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Full-Text Articles in Social and Behavioral Sciences

Performance Evaluation Of Intermittently Cfrp Wrapped Square And Circularised Square Reinforced Concrete Columns Under Different Loading Conditions, Anh Duc Mai, M Neaz Sheikh, Muhammad N. S Hadi Jan 2019

Performance Evaluation Of Intermittently Cfrp Wrapped Square And Circularised Square Reinforced Concrete Columns Under Different Loading Conditions, Anh Duc Mai, M Neaz Sheikh, Muhammad N. S Hadi

Faculty of Engineering and Information Sciences - Papers: Part B

This paper presents the results of an experimental investigation on square and circularised square rein-forced concrete (RC) columns intermittently wrapped with carbon fibre reinforced polymer (CFRP)under different loading conditions. Twelve RC specimens consisting of eight square RC specimenswith 150mm150mm cross-section and 800mm height and four circularised square RC specimenswith 212mm diameter and 800 mm height were tested under concentric axial load, eccentric axialload and four-point flexural load. The test results showed that intermittent wrapping increased thestrength and ductility of square RC specimens. The test results also showed that circularisation com-bined with intermittent wrapping significantly improved the strength and ductility of …


Exploring Approaches To Dietetic Assessment Of A Common Task Across Different Universities Through Assessment Moderation, Claire Palermo, E Volders, S Gibson, Meredith A. Kennedy, A Wray, J Thomas, Mary Hannan-Jones, Danielle Gallegos, Eleanor J. Beck Jan 2018

Exploring Approaches To Dietetic Assessment Of A Common Task Across Different Universities Through Assessment Moderation, Claire Palermo, E Volders, S Gibson, Meredith A. Kennedy, A Wray, J Thomas, Mary Hannan-Jones, Danielle Gallegos, Eleanor J. Beck

Faculty of Science, Medicine and Health - Papers: part A

Background: Assessment presents one of the greatest challenges to evaluating health professional trainee performance, as a result of the subjectivity of judgements and variability in assessor standards. The present study aimed to test a moderation procedure for assessment across four independent universities and explore approaches to assessment and the factors that influence assessment decisions. Methods: Assessment tasks designed independently by each of the four universities to assess student readiness for placement were chosen for the present study. Each university provided four student performance recordings for moderation. Eight different academic assessors viewed the student performances and assessed them using the corresponding …


Rediscovering Why I Do What I Do: The Benefits Of Explaining Ergonomics To Researchers From Different Disciplines - A Personal Reflection On A Phd Journey, Alison F. Bell Jan 2017

Rediscovering Why I Do What I Do: The Benefits Of Explaining Ergonomics To Researchers From Different Disciplines - A Personal Reflection On A Phd Journey, Alison F. Bell

Faculty of Social Sciences - Papers (Archive)

Abstract presented at the HFESA 52nd Annual Conference, 26-29 November 2017, Wollongong, Australia


Experimental Study On Frp Tube Reinforced Concrete Columns Under Different Loading Conditions, Weiqiang Wang, M Neaz Sheikh, Muhammad N. S Hadi Jan 2016

Experimental Study On Frp Tube Reinforced Concrete Columns Under Different Loading Conditions, Weiqiang Wang, M Neaz Sheikh, Muhammad N. S Hadi

Faculty of Engineering and Information Sciences - Papers: Part A

The behavior of fiber-reinforced polymer (FRP) tube reinforced concrete (FTRC) columns under different loading conditions was investigated in this study. Four groups of 16 specimens were cast and tested. Specimens in the first group (the reference group) were re- inforced with longitudinal steel bars and steel helices (Group REF). Specimens in the second group were reinforced with intact glass FRP tubes (Group IT). Specimens in the third group were also reinforced with intact glass FRP tubes. In addition, polymer grid was embedded into the concrete cover to reduce the cover spalling (Group ITG). Specimens in the fourth group were reinforced …


Wearable Vibrotactile Biofeedback Device Allowing Identification Of Different Floor Conditions For Lower-Limb Amputees, Anson Wan, Duo Wong, Christina Ma, Ming Zhang, Winson Lee Jan 2016

Wearable Vibrotactile Biofeedback Device Allowing Identification Of Different Floor Conditions For Lower-Limb Amputees, Anson Wan, Duo Wong, Christina Ma, Ming Zhang, Winson Lee

Faculty of Engineering and Information Sciences - Papers: Part A

Objective

To evaluate a newly developed biofeedback device enabling lower-limb amputees to identify various floor conditions.

