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Full-Text Articles in Animal Studies

A Monte Carlo Simulation Of Rat Choice Behavior With Interdependent Outcomes, Michelle A. Frankot Jan 2022

A Monte Carlo Simulation Of Rat Choice Behavior With Interdependent Outcomes, Michelle A. Frankot

Graduate Theses, Dissertations, and Problem Reports

Preclinical behavioral neuroscience often uses choice paradigms to capture psychiatric symptoms. In particular, the subfield of operant research produces nested datasets with many discrete choices in a session. The standard analytic practice is to aggregate choice into a continuous variable and analyze using ANOVA or linear regression. However, choice data often have multiple interdependent outcomes of interest, violating an assumption of general linear models. The aim of the current study was to quantify the accuracy of linear mixed-effects regression (LMER) for analyzing data from a 4-choice operant task called the Rodent Gambling Task (RGT), which measures decision-making in the context …


Jackpot Reinforcers And The Operant Behavior Of Siamese Fighting Fish (Betta Splendens), Jackson Carter Fox Jan 2021

Jackpot Reinforcers And The Operant Behavior Of Siamese Fighting Fish (Betta Splendens), Jackson Carter Fox

Capstones and Honors Theses

Jackpot reinforcers are an intriguing yet seldom studied area of operant conditioning with many potential applications in the scope of behavioral research. In this study, two Siamese fighting fish (Betta s.) were presented with the visual stimulus of a mirror upon completion of a target response, providing the opportunity to display an agonistic behavior towards their own mirror image. This opportunity for agonistic display to the mirror served as the primary reinforcer of the target response, which was simply swimming in a particular direction over a bar suspended in the center of the tank. This over-the-bar swimming was …


Probability Discounting Of Lewis And Fischer 344 Rats: Strain Comparisons At Baseline And Following Acute Administration Of D-Amphetamine, Jenny E. Ozga Jan 2019

Probability Discounting Of Lewis And Fischer 344 Rats: Strain Comparisons At Baseline And Following Acute Administration Of D-Amphetamine, Jenny E. Ozga

Graduate Theses, Dissertations, and Problem Reports

Risky choice can be defined as choice for a larger, uncertain reinforcer over a smaller, certain reinforcer when choosing the smaller alternative maximizes reinforcement. Risky choice is studied using various procedures in the animal laboratory; one such procedure is called probability discounting. There are many variables that contribute to risky decision-making, including biological and pharmacological determinants. The present study assessed both of these variables by evaluating dose-response effects of d-amphetamine on risky choice of Lewis (LEW) and Fischer 344 (F344) rats. The probability-discounting procedure included discrete-trials choices between one food pellet delivered 100% of the time and three food …