long-term damage to serotonergic and dopaminergic neurons in various regions of the rat brain.


Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole Jan 2003

Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole

Theses Digitization Project

The purpose of this study was to investigate whether a partial D₂-like dopamine agonist (i.e. terguride) would block the induction or expression of cocaine-induced behavioral sensitization in pre-weanling rats. The ability of terguride to induce behavioral sensitization was also examined, as partial D₂-like agonists have agonistic actions in cases of low dopaminergic tone.


Ultrasonic Vocalizations Of Preweanling Rats The Interaction Of K-Opioid And A₂-Noradrenergic Systems, Arbi Nazarian Jan 2000

Ultrasonic Vocalizations Of Preweanling Rats The Interaction Of K-Opioid And A₂-Noradrenergic Systems, Arbi Nazarian

Theses Digitization Project

No abstract provided.


Role Of The Dopamine D₁-Like Receptor In Amphetamine-Induced Behavioral Sensitization: A Study Using Dopamine D₁A-Receptor Deficient Mice, Patrick Eugene Karper Jan 2000

Role Of The Dopamine D₁-Like Receptor In Amphetamine-Induced Behavioral Sensitization: A Study Using Dopamine D₁A-Receptor Deficient Mice, Patrick Eugene Karper

Theses Digitization Project

The ability of the indirect dopamine agonist, amphetamine, to produce behavioral sensitization was assessed in adult D₁A-deficient and wild-type mice. It was originally predicted that : 1) dopamine (DA) D₁-like receptors are necessary for the occurrence of short- and long-term amphetamine-induced behavioral sensitization, 2) DA D₁-like receptors are necessary for environmental conditioning factors associated with amphetamine-induced behavioral sensitiazation, and 3) DA D₅ receptors are required for amphetamine-induced behavioral sensitization. Locomotor activity and sterotyped sniffing were assessed in each of three experiments.


The Effects Of Dopamine D1 And D2 Antagonists On Cocaine-Induced Cpp In Preweanling Rats, Douglas L. Pruitt Jan 1994

The Effects Of Dopamine D1 And D2 Antagonists On Cocaine-Induced Cpp In Preweanling Rats, Douglas L. Pruitt

Theses Digitization Project

The effects of dopamine D1 and D2 antagonists on conditioned place preference (CPP) and locomotor activity were assessed. A total of three experiments were conducted. In each experiment there were two conditioning days followed by a test day. The results indicate that DA D1 and D2 receptors have distictly different roles in the mediation of behavior.