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Benzodiazepines

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Full-Text Articles in Social and Behavioral Sciences

Three Essays In Health Economics, Mir Nahid Mahmud Aug 2022

Three Essays In Health Economics, Mir Nahid Mahmud

Legacy Theses & Dissertations (2009 - 2024)

This dissertation comprises three empirical essays. The first essay estimates the long-term health and socioeconomic impact of early life nutritional deficit using the Bangladesh Famine from 1974-1975 as a natural experiment. The second essay investigates if pubic health insurance coverage of “ immigrant children¬” changed as a result of the lift of the “five-year-ban” in the Children Health Insurance Reauthorization Act-2009. The final chapter estimates the relationship between child health conditions and maternal employment using conventional econometric models. To expand the analysis and contribute to the literature, I estimate the relationship by implementing a Multiple Indicator Multiple Causes Model (MIMIC).


Three Essays In Health Economics, Savita Ramaprasad Aug 2022

Three Essays In Health Economics, Savita Ramaprasad

Legacy Theses & Dissertations (2009 - 2024)

This dissertation includes three essays in applied econometrics. Each essay involves using econometric and statistical techniques to draw inferences from observational data on the effect of policies and quasi-experiments on various outcomes of social importance.


Three Essays In Health Economics, Sai Sindhura Gundavarapu Aug 2022

Three Essays In Health Economics, Sai Sindhura Gundavarapu

Legacy Theses & Dissertations (2009 - 2024)

This thesis explores factors that influence various healthcare professions, and their practice behaviors. The first chapter focuses on the impacts of occupational regulation of optometrists. The second and third chapters examine the role of education and practice environment on the prescribing behavior of specialist physicians.


Three Essays In Health Economics, Jun Soo Lee Aug 2022

Three Essays In Health Economics, Jun Soo Lee

Legacy Theses & Dissertations (2009 - 2024)

My dissertation includes three main studies: the first study examines the seasonality of the birth weight and the underlying mechanisms for the seasonality; the second study documents the impact of weather conditions on the gestation period by using the duration analysis and on the birth weight by using the decomposition method and quantile regression; the third study analyzes the effects of density of immigrant population around place of residence on the residents’ health outcomes.In the first study, we evaluate a range of plausible mechanisms that may underlie the seasonality of the birth weight by using U.S. birth certificate records from …


Benzodiazepine Use And Dependence In Relation To Chronic Pain Intensity And Pain Catastrophizing, Emma Carnes Lape Dec 2021

Benzodiazepine Use And Dependence In Relation To Chronic Pain Intensity And Pain Catastrophizing, Emma Carnes Lape

Theses - ALL

Benzodiazepines (BZDs), a class of sedative-hypnotic drugs, are at the center of an emerging prescription drug crisis. From approximately 1995-2015, overdose deaths involving BZDs quadrupled and average dose equivalents more than tripled. Specific concern has centered on elevated rates of BZD use among individuals with chronic pain, given that BZDs are generally not indicated for pain management. Consistent with negative reinforcement and motivational models of substance use, desire for pain alleviation may be a salient motivator of BZD use, particularly as individuals commonly report using BZDs for negative affect alleviation. The present study tested cross-sectional associations between pain intensity and …


Regulation Of Gabaa Receptor Subunit Expression In Substance Use Disorders, Jeffrey S. Barker, Rochelle M. Hines Jun 2020

Regulation Of Gabaa Receptor Subunit Expression In Substance Use Disorders, Jeffrey S. Barker, Rochelle M. Hines

Psychology Faculty Research

The modulation of neuronal cell firing is mediated by the release of the neurotransmitter GABA (γ-aminobuytric acid), which binds to two major families of receptors. The ionotropic GABAA receptors (GABAARs) are composed of five distinct subunits that vary in expression by brain region and cell type. The action of GABA on GABAARs is modulated by a variety of clinically and pharmacologically important drugs such as benzodiazepines and alcohol. Exposure to and abuse of these substances disrupts homeostasis and induces plasticity in GABAergic neurotransmission, often via the regulation of receptor expression. Here, we review the regulation of GABAAR subunit expression in …


