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Journal Articles

William E. Price

Articles 1 - 11 of 11

Full-Text Articles in Social and Behavioral Sciences

Air-Drying Of Banana: Influence Of Experimental Parameters, Slab Thickness, Banana Maturity And Harvesting Season, Minh-Hue Nguyen, William E. Price Oct 2012

Air-Drying Of Banana: Influence Of Experimental Parameters, Slab Thickness, Banana Maturity And Harvesting Season, Minh-Hue Nguyen, William E. Price

William E. Price

Air-drying of banana slabs has been investigated and the influence of experimental parameters such as temperature, relative humidity and slab thickness has been studied. This was in part re-investigated because of inconsistencies in previous studies, particularly in relation to derived water diffusion coefficients. In addition, it is shown that harvest season and hence initial moisture content has a very marked influence on the drying kinetics. By contrast banana maturity (ripeness) has little influence on the kinetics despite there being significant differences in morphology and chemical composition between green and ripe bananas. The effect of these two variables on the drying …


Increased Probiotic Yogurt Or Resistant Starch Intake Does Not Affect Isoflavone Bioavailability In Subjects Consuming A High Soy Diet, Theresa A. Larkin, William E. Price, Lee B. Astheimer Oct 2012

Increased Probiotic Yogurt Or Resistant Starch Intake Does Not Affect Isoflavone Bioavailability In Subjects Consuming A High Soy Diet, Theresa A. Larkin, William E. Price, Lee B. Astheimer

William E. Price

Objective: Probiotics and prebiotics that affect gut microflora balance and its associated enzymeactivity may contribute to interindividual variation in isoflavone absorption after soy intake, possiblyenhancing isoflavone bioavailability. This study examined the effects of the consumption ofbioactive yogurt (a probiotic) or resistant starch (a known prebiotic) in combination with high soyintake on soy isoflavone bioavailability.Methods: Using a crossover design, chronic soy consumption was compared with soy plusprobiotic yogurt or resistant starch in older male and postmenopausal females (n 31). Isoflavonebioavailability was assessed at the beginning and end of each 5-wk dietary period by samplingplasma and urine after a standardized soy meal.Results: …


Fractionation Of Sedimentary Arsenic From Port Kembla Harbour, Nsw, Australia, Glennys A. O'Brien, William E. Price, Bryan E. Chenhall, Muhammad Damris Oct 2012

Fractionation Of Sedimentary Arsenic From Port Kembla Harbour, Nsw, Australia, Glennys A. O'Brien, William E. Price, Bryan E. Chenhall, Muhammad Damris

William E. Price

The binding of arsenic in sediments of the heavily industrialised Port Kembla Harbour, NSW, Australia, has been investigated. Both dredge and core samples have been used to develop a sieving/sequential extraction (SE) procedure. Dredge samples included oxic surficial and deeper anoxic sediment. The main core sample analysed was 18 cm deep, sliced at 2 cm intervals. Sediment was sieved to three size ranges (250 microm) and each of these was then subjected to a four step SE, sequentially solubilizing arsenic as ion exchangeable, 1 M HCl soluble, NH(2)OH.HCl soluble, and strong oxidising acid soluble. Concentrations of 50-500 mg As kg(-1) …


A Fragmentation Study Of Isoflavones In Negative Electrospray Ionization By Msn Ion Trap Mass Spectrometry And Triple Quadrupole Mass Spectrometry, Jinguo Kang, Larry A. Hick, William E. Price Oct 2012

A Fragmentation Study Of Isoflavones In Negative Electrospray Ionization By Msn Ion Trap Mass Spectrometry And Triple Quadrupole Mass Spectrometry, Jinguo Kang, Larry A. Hick, William E. Price

William E. Price

This study has elucidated the fragmentation pathway for deprotonated isoflavones in electrospray ionization using MSn ion trap mass spectrometry and triple quadrupole mass spectrometry. Genistein-d4 and daidzein-d3 were used as references for the clarification of fragment structures. To confirm the relationship between precursor and product ions, some fragments were traced from MS2 to MS5. The previous literature for the structurally related flavones and flavanones located the loss of ketene (C2H2O) to ring C, whereas the present fragmentation study for isoflavones has shown that the loss of ketene occurs elsewhere at ring A. In the further fragmentation of the [M-H-CH3]•- radical …


Tissue Distribution Of Lignans In Rats In Response To Diet, Dose-Response, And Competition With Isoflavones, Timothy Murray, J. Kang, Lee Astheimer, William E. Price Oct 2012

Tissue Distribution Of Lignans In Rats In Response To Diet, Dose-Response, And Competition With Isoflavones, Timothy Murray, J. Kang, Lee Astheimer, William E. Price

William E. Price

This paper investigates the occurrence and distribution of the lignan metabolites enterodiol (END) and enterolactone (ENL) and the isoflavone daidzein (DAID) in rat tissues using liquid chromatography - electrospray ionisation mass spectrometry (LC – ESI/MSn) following a variety of dietary regimes. Further, we examined the dose-response and distribution of END and ENL in liver, testes, prostate and lung, and investigated the effects of competition between lignans and isoflavones on metabolite distribution. In liver, testes, prostate & lung tissue, dose related increases in END concentration were observed. In the testes, the co-administration of 60 mg/kg SDG with 60 mg/kg isoflavones produced …


