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Articles 61 - 90 of 122
Full-Text Articles in Social and Behavioral Sciences
Mass Spectrometric Investigation Of The Dna-Binding Properties Of An Anthracycline With Two Trisaccharide Chains, Celine Kelso, Vanessa Tillott, Juan Diego Rojas, Renata L. A Furlan, Gabriel Padilla, Jennifer L. Beck
Mass Spectrometric Investigation Of The Dna-Binding Properties Of An Anthracycline With Two Trisaccharide Chains, Celine Kelso, Vanessa Tillott, Juan Diego Rojas, Renata L. A Furlan, Gabriel Padilla, Jennifer L. Beck
Faculty of Science - Papers (Archive)
Cosmomycin D (CosD) is an anthracycline that has two trisaccharide chains linked to its ring system. Gel electrophoresis showed that CosD formed stable complexes with plasmid DNA under conditions where daunorubicin (Dn) and doxorubicin (Dx) dissociated to some extent during the experiments. The footprint and stability of CosD complexed with 10- and 16 mer DNA was investigated using several applications of electrospray ionisation mass spectrometry (ESI-MS). ESI-MS binding profiles showed that fewer CosD molecules bound to the sequences than Dn or Dx. In agreement with this, ESI-MS analysis of nuclease digestion products of the complexes showed that CosD protected the …
Integrated Late Quaternary Chronostratigraphy For San Salvador Island, Bahamas: Patterns And Trends Of Morphological Change In The Land Snail Cerion, Paul Hearty, Stephen A. Schellenberg
Integrated Late Quaternary Chronostratigraphy For San Salvador Island, Bahamas: Patterns And Trends Of Morphological Change In The Land Snail Cerion, Paul Hearty, Stephen A. Schellenberg
Faculty of Science - Papers (Archive)
Reconstructing the phylogeny and biogeography of the Caribbean land snail Cerion requires a robust stratigraphic and chronological framework. To this end, we have determined the stratigraphic succession on San Salvador, a Bahamian island with a rich fossil and modern Cerion fauna. A primary purpose of this paper is to independently verify this succession through whole-rock and Cerion aminostratigraphies and AMS 14C-based age models. Over 150 individual Cerion shells were age-ranked from 140 ka to modern using stratigraphic position and reverse-phase HPLC (RPC) amino acid racemization, which was sufficiently sensitive to resolve stratigraphic subunits within the Holocene and late Pleistocene. …
The Effect Of Exposure On Landscape Scale Soil Surface Temperatures And Species Distribution Models, Michael B. Ashcroft, Laurie Chisholm, Kris French
The Effect Of Exposure On Landscape Scale Soil Surface Temperatures And Species Distribution Models, Michael B. Ashcroft, Laurie Chisholm, Kris French
Faculty of Science - Papers (Archive)
Species distribution models (SDMs) often use elevation as a surrogate for temperature or utilise elevation sensitive interpolations from weather stations. These methods may be unsuitable at the landscape scale, especially where there are sparse weather stations, dramatic variations in exposure or low elevational ranges. The goal of this study was to determine whether radiation, moisture or a novel estimate of exposure could improve temperature estimates and SDMs for vegetation on the Illawarra Escarpment, near Sydney, Australia. Forty temperature sensors were placed on the soil surface of an approximately 12,000 ha study site between November 2004 and August 2006. Linear regression …
Human Pathogenic Streptococcal Proteomics And Vaccine Development, J. N. Cole, A. Henningham, C. M. Gillen, V. Ramachandran, Mark J. Walker
Human Pathogenic Streptococcal Proteomics And Vaccine Development, J. N. Cole, A. Henningham, C. M. Gillen, V. Ramachandran, Mark J. Walker
Faculty of Science - Papers (Archive)
Gram-positive streptococci are non-motile, chain-forming bacteria commonly found in the normal oral and bowel flora of warm-blooded animals. Over the past decade, a proteomic approach combining 2-DE and MS has been used to systematically map the cellular, surface-associated and secreted proteins of human pathogenic streptococcal species. The public availability of complete streptococcal genomic sequences and the amalgamation of proteomic, genomic and bioinformatic technologies have recently facilitated the identification of novel streptococcal vaccine candidate antigens and therapeutic agents. The objective of this review is to examine the constituents of the streptococcal cell wall and secreted proteome, the mechanisms of transport of …
Understanding The Tolerance Of Antarctic Mosses To Climate Change, Sharon A. Robinson, L J. Clarke
Understanding The Tolerance Of Antarctic Mosses To Climate Change, Sharon A. Robinson, L J. Clarke
Faculty of Science - Papers (Archive)
Climate change is expected to affect the high latitudes first and most severely, rendering Antarctica one of the most significant baseline environments for the study of global climate change. Despite this, there have been few long-term studies of the response of Antarctic vegetation to climate change. The Windmill Islands region supports some of the most extensive and best developed vegetation on continental Antarctica, with lush, green mossbeds along many of the lakes and melt streams close to Casey station. Over the past 12 years my University of Wollongong colleagues and I have studied the mosses of this region to better …
From Shell To Cell: Neutron Scattering Studies Of Biological Water Dynamics And Coupling To Activity, A. Frölich, F. Gabel, M. Jasnin, U. Lehnert, D. Oesterhelt, A. Stadler, M. Tehei, M. Weik, K. Wood, G. Zaccai
From Shell To Cell: Neutron Scattering Studies Of Biological Water Dynamics And Coupling To Activity, A. Frölich, F. Gabel, M. Jasnin, U. Lehnert, D. Oesterhelt, A. Stadler, M. Tehei, M. Weik, K. Wood, G. Zaccai
Faculty of Science - Papers (Archive)
An integrated picture of hydration shell dynamics and of its coupling to functional macromolecular motions is proposed from studies on a soluble protein, on a membrane protein in its natural lipid environment, and on the intracellular environment in bacteria and red blood cells. Water dynamics in multimolar salt solutions was also examined, in the context of the very slow water component previously discovered in the cytoplasm of extreme halophilic archaea. The data were obtained from neutron scattering by using deuterium labelling to focus on the dynamics of different parts of the complex systems examined.