Physician Training And Support In Managing Dilemmas Around Benzodiazepine Prescribing, Elizabeth Corley Jan 2020

Physician Training And Support In Managing Dilemmas Around Benzodiazepine Prescribing, Elizabeth Corley

Antioch University Full-Text Dissertations & Theses

Numerous concerns have emerged regarding the dangers of extended benzodiazepine use and abuse, as well as continued prescribing by medical professionals despite related contraindications. Primary care physicians (PCPs) may find decisions around benzodiazepine prescription and related patient encounters to be especially challenging. Little is known on the efficacy of routine medical training and supervision/consultation models in preparing emerging PCPs for managing the dilemmas that may ensue with regards to prescribing benzodiazepines. The present study sought to begin addressing this gap by conducting an initial qualitative inquiry into the training and supervision experiences and needs of a group of current family …


Drug Overdose Prevention: Needs Of Healthcare Professionals And First Responders, Jessica Groeneweg, Lynn Castrianno, Gaylene Armstrong, Jeanette Harder, Rachel Lubischer, Dawne Frain Aug 2019

Drug Overdose Prevention: Needs Of Healthcare Professionals And First Responders, Jessica Groeneweg, Lynn Castrianno, Gaylene Armstrong, Jeanette Harder, Rachel Lubischer, Dawne Frain

Jeanette Harder

Purpose and Background
The Nebraska Department of Health and Human Services (DHHS) partnered with Support and Training for the Evaluation of Programs (STEPs) at the University of Nebraska at Omaha, Grace Abbott School of Social Work, to complete a statewide needs assessment between October 2018 and April 2019. The purpose of this needs assessment was to gauge the capacity of statewide systems in Nebraska to respond to surges or clusters of intentional, unintentional, and unknown drug overdoses, especially in high-burden areas and with a focus on opioids. The hope of the results from this needs assessment is to inform DHHS …


Method Development And Validation For The Determination Of Designer Benzodiazepines In Blood By Lc-Ms/Ms, Victoria Mei Jun 2019

Method Development And Validation For The Determination Of Designer Benzodiazepines In Blood By Lc-Ms/Ms, Victoria Mei

Student Theses

The misuse of designer benzodiazepines, as an alternative to prescription benzodiazepines and for drug-facilitated sexual assaults, has emerged as a growing threat, due in part to the ease of purchasing these drugs on the internet at low prices. Causing concern for safety, is the lack of dosage information resulting in users self-medicating, often leading to unintended overdoses, coma, or death at higher doses. With limited published data regarding quantification of designer benzodiazepines in forensic cases, a method was validated for the determination of thirteen and screening for two designer benzodiazepines in blood, in addition to a limited number of common …


The Effect Of The Implementation Of A Quarterly Triad Tool In The Pain Clinic Setting On The Assessment And Mitigation Of Risks In Patients On Chronic Opioid Therapy, Caroline Asava May 2019

The Effect Of The Implementation Of A Quarterly Triad Tool In The Pain Clinic Setting On The Assessment And Mitigation Of Risks In Patients On Chronic Opioid Therapy, Caroline Asava

Evidence-Based Practice Project Reports

The concurrent use of opioids and benzodiazepines (BZDs poses a formidable challenge for clinicians who manage chronic pain. While the escalating use of opioid analgesics for the treatment of chronic pain and the concomitant rise in opioid-related abuse and misuse are widely recognized trends, the contribution of combination use of BZDs, alcohol, and/or other sedative agents to opioid-related morbidity and mortality is underappreciated, even when these agents are used appropriately. Patients with chronic pain who use opioid analgesics along with BZDs have a defined increase in rates of adverse events, overdose, and death, warranting close monitoring. To improve patient outcomes, …


Drug Overdose Prevention: Needs Of Healthcare Professionals And First Responders, Jessica Groeneweg, Lynn Castrianno, Gaylene Armstrong, Jeanette Harder, Rachel Lubischer, Dawne Frain Apr 2019

Drug Overdose Prevention: Needs Of Healthcare Professionals And First Responders, Jessica Groeneweg, Lynn Castrianno, Gaylene Armstrong, Jeanette Harder, Rachel Lubischer, Dawne Frain

