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Hypersensitivity Adverse Event Reporting In Clinical Cancer Trials: Barriers And Potential Solutions To Studying Severe Events On A Population Level, Christina E. Eldredge
Hypersensitivity Adverse Event Reporting In Clinical Cancer Trials: Barriers And Potential Solutions To Studying Severe Events On A Population Level, Christina E. Eldredge
Theses and Dissertations
ABSTRACT
HYPERSENSITIVITY ADVERSE EVENT REPORTING IN CLINICAL CANCER TRIALS: BARRIERS AND POTENTIAL SOLUTIONS TO STUDYING ALLERGIC EVENTS ON A POPULATION LEVEL
by
Christina Eldredge
The University of Wisconsin-Milwaukee, 2020
Under the Supervision of Professor Timothy Patrick
Clinical cancer trial interventions are associated with hypersensitivity events (HEs) which are recorded in the national clinical trial registry, ClinicalTrials.gov and publicly available. This data could potentially be leveraged to study predictors for HEs to identify at risk patients who may benefit from desensitization therapies to prevent these potentially life-threatening reactions. However, variation in investigator reporting methods is a barrier to leveraging this data …