Design

Self-control with repeated measures (with and without the biofeedback device) within the amputee group, and group control comparing between amputee and nonamputee groups.

Setting

University locomotion laboratory.

Participants

Five lower-limb amputees and 8 nonamputees (N=13).

Interventions

A wearable biofeedback device, which identified different floor conditions by analyzing the force patterns under the prosthetic feet and provided vibration cues in response to different floor conditions, was provided to the amputees.

Main Outcome Measures

The subjects stepped on a foam platform concealing a small object …


Defining Problematic Pharmaceutical Opioid Use Among People Prescribed Opioids For Chronic Noncancer Pain: Do Different Measures Identify The Same Patients?, Gabrielle Campbell, Raimondo Bruno, Nicholas Lintzeris, Milton Cohen, Suzanne Nielsen, Wayne Hall, Briony K. Larance, Richard P. Mattick, Fiona Blyth, Michael P. Farrell, Louisa Degenhardt Jan 2016

Defining Problematic Pharmaceutical Opioid Use Among People Prescribed Opioids For Chronic Noncancer Pain: Do Different Measures Identify The Same Patients?, Gabrielle Campbell, Raimondo Bruno, Nicholas Lintzeris, Milton Cohen, Suzanne Nielsen, Wayne Hall, Briony K. Larance, Richard P. Mattick, Fiona Blyth, Michael P. Farrell, Louisa Degenhardt

Faculty of Social Sciences - Papers (Archive)

The International Classification of Diseases (ICD) and the Diagnostic and Statistical Manual (DSM) are routinely used in diagnosing illicit substance use disorders, but for people taking prescribed opioids they remain controversial. In pain medicine, the concept of "Addiction" is preferred with reduced emphasis on tolerance and withdrawal. This article examines the prevalence and characteristics of pharmaceutical opioid dependence/disorder according to ICD, DSM, and the pain medicine concept of "Addiction," among chronic noncancer pain (CNCP) patients prescribed opioids. In the current study, we used data from a national sample of 1134 people prescribed opioids for CNCP. Past 12-month "Addiction" (based on …


Same But Different: Sources Of Natural Resource Management Advice For Lifestyle Oriented Rural Landholders, Victoria Ikutegbe, Nicholas J. Gill, Peter Klepeis Jan 2015

Same But Different: Sources Of Natural Resource Management Advice For Lifestyle Oriented Rural Landholders, Victoria Ikutegbe, Nicholas J. Gill, Peter Klepeis

Faculty of Social Sciences - Papers (Archive)

Amenity migration to attractive and accessible non-metropolitan areas changes social and environmental relations with consequences for natural resource management and landscape composition and trajectories. Lifestyler oriented rural landholders are often cast as a problem for land management and extension. Managers and some researchers see them as a cause of landscape and social fragmentation and report difficulties in engaging such landowners on natural resource management issues and responsibilities. In contrast, limited existing research indicates that lifestylers do join and form networks of personal and other contacts for advice and support in land management. We contribute to this research with a survey …


A Study Of Self-Determined Motivation Toward Physical Education Among Different Levels Of Schooling, Dana J. Perlman Jan 2015

A Study Of Self-Determined Motivation Toward Physical Education Among Different Levels Of Schooling, Dana J. Perlman

Faculty of Social Sciences - Papers (Archive)

Educational research is continously examining the changes and progress of students throughout their educational career. Understanding student change is a critical element in creating learning settings that can meet the diverse needs of students. An area of inquiry important to the education, engagement and learning of students is their motivation or self-determination. Researchers commonly make an inference that motivation decreases as student's progress throughout their academic career, yet no empirical evidence has been gathered to support these claims. Therefore, the purpose of this study was to examine the self-determined motivation toward physical education of three different groups of students. Data …


Prescription Medicines: Decision-Making Preferences Of Patients Who Receive Different Levels Of Public Subsidy, Jane Robertson, Evan Doran, David A. Henry, Glenn P. Salkeld Jan 2014

