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Articles 1 - 2 of 2
Full-Text Articles in Animal Studies
Long-Term Effects Of Early Social Isolation In Macaca Mulatta: Changes In Dopamine Receptor Function Following Apomorphine Challenge, Mark H. Lewis, John P. Gluck, Tom L. Beauchamp, Michael F. Keresztury, Richard B. Mailman
Long-Term Effects Of Early Social Isolation In Macaca Mulatta: Changes In Dopamine Receptor Function Following Apomorphine Challenge, Mark H. Lewis, John P. Gluck, Tom L. Beauchamp, Michael F. Keresztury, Richard B. Mailman
Experimentation Collection
The hypothesis that early social isolation results in long-term alterations in dopamine receptor sensitivity was tested using older adult rhesus monkeys. Isolated and control monkeys were challenged with apomorphine (0.1 and 0.3 mg/kg), and the drug effects on spontaneous blink rate, stereotyped behavior, and self-injurious behavior were quantified using observational measures. Monoamine metabolites were quantified from cisternal CSF by HPLC-EC, prior to pharmacological challenge. Isolated and control monkeys did not differ in CSF concentrations of HVA, 5-HIAA, or MHPG. At the higher dose, apomorphine significantly increased the rate of blinking, the occurrence of whole-body stereotypies, and the intensity of stereotyped …
The Live Sheep Export Industry, Richard Norris, Barry Richards, Tony Higgs
The Live Sheep Export Industry, Richard Norris, Barry Richards, Tony Higgs
Journal of the Department of Agriculture, Western Australia, Series 4
Australia's live sheep trade to Middle Eastern countries is an important export industry. However, about 2 per cent of the sheep die, mainly during the sea voyage. The Western Australian Department of Agriculture has conducted a major research programme to improve the health and welfare of sheep during live export. The programme has'examined many aspects of the export sheep industry, and a substantial part of it has focused on why sheep die during sea transport.