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Relationships Between Adverse Childhood Experiences, Inflammation And Pain In Youth And Emerging Adults With Sickle Cell Disease, Angela Pascale
Relationships Between Adverse Childhood Experiences, Inflammation And Pain In Youth And Emerging Adults With Sickle Cell Disease, Angela Pascale
Theses and Dissertations
Sickle cell disease (SCD) is a prevalent genetic disorder involving red blood cells. SCD is a multisystem disease and is connected to various severe medical complications, including debilitating pain. Though pain and inflammation have been connected to adverse childhood experiences (ACEs) in other populations, no prior work has investigated ACEs within a SCD population. The current study examined the prevalence of ACEs as well as the association of ACEs, inflammation, and pain in a sample of youth and young adults with SCD. Utilizing the biopsychosocial model of pain, I examined individual and cumulative ACEs as possible factors relating to inflammation, …