Prescription Medicines: Decision-Making Preferences Of Patients Who Receive Different Levels Of Public Subsidy, Jane Robertson, Evan Doran, David A. Henry, Glenn P. Salkeld

Faculty of Social Sciences - Papers (Archive)

Objective  To compare the relative importance of medicine attributes and decision-making preferences of patients with higher or lower levels of insurance coverage in a publicly funded health care system. Design and setting  Cross-sectional telephone survey of randomly selected regular medicine users aged ≥18 years in the Hunter Valley, NSW, Australia. Main variables studied  Questions about 27 medicine attributes and active involvement in decisions to start a new medicine. Results  After adjustment, there were few differences between the 408 concession card holders (high insurance) and 410 general beneficiaries (low insurance) in their assessment of the importance of medicine attributes. For both …


What Is Good Parenting? The Perspectives Of Different Professionals, Philippa M. Eve, Mitchell K. Byrne, Cinzia R. Gagliardi, Jan 2014

What Is Good Parenting? The Perspectives Of Different Professionals, Philippa M. Eve, Mitchell K. Byrne, Cinzia R. Gagliardi,

Faculty of Social Sciences - Papers (Archive)

Defining parenting, and good parenting in particular, is a complex task wrought with ambiguities. This creates problems in agreeing on a standard parenting capacity assessment, particularly in relation to strengths as opposed to weaknesses. To address this lack of consensus, the current study explored the convergence and divergence of different professional groups' opinions on good parenting. A mixed-methods design was employed, with semi-structured interviews and rating scales administered to 19 professionals with experience in parenting capacity assessments. Data were analyzed using a constructivist grounded theory. The findings suggest that, in general, professionals agree on main themes of good parenting, including …


The Formation Of Complex Microstructures After Different Deformation Modes In Advanced High-Strength Steels, Ilana Timokhina, Elena V. Pereloma, Peter Hodgson Jan 2014

The Formation Of Complex Microstructures After Different Deformation Modes In Advanced High-Strength Steels, Ilana Timokhina, Elena V. Pereloma, Peter Hodgson

Faculty of Engineering and Information Sciences - Papers: Part A

The microstructure of transformation induced plasticity (TRIP) and dual phase (DP) multiphase steels after stamping of an industrial component at different strain levels was investigated using transmission electron microscopy. The TRIP steel microstructure showed a more complex dislocation substructure of ferrite at different strain levels than DP steel. The deformation microstructure of the stamped parts was compared to the deformation microstructure in these complex steels for different "equivalent" tensile strains. It was found that the microstructures are similar only at high levels of strain (>10 pct) for both steels.


Net Section Tension Capacity Of Equal Angle Braces Bolted At Different Legs, Lip H. Teh, Benoit Gilbert Jan 2014

Net Section Tension Capacity Of Equal Angle Braces Bolted At Different Legs, Lip H. Teh, Benoit Gilbert

Faculty of Engineering and Information Sciences - Papers: Part A

This paper points out that, in practice, the two connected ends of an angle brace or bracket may be bolted at different legs due to constructional constraints. However, no design equation for determining the net section tension capacity of such a connection exists, and neither do published laboratory test results. This paper presents a series of laboratory tensile test results involving equal angle braces bolted at different legs, with legs ranging from 50 to 75mm and tension distances ranging from 100 to 300mm. The specimens were composed of 3.0-mm G450 sheet steel, which is among those that have the lowest …


Behaviour Of Hollow Core Square Reinforced Concrete Columns Wrapped With Cfrp With Different Fibre Orientations, Muhammad N. Hadi, T D. Le Jan 2014

Behaviour Of Hollow Core Square Reinforced Concrete Columns Wrapped With Cfrp With Different Fibre Orientations, Muhammad N. Hadi, T D. Le

Faculty of Engineering and Information Sciences - Papers: Part A

Results of testing twelve hollow core square reinforced concrete columns wrapped with Carbon fibre 33 reinforced polymer (CFRP) are presented. The effect of fibre orientation on the performance of specimens 34 under concentric and eccentric loads was investigated. Twelve specimens were divided into four groups with three 36 specimens each. The specimens in the first reference group were unwrapped, while the specimens in the 37 remaining groups were wrapped with CFRP of different wrap combinations of three fibre orientations.The specimens in each group were tested 39 under three eccentricities: 0 (concentric), 25, and 50 mm up to failure. Test results …


