Animal Studies Commons^™

Prevalence Of And Risk Factors For Degenerative Mitral Valve Disease In Dogs Attending Primary‐Care Veterinary Practices In England, M. Mattin, A. Boswood, D. B. Church, J. López-Alvarez, P. D. Mcgreevy, D. G. O'Neill, P. C. Thomson, D. C. Brodbelt

Epidemiology Collection

Background

To date, epidemiological studies on degenerative mitral valve disease (DMVD) in dogs have largely reported referral caseloads or been limited to predisposed breeds. Analysis of primary‐care data to identify factors associated with DMVD would help clinicians identify high‐risk individuals and improve understanding.

Objectives

To estimate the prevalence of and identify risk factors for DMVD in dogs attending primary‐care veterinary practices in England.

Animals

Cases were identified within the electronic patient records of 111,967 dogs attending 93 practices. Four hundred and 5 dogs were diagnosed with DMVD (diagnosed cases) and a further 3,557 dogs had a heart murmur (HM) consistent …

Prevalence And Risk Factors For Mast Cell Tumours In Dogs In England, Stephanie J.W. Shoop, Stephanie Marlow, David B. Church, Kate English, Paul D. Mcgreevy, Anneliese J. Stell, Peter C. Thomson, Dan G. O'Neill, David C. Brodbelt

Epidemiology Collection

Background

Mast cell tumour (MCT) appears to be a frequent tumour type in dogs, though there is little published in relation to its frequency in dogs in the UK. The current study aimed to investigate prevalence and risk factors for MCTs in dogs attending English primary-care veterinary practices.

Methods

Electronic patient records from practices participating in the VetCompass animal surveillance project between July 2007 and June 2013 were searched for MCT diagnosis. Various search terms and standard diagnostic terms (VeNom codes) identified records containing MCT diagnoses, which were evaluated against clinical criteria for inclusion to the study. MCT prevalence for …

Approaches To Canine Health Surveillance, Dan G. O'Neill, David B. Church, Paul D. Mcgreevy, Peter C. Thomson, Dave C. Brodbelt

Epidemiology Collection

Effective canine health surveillance systems can be used to monitor disease in the general population, prioritise disorders for strategic control and focus clinical research, and to evaluate the success of these measures. The key attributes for optimal data collection systems that support canine disease surveillance are representativeness of the general population, validity of disorder data and sustainability. Limitations in these areas present as selection bias, misclassification bias and discontinuation of the system respectively. Canine health data sources are reviewed to identify their strengths and weaknesses for supporting effective canine health surveillance. Insurance data benefit from large and well-defined denominator populations …

Longevity And Mortality Of Owned Dogs In England, D. G. O'Neill, D. B. Church, P. D. Mcgreevy, P. C. Thomson, D. C. Brodbelt

Epidemiology Collection

Improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity. Epidemiological research using electronic patient records (EPRs) collected from primary veterinary practices overcomes many inherent limitations of referral clinic, owner questionnaire and pet insurance data. Clinical health data from 102,609 owned dogs attending first opinion veterinary practices (n = 86) in central and southeast England were analysed, focusing on 5095 confirmed deaths.

Of deceased dogs with information available, 3961 (77.9%) were purebred, 2386 (47.0%) were female, 2528 (49.8%) were neutered and 1105 (21.7%) were insured. The overall median longevity was 12.0 years …

Canine Chronic Kidney Disease In Uk Veterinary Practices: Prevalence, Risk Factors And Survival, D. G. O'Neill, J. Elliott, D. B. Church, P. D. Mcgreevy, P. C. Thomson, D. C. Brodbelt

Epidemiology Collection

Analyses covering 107,214 dogs attending 89 UK practices aimed to estimate the prevalence and identify risk factors associated with canine chronic kidney disease (CKD) diagnosis and survival. The apparent prevalence (AP) was estimated using a cross-sectional approach while the true prevalence (TP) was estimated using Bayesian analysis. A nested case-control study design was used to evaluate risk factors. Survival analysis was conducted using the Kaplan-Meier survival curve method and multivariable Cox proportional hazards regression modelling. CKD AP was estimated at 0.21% and TP at 0.37%. CKD risk factors included increasing age, being insured and certain breeds. The median survival time …