Reports

Purpose and Background
The Nebraska Department of Health and Human Services (DHHS) partnered with Support and Training for the Evaluation of Programs (STEPs) at the University of Nebraska at Omaha, Grace Abbott School of Social Work, to complete a statewide needs assessment between October 2018 and April 2019. The purpose of this needs assessment was to gauge the capacity of statewide systems in Nebraska to respond to surges or clusters of intentional, unintentional, and unknown drug overdoses, especially in high-burden areas and with a focus on opioids. The hope of the results from this needs assessment is to inform DHHS …


Comorbid Substance Use Diagnoses And Partner Violence Among Offenders Receiving Pharmacotherapy For Opioid Dependence, Cory A. Crane, Robert C. Schlauch, Susan Devine, Caroline J. Easton Jan 2016

Comorbid Substance Use Diagnoses And Partner Violence Among Offenders Receiving Pharmacotherapy For Opioid Dependence, Cory A. Crane, Robert C. Schlauch, Susan Devine, Caroline J. Easton

Psychology Faculty Publications

While previous studies find mixed evidence of an association between opioid use and intimate partner violence perpetration among community samples, initial evidence has detected increased rates of partner violence among individuals receiving pharmacological intervention for opioid dependence. The current study evaluated the role of current comorbid substance use diagnoses, a robust risk factor for violent behavior, on the likelihood of perpetrating partner violence among a high risk sample of offenders receiving pharmacological intervention for opioid dependence. The authors analyzed self-report data provided by 81 (55 male) opioid dependent offenders during a court-ordered substance use interview. Approximately one-third of the sample …


Diffusion Of Innovative Panic Disorder Treatment Strategies In A Community Mental Heath Agency, Whitney Noelle Pierce Jan 2013

Diffusion Of Innovative Panic Disorder Treatment Strategies In A Community Mental Heath Agency, Whitney Noelle Pierce

Browse all Theses and Dissertations

This translational research piece involved collaborating with a local community mental health agency to examine knowledge, skills, attitudes, practices, and outcomes for panic disorder treatments. The project included designing and administering an online survey to client care personnel including psychologists, counselors, social workers, nurses, and psychiatrists. Additionally, a database review was utilized to obtain information about treatment modalities, duration, and outcomes. Survey results were analyzed using goodness of fit statistics to show differences between attitudes of participants by discipline regarding the safety and effectiveness of panic disorder treatments. The database analysis of pre and post GAF scores revealed comparable outcomes …


Potential Adverse Consequences Of Benzodiazepines In Older Adults, University Of Maine Center On Aging Jan 2003

Potential Adverse Consequences Of Benzodiazepines In Older Adults, University Of Maine Center On Aging

Maine Center on Aging Research and Evaluation

There are many potential negative consequences that come with Benzodiazepine usage in older adults. These include neuropsychological effects (e.g., cognitive impairments and psychomotor impairments), physiological and psychological dependence, and withdrawal symptoms. It is important to become properly educated on the effects of these drugs and to communicate with a doctor.


Benzodiazepines And You, University Of Maine Center On Aging Jan 2003

Benzodiazepines And You, University Of Maine Center On Aging

Maine Center on Aging Research and Evaluation

Benzodiazepines are a group of commonly prescribed drugs utilized to manage anxiety, sleep problems, symptoms of alcohol withdrawal, or as a muscle relaxant. Older adults are a common population to be prescribed these drugs, and the prescriptions often come in inappropriate amounts. Long term use of Benzodiazepines increases the risk of negative side effects, such as addiction, misuse, memory loss, and falls. It is important to discuss these factors with your health care provider and to discuss possible alternatives.


The Treatment Of Hypnotic Dependent Sleep Disorder: A Case Study, Theodore V. Cooper, K. L. Lichstein, N. Aguillard Jan 2003

The Treatment Of Hypnotic Dependent Sleep Disorder: A Case Study, Theodore V. Cooper, K. L. Lichstein, N. Aguillard

Theodore V. Cooper

No abstract provided.