Associations Between Body Mass Index And Musculoskeletal Pain And Related Symptoms In Different Body Regions Among Workers, Isabel Moreira-Silva, Rute Santos, Sandra Abreu, Jorge Mota Jan 2013

Associations Between Body Mass Index And Musculoskeletal Pain And Related Symptoms In Different Body Regions Among Workers, Isabel Moreira-Silva, Rute Santos, Sandra Abreu, Jorge Mota

Faculty of Social Sciences - Papers (Archive)

Obesity rates are high among employed adults and have shown a consistent increase over the past few decades. Musculoskeletal disorders related to work are a major cause of disability in working individuals. The objective of this study was to verify the associations between weight status and musculoskeletal pain and related symptoms in different body regions among workers. The sample comprised 203 factory workers. Anthropometric measures were assessed with standardized protocols and body mass index (BMI) was calculated. Participants were classified as nonoverweight (BMI ≤ 24.9 kg/m2) or overweight/obese (BMI ≥ 25 kg/m2). Musculoskeletal pain and related …


Germination And Dormancy Breaking: Two Different Things, Ken Thompson, Mark K. J Ooi Jan 2013

Germination And Dormancy Breaking: Two Different Things, Ken Thompson, Mark K. J Ooi

Faculty of Science, Medicine and Health - Papers: part A

RESPONSE to Finch-Savage and Footitt's opinion paper 'To germinate or not to germinate: a question of dormancy relief not germination stimulation'.


Timing Of Peak Blood Glucose After Breakfast Meals Of Different Glycemic Index In Women With Gestational Diabetes, Jimmy Chun Yu Louie, Tania P. Markovic, Glynis P. Ross, Deborah Foote, Jennie C. Brand-Miller Jan 2013

Timing Of Peak Blood Glucose After Breakfast Meals Of Different Glycemic Index In Women With Gestational Diabetes, Jimmy Chun Yu Louie, Tania P. Markovic, Glynis P. Ross, Deborah Foote, Jennie C. Brand-Miller

Faculty of Science, Medicine and Health - Papers: part A

This study aims to determine the peak timing of postprandial blood glucose level (PBGL) of two breakfasts with different glycemic index (GI) in gestational diabetes mellitus (GDM). Ten women with diet-controlled GDM who were between 30 and 32 weeks of gestation were enrolled in the study. They consumed two carbohydrate controlled, macronutrient matched bread-based breakfasts with different GI (low vs. high) on two separate occasions in a random order after an overnight fast. PBGLs were assessed using a portable blood analyser. Subjects were asked to indicate their satiety rating at each blood sample collection. Overall the consumption of a high …


Acute Effects Of Different Multivitamin Mineral Preparations With And Without Guaraná On Mood, Cognitive Performance And Functional Brain Activation, Andrew Scholey, Isabelle Bauer, Chris Neale, Karen Savage, David Camfield, David White, Silvia Maggini, Andrew Pipingas, Con Stough, Matthew Hughes Jan 2013

Acute Effects Of Different Multivitamin Mineral Preparations With And Without Guaraná On Mood, Cognitive Performance And Functional Brain Activation, Andrew Scholey, Isabelle Bauer, Chris Neale, Karen Savage, David Camfield, David White, Silvia Maggini, Andrew Pipingas, Con Stough, Matthew Hughes

Faculty of Social Sciences - Papers (Archive)

Previous work has identified the positive effects of the acute administration of a multivitamin-guaraná preparation during an effortful executive/working memory task. Here, we aimed to differentiate the effects of multivitamins with and without guaraná and to examine the neural substrates of such effects using functional magnetic resonance imaging (fMRI). Following a double-blind, placebo-controlled, randomised, balanced crossover design, 20 participants (mean age 29 ± 5.54 years) consumed multivitamin preparations with or without guaraná (Berocca® Performance and Boost, respectively) and a placebo. Thirty minutes post-treatment, they underwent neurocognitive assessment, consisting of a 10 min Cognitive Demand Battery, with mood ratings taken immediately …


