Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 2 of 2
Full-Text Articles in Social and Behavioral Sciences
Twin Gestation And Neuropsychological Outcome Of Preschool Age Children Born Prematurely, Jamie Christine Piercy
Twin Gestation And Neuropsychological Outcome Of Preschool Age Children Born Prematurely, Jamie Christine Piercy
Wayne State University Theses
Multiples are thought to be at increased risk for developmental outcome deficits in the preschool years, following preterm birth. However, little research has been conducted to determine whether this group remains at higher risk in the age of artificial reproductive techniques and the modern NICU. The purpose of this study was to investigate whether multiplicity is a risk factor for neuropsychological outcome deficits in a sample of 118 preschoolers (49 multiples, 75 singletons) born prematurely (<34 weeks gestation). As predicted, there were significant relationships between multiplicity and outcome measures, however, the direction of the effects were opposite to our prediction, with multiplies demonstrating superior performance. Additionally, significant multiplicity by sex interactions revealed a female twin advantage over male twin and singleton performance. In this preschool age sample, preterm multiples were not at a disadvantage when compared to singleton counterparts, demonstrating either equivalent or superior neuropsychological performance.
Antidepressant Medications And Cognitive Functioning In Major Depressive Disorder, Rachel Kay
Antidepressant Medications And Cognitive Functioning In Major Depressive Disorder, Rachel Kay
Wayne State University Theses
Individuals with Major Depressive Disorder (MDD) frequently experience cognitive decrements in addition to mood impairments. Ironically, antidepressant medications used to treat depression may have adverse effects on cognitive functioning. It is imperative to understand the relative cognitive costs of antidepressants when considering the treatment of MDD patients. Furthermore, observational studies of depression are challenged by problems of systematically confounded variables. Researchers are often faced with difficulties in managing this issue and opt to either ignore the problem, alter their sample, or use inappropriate statistical methods (e.g., Analysis of Covariance) due to a limited understanding of acceptable solutions. It is important …