Effect Of Organic Solvents On The Separation Of Benzoic Acids By Capillary Electrophoresis, Young J. Lee, William E. Price, Margaret Sheil Oct 2012

Effect Of Organic Solvents On The Separation Of Benzoic Acids By Capillary Electrophoresis, Young J. Lee, William E. Price, Margaret Sheil

William E. Price

The effect of organic modifiers on the separation of a number of closely related isomeric benzoic acids by capillary electrophoresis is described. It is shown that while a single modifier concentration cannot help resolve the entire electropherogram, organic modifiers do significantly enhance the resolution of parts of the separation system by comparison with 40 mmol l-1 phosphate buffer. The effects on separation and retention times are discussed in terms of the effects on electroosmotic flow and the electrophoretic mobilities of the charged solutes. The effects were found to be modifier specific, although the trends were in the same direction (ie., …


Occurrence Of Phytoestrogens In Municipal Wastewater And Surface Waters, Jinguo Kang, William E. Price Oct 2012

Occurrence Of Phytoestrogens In Municipal Wastewater And Surface Waters, Jinguo Kang, William E. Price

William E. Price

Phytoestrogens (isoflavones, enterolignans and coumestrol) in wastewater samples and surface water samples have been analysed by LC-ESI-MSn. In wastewater samples, high levels of enterolactone (581 – 2111 ng/L), daidzein (341 – 1688 ng/L) and enterodiol (60 – 834 ng/L) were detected in raw sewage, but the vast majority of the analysed phytoestrogens were removed effectively in treatment process. The removal rates of the analysed phytoestrogens in the two advanced tertiary treatment plants were > 99%; a case study in one of the treatment plants showed that most of the residual phytoestrogens were removed by biological treatment using activated sludge. In surface …


Corrigendum To ‘‘The Chaperone Action Of Bovine Milk As1- And As2-Caseins And Their Associated Form As-Casein’’ [Arch. Biochem. Biophys. 510 (2011) 42–52], Teresa M. Treweek, David C. Thorn, William E. Price, John A. Carver Oct 2012

Corrigendum To ‘‘The Chaperone Action Of Bovine Milk As1- And As2-Caseins And Their Associated Form As-Casein’’ [Arch. Biochem. Biophys. 510 (2011) 42–52], Teresa M. Treweek, David C. Thorn, William E. Price, John A. Carver

William E. Price

No abstract provided.


The Effect Of Dextran On Subunit Exchange Of Αa-Crystallin, A. Ghahghaei, A. Rekas, W. E. Price, J. A. Carver Oct 2012

The Effect Of Dextran On Subunit Exchange Of Αa-Crystallin, A. Ghahghaei, A. Rekas, W. E. Price, J. A. Carver

William E. Price

α-Crystallin, a member of small heat shock protein (sHsp) family, is comprised of αA and αB subunits and acts as a molecular chaperone by interacting with unfolding proteins to prevent their aggregation. The αA-crystallin homopolymer consists of 30-40 subunits that are undergoing dynamic exchange. α-Crystallin and αA-crystallin are poorer chaperones in the presence of the crowding agent, dextran. Using fluorescence resonance energy transfer, it is shown that the αAcrystallin subunit exchange rate strongly increased with temperature. Binding of reduced ovotransferrin to αA-crystallin markedly decreases the rate of subunit exchange, as does the presence of dextran. In addition, in the presence …


The Key Importance Of Soy Isoflavone Bioavailability To Understanding Health Benefits, T. A. Larkin, William E. Price, L. Astheimer Oct 2012

The Key Importance Of Soy Isoflavone Bioavailability To Understanding Health Benefits, T. A. Larkin, William E. Price, L. Astheimer

William E. Price

Research over the past two decades has provided significant epidemiological and other evidence for the health benefits of the consumption of soy-based foods. A large number of dietary intervention studies have examined the effects of soy isoflavones on risk factors for cardiovascular disease and hormone-dependent cancers. However, these report large variability in outcome measures, very limited reproducibility between studies and in some cases, controversy between results of clinical trials using dietary soy or soy protein and isoflavone supplementation. This highlights a major gap in our understanding of soy isoflavone uptake, metabolism, distribution, and overall bioavailability. There are many potential factors …


Using Calibration Approaches To Compensate For Remaining Matrix Effects In Quantitative Liquid Chromatography Electrospray Ionization Multistage Mass Spectrometric Analysis Of Phytoestrogens In Aqueous Environmental Samples, Jinguo Kang, Larry A. Hick, William E. Price Oct 2012

Using Calibration Approaches To Compensate For Remaining Matrix Effects In Quantitative Liquid Chromatography Electrospray Ionization Multistage Mass Spectrometric Analysis Of Phytoestrogens In Aqueous Environmental Samples, Jinguo Kang, Larry A. Hick, William E. Price

William E. Price

Signal suppression is a common problem in quantitative LC-ESI-MSn analysis in environment samples, especially in highly loaded wastewater samples with highly complex matrix. Optimization of sample preparation and improvement of chromatographic separation are prerequisite to improve reproducibility and selectivity. Matrix components may be reduced if not eliminated by a series of sample preparation steps. However, extensive sample preparation can be time-consuming and risk the significant loss of some trace analytes. The best way to further compensate matrix effects is the use of internal standard for each analyte. However, in a multi-component analysis, finding appropriate internal standards for every analyte is …