Development Of An Instrument For Measuring Different Types Of Cognitive Load, J Leppink, Fred Paas, C Van Der Vleuten, Tamara Van Gog, Jeroen Van Merrienboer Jan 2013

Development Of An Instrument For Measuring Different Types Of Cognitive Load, J Leppink, Fred Paas, C Van Der Vleuten, Tamara Van Gog, Jeroen Van Merrienboer

Faculty of Social Sciences - Papers (Archive)

According to cognitive load theory, instructions can impose three types of cognitive load on the learner: intrinsic load, extraneous load, and germane load. Proper measurement of the different types of cognitive load can help us understand why the effectiveness and efficiency of learning environments may differ as a function of instructional formats and learner characteristics. In this article, we present a ten-item instrument for the measurement of the three types of cognitive load. Principal component analysis on data from a lecture in statistics for PhD students (n = 56) in psychology and health sciences revealed a three-component solution, consistent with …


What Is Different In Psychiatric Practice In Developing And Developed World? An Experiential Account From Australia And India, Nagesh Pai, Naveen Chandra Jan 2013

What Is Different In Psychiatric Practice In Developing And Developed World? An Experiential Account From Australia And India, Nagesh Pai, Naveen Chandra

Faculty of Science, Medicine and Health - Papers: part A

Abstract of a paper presented at the 65th Annual National Conference of Indian Psychiatric Society, Bangalor, 10-13 Jan, 2013. This is a narrative account of two psychiatrists (from Wollongong, NSW and Mangalore, India) who swapped their location or practice and reviewed their experiences.


Work Hardening Behaviors Of A Low Carbon Nb-Microalloyed Si-Mn Quenching-Partitioning Steel With Different Cooling Styles After Partitioning, Jun Zhang, Hua Ding, Chao Wang, Jingwei Zhao, Ting Ding Jan 2013

Work Hardening Behaviors Of A Low Carbon Nb-Microalloyed Si-Mn Quenching-Partitioning Steel With Different Cooling Styles After Partitioning, Jun Zhang, Hua Ding, Chao Wang, Jingwei Zhao, Ting Ding

Faculty of Engineering and Information Sciences - Papers: Part A

In this paper, the strain hardening behaviors of a low carbon Nb-microalloyed Si–Mn quenching–partitioning (Q–P) steel were investigated. The microstructures were analyzed by the scanning electron microscope (SEM) and transmission electron microscope (TEM). Mechanical tests were used to evaluate the room temperature tensile properties of the steel. The work hardening behaviors of the tested specimens were analyzed using the Hollomon approach. The results showed that a two-stage work hardening behavior was observed during deformation processes. In the first stage, for the quenched samples, martensite deforms plastically and the hardening exponent decreased. For the air-cooled samples, however, the carbide-free ferrite deforms …


Different Modes Of Dust Testing For Bulk Solids, Ian Frew, Peter W. Wypych, Leong Mar Jan 2013

Different Modes Of Dust Testing For Bulk Solids, Ian Frew, Peter W. Wypych, Leong Mar

Faculty of Engineering and Information Sciences - Papers: Part A

The loss of dust from the mining, processing, storage, handling, transportation and loading of bulk materials is creating an increasing number of problems for industry and the community. This includes loss of valuable material and export income, increasing workplace dust emissions (e.g. from mine sites, loading, receival, ports, bulk berths) and decreasing ambient air quality and human health, especially for nearby communities. It is virtually impossible to estimate the total cost of these problems to industry and the community. An initial key step in addressing dust problems is to quantify the dustiness or dustability of bulk materials. This paper examines …


The Small Heat-Shock Protein Αb-Crystallin Uses Different Mechanisms Of Chaperone Action To Prevent The Amorphous Versus Fibrillar Aggregation Of Α-Lactalbumin, Melissa Kulig, Heath Ecroyd Sep 2012

The Small Heat-Shock Protein Αb-Crystallin Uses Different Mechanisms Of Chaperone Action To Prevent The Amorphous Versus Fibrillar Aggregation Of Α-Lactalbumin, Melissa Kulig, Heath Ecroyd

