Psychology Commons^™

Buprenorphine Effects On Anxiety-Like Behavior In B6 Mice, Megan K. Thibert

Select or Award-Winning Individual Scholarship

Buprenorphine, a semi-synthetic opioid prescribed for the treatment of opioid use disorder (OUD), has been suggested as a potential pharmacological treatment for anxiety. Some preclinical and clinical studies provide support for the anxiolytic effects of buprenorphine, but research in this area is scarce, and findings to date have been mixed. The present study was designed to test the hypothesis that buprenorphine alters anxiety-like behavior in C57BL/IJ (B6) mice measured using the elevated zero maze (EZM). Adult, male mice (n=10) were given subcutaneous injections of saline (control) and three doses of buprenorphine (0.3, 1, and 10 mg/kg). One hour following injection, …

Timing Is Everything: Temporal Dynamics Of Brain Activity Using The Human Connectome Project, Francesca Lofaro

Summer Research

Most neuroimaging studies produce snapshots of brain activity. The goal of this project is to examine the temporal dynamics of how these areas interact through time, using fear as a case study to assess how regions involved in fear interact. Working with Matlab computer code, I sort through the large fMRI dataset known as the Human Connectome Project to extract neuroimaging data from patients with different NIH Toolbox Fear-Somatic survey scores to assess the temporal dynamics between brain regions. The results will allow an understanding beyond which areas are involved, and instead will provide a picture of how these areas …

A Sociocognitive Perspective Of The Uncanny Valley, Andre Zamani

Summer Research

The “uncanny valley” is the effect of being ‘creeped out’ by things that are very close, but not quite, human (e.g., a ventriloquist dummy). Over the past two summers, I found that intranasal administrations of oxytocin, a hormone which affects attention to external social information, decreased participants’ reaction times when assessing uncanny valley stimuli, but did not affect their ratings of eeriness. Furthermore, oxytocin affected participants’ reaction times the most for stimuli rated to be intermediately eerie but altered their visual attention the most during the perception of stimuli rated to be either not eerie or very eerie. From these …

How Should Justice Policy Treat Young Offenders?, B J. Casey, Richard J. Bonnie, Andre Davis, David L. Faigman, Morris B. Hoffman, Owen D. Jones, Read Montague, Stephen J. Morse, Marcus E. Raichle, Jennifer A. Richeson, Elizabeth S. Scott, Laurence Steinberg, Kim A. Taylor-Thompson, Anthony D. Wagner

All Faculty Scholarship

The justice system in the United States has long recognized that juvenile offenders are not the same as adults, and has tried to incorporate those differences into law and policy. But only in recent decades have behavioral scientists and neuroscientists, along with policymakers, looked rigorously at developmental differences, seeking answers to two overarching questions: Are young offenders, purely by virtue of their immaturity, different from older individuals who commit crimes? And, if they are, how should justice policy take this into account?

A growing body of research on adolescent development now confirms that teenagers are indeed inherently different from adults, …

The Poverty Of The Neuroscience Of Poverty: Policy Payoff Or False Promise?, Amy L. Wax

All Faculty Scholarship

A recent body of work in neuroscience examines the brains of people suffering from social and economic disadvantage. This article assesses claims that this research can help generate more effective strategies for addressing these social conditions and their effects. It concludes that the so-called neuroscience of deprivation has no unique practical payoff, and that scientists, journalists, and policy-makers should stop claiming otherwise. Because this research does not, and generally cannot, distinguish between innate versus environmental causes of brain characteristics, it cannot predict whether neurological and behavioral deficits can be addressed by reducing social deprivation. Also, knowledge of brain mechanisms yields …

Design, Programming, And User-Experience, Kaila G. Manca

Honors Scholar Theses

This thesis is a culmination of my individualized major in Human-Computer Interaction. As such, it showcases my knowledge of design, computer engineering, user-experience research, and puts into practice my background in psychology, com- munications, and neuroscience.

I provided full-service design and development for a web application to be used by the Digital Media and Design Department and their students.This process involved several iterations of user-experience research, testing, concepting, branding and strategy, ideation, and design. It lead to two products.

The first product is full-scale development and optimization of the web appli- cation.The web application adheres to best practices. It was …

Investigating Habits: Strategies,Technologies And Models, Kyle S. Smith, Ann M. Graybiel

Dartmouth Scholarship

Understanding habits at a biological level requires a combination of behavioral observations and measures of ongoing neural activity. Theoretical frameworks as well as definitions of habitual behaviors emerging from classic behavioral research have been enriched by new approaches taking account of the identification of brain regions and circuits related to habitual behavior. Together, this combination of experimental and theoretical work has provided key insights into how brain circuits underlying action-learning and action-selection are organized, and how a balance between behavioral flexibility and fixity is achieved. New methods to monitor and manipulate neural activity in real time are allowing us to …