Faculty of Science, Medicine and Health - Papers: part A

Stress conditions can destabilize proteins, promoting them to unfold and adopt intermediately folded states. Partially folded protein intermediates are unstable and prone to aggregation down off-folding pathways leading to the formation of either amorphous or amyloid fibril aggregates. The sHsp (small heat-shock protein) αB-crystallin acts as a molecular chaperone to prevent both amorphous and fibrillar protein aggregation; however, the precise molecular mechanisms behind its chaperone action are incompletely understood. To investigate whether the chaperone activity of αB-crystallin is dependent upon the form of aggregation (amorphous compared with fibrillar), bovine α-lactalbumin was developed as a model target protein that could be …


Influence Of Plantlet Age And Different Soilless Culture On Acclimatization Of Stemona Curtisii Hook.F., Jiraporn Palee, Srisulak Dheeranupattana, Araya Jatisatienr, Sunanta Wangkarn, Pitchaya Mungkornasawakul, Stephen Pyne, Alison Ung, Thanapat Sastraruji Jan 2012

Influence Of Plantlet Age And Different Soilless Culture On Acclimatization Of Stemona Curtisii Hook.F., Jiraporn Palee, Srisulak Dheeranupattana, Araya Jatisatienr, Sunanta Wangkarn, Pitchaya Mungkornasawakul, Stephen Pyne, Alison Ung, Thanapat Sastraruji

Faculty of Science, Medicine and Health - Papers: part A

The aim of this experiment was to study the optimal age of Stemona curtisii plantlets for acclimatization. The in vitro shoots of S. curtisii were cultured on Murashige and Skoog solid medium supplemented with 1 mg L-1 naphthalene acetic acid to induce roots. Then, the plantlets from in vitro culture of 4, 8 and 12 week-old were transferred into the soil and their survival rate during the acclimatization process in the greenhouse was investigated. It was found that the 8 week-old plantlets had the highest survival rate of 80%. However, to enhance the survival rate of these plantlets, a soilless …


It's Only Scary If It's About Me Or My Child: Different Responses To Emotional Appeals Targeting Asthma Awareness, Sandra C. Jones, Samantha L. Reis, Karen M. Larsen-Truong Jan 2012

It's Only Scary If It's About Me Or My Child: Different Responses To Emotional Appeals Targeting Asthma Awareness, Sandra C. Jones, Samantha L. Reis, Karen M. Larsen-Truong

Faculty of Social Sciences - Papers (Archive)

Abstract presented at Australian and New Zealand Marketing Academy Conference, Adelaide, 3-5 Dec 2012


Synthetic Populations: Review Of The Different Approaches, Johan Barthelemy, Eric Cornelis Jan 2012

Synthetic Populations: Review Of The Different Approaches, Johan Barthelemy, Eric Cornelis

Faculty of Engineering and Information Sciences - Papers: Part A

Microsimulations may involve a large number of agents. It is then practically impossible or too expensive to obtain a fully and complete disaggregated data set about these agents of interest. Moreover, if such a dataset was available, its use would be potentially problematic in view of stringent privacy laws. To address this problem one may build an articial population starting from known aggregate data. Most of the known generation methods are explained in this paper. Their advantages and limitations are discussed and references are given for further details.


Molecular Characterization Of Commensal Escherichia Coli Adapted To Different Compartments Of The Porcine Gastrointestinal Tract, Sam Abraham, David M. Gordon, James Chin, Huub J. M Brouwers, Peter Njuguna, Mitchell D. Groves, Ren Zhang, Toni A. Chapman Jan 2012

Molecular Characterization Of Commensal Escherichia Coli Adapted To Different Compartments Of The Porcine Gastrointestinal Tract, Sam Abraham, David M. Gordon, James Chin, Huub J. M Brouwers, Peter Njuguna, Mitchell D. Groves, Ren Zhang, Toni A. Chapman

Faculty of Science - Papers (Archive)

The role of Escherichia coli as a pathogen has been the focus of considerable study, while much less is known about it as a commensal and how it adapts to and colonizes different environmental niches within the mammalian gut. In this study, we characterize Escherichia coli organisms (n=146) isolated from different regions of the intestinal tracts of eight pigs (dueodenum, ileum, colon, and feces). The isolates were typed using the method of random amplified polymorphic DNA (RAPD) and screened for the presence of bacteriocin genes and plasmid replicon types. Molecular analysis of variance using the RAPD data showed that E. …


Different Radiolabelling Methods Alter The Pharmacokinetic And Biodistribution Properties Of Plasminogen Activator Inhibitor Type 2 (Pai-2) Forms, Marie Ranson, Paula Berghofer, Kara L. Vine, Ivan Greguric, Rachael Shepherd, Andrew Katsifis Jan 2012

Different Radiolabelling Methods Alter The Pharmacokinetic And Biodistribution Properties Of Plasminogen Activator Inhibitor Type 2 (Pai-2) Forms, Marie Ranson, Paula Berghofer, Kara L. Vine, Ivan Greguric, Rachael Shepherd, Andrew Katsifis

Faculty of Science - Papers (Archive)

Introduction: Tumour-associated urokinase plasminogen activator (uPA) is a critical marker of invasion and metastasis, and it is recognised as having strong prognostic relevance as well as being a therapeutic target. The specific uPA inhibitor plasminogen activator inhibitor type-2 (PAI-2, SerpinB2) specifically targets cell bound uPA and is internalised. Furthermore, preclinical studies have established the “proof-of-principle” of uPA-targeting by PAI-2-cytotoxin conjugates in human carcinoma models. However, these studies also suggest that PAI-2 is rapidly cleared via the renal system with low total dose reaching the tumour. In this study, a comparative single photon emission computed tomography (SPECT) and biodistribution (BD) analysis …


Different Methods For Ethical Analysis In Health Technology Assessment: An Empirical Study, Samuli Saarni, Annette J. Braunack-Mayer, Bjorn Hofmann, Gert-Jan Van Der Wilt Jan 2011

Different Methods For Ethical Analysis In Health Technology Assessment: An Empirical Study, Samuli Saarni, Annette J. Braunack-Mayer, Bjorn Hofmann, Gert-Jan Van Der Wilt

Faculty of Social Sciences - Papers (Archive)

Objectives: Ethical analysis can highlight important ethical issues related to implementing a technology, values inherent in the technology itself, and value-decisions underlying the health technology assessment (HTA) process. Ethical analysis is a well-acknowledged part of HTA, yet seldom included in practice. One reason for this is lack of knowledge about the properties and differences between the methods available. This study compares different methods for ethical analysis within HTA.

Methods: Ethical issues related to bariatric (obesity) surgery were independently evaluated using axiological, casuist, principlist, and EUnetHTA models for ethical analysis within HTA. The methods and results are presented and compared.

Results: …


Ability Of Different Measures Of Adiposity To Identify High Metabolic Risk In Adolescents, Carla Moreira, Rute Santos, Susana Vale, Paula Clara Santos, Sandra Abreu, Ana I. Marques, Luisa Soares-Miranda, Jorge Mota Jan 2011

Ability Of Different Measures Of Adiposity To Identify High Metabolic Risk In Adolescents, Carla Moreira, Rute Santos, Susana Vale, Paula Clara Santos, Sandra Abreu, Ana I. Marques, Luisa Soares-Miranda, Jorge Mota

Faculty of Social Sciences - Papers (Archive)

Introduction. This study aimed to evaluate the screening performance of different measures of adiposity: body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) for high metabolic risk in a sample of adolescents. Methods. A cross-sectional school-based study was conducted on 517 adolescents aged 15-18, from the Azorean Islands, Portugal. We measured fasting glucose, insulin, total cholesterol (TC), HDL-cholesterol, triglycerides, and systolic blood pressure. HOMA and TC/HDL-C ratio were calculated. For each of these variables, a Z-score was computed by age and sex. A metabolic risk score (MRS) was constructed by summing the Z-scores of all individual risk factors. …


Thermal Load And Physical Mobility Implications Of Body Armour Systems With Different Levels Of Protection, Daniel C. Billing, Jace R. Drain, Anne Van Den Heuvel, Gregory E. Peoples, Aaron J. Silk, Nigel A.S Taylor, Mark J. Patterson Jan 2010

Thermal Load And Physical Mobility Implications Of Body Armour Systems With Different Levels Of Protection, Daniel C. Billing, Jace R. Drain, Anne Van Den Heuvel, Gregory E. Peoples, Aaron J. Silk, Nigel A.S Taylor, Mark J. Patterson

Faculty of Health and Behavioural Sciences - Papers (Archive)

No abstract provided.