The Holocene Paleo-Tsunami History Of West Australia, S. R. Scheffers, A. Scheffers, D. Kelletat, Edward A. Bryant
The Holocene Paleo-Tsunami History Of West Australia, S. R. Scheffers, A. Scheffers, D. Kelletat, Edward A. Bryant
Faculty of Science - Papers (Archive)
West Australian coastlines experienced several tsunamis in mid-Holocene times. To expand our knowledge about Holocene tsunami events in West Australia, the authors extended the previously studied spatial scale to include the central- and south-western coastlines. Several of the discovered events were mid- and young Holocene (≤1000 yr BP) tsunami impacts on the outer coast of the Cape Range Peninsula. Five hundred kilometres to the south between Cape Cuvier and Point Quobba, additional tsunami evidence exists on top of steep cliffs over a coastal stretch of 30 km. The sedimentary signature of two tsunamis is documented in this area by wide …
Antimalarial Activity Of 2,4-Diaminopyrimidines, J. Morgan, R. Haritakul, Paul A. Keller
Antimalarial Activity Of 2,4-Diaminopyrimidines, J. Morgan, R. Haritakul, Paul A. Keller
Faculty of Science - Papers (Archive)
A series of 2,4- and 4,6-diaminopyrimidines were prepared and evaluated for their in vitro antimalarial activity. Of the 12 compounds tested 7 showed reasonable activity with 1 having a sub-micromolar IC50.
Oxidative Coupling Of Indoles Using Thallium(Iii) Trifluoroacetate, Paul A. Keller, N. R. Yepuri, M. J. Kelso, M. Mariani, B. W. Skelton, A. H. White
Oxidative Coupling Of Indoles Using Thallium(Iii) Trifluoroacetate, Paul A. Keller, N. R. Yepuri, M. J. Kelso, M. Mariani, B. W. Skelton, A. H. White
Faculty of Science - Papers (Archive)
The oxidative coupling of polysubstituted electron-rich indoles mediated by thallium trifluoroacetate was found to be a facile, clean, and high yielding reaction. Indolic coupling sites were determined by the nature of the substituents present, with dimerisation at the indole 2-position being the dominant outcome. Indoles bearing two potential reaction sites with similar reactivity were additionally found to undergo heterocoupling.
An Intercomparison Of Ground-Based Solar Ftir Measurements Of Atmospheric Gases At Eureka, Canada, Clare Paton-Walsh, R. Mittermeier, W. Bell, H. Fast, N. B. Jones, A. Meier
An Intercomparison Of Ground-Based Solar Ftir Measurements Of Atmospheric Gases At Eureka, Canada, Clare Paton-Walsh, R. Mittermeier, W. Bell, H. Fast, N. B. Jones, A. Meier
Faculty of Science - Papers (Archive)
We report the results of an intercomparison of vertical column amounts of hydrogen chloride (HCl), hydrogen fluoride (HF), nitrous oxide (N2O), nitric acid (HNO3), methane (CH4), ozone (O3), carbon dioxide (CO2) and nitrogen (N2) derived from the spectra recorded by two ground-based Fourier transform infrared (FTIR) spectrometers operated side-by-side using the sun as a source. The procedure used to record spectra and derive vertical column amounts follows the format of previous instrument intercomparisons organised by the Network for Detection of Atmospheric Composition Change (NDACC), formerly known as the Network for Detection of Stratospheric Change (NDSC). For most gases the differences …
New Cyclic Peptides Via Ring-Closing Metathesis Reactions And Their Anti-Bacterial Activities, Timothy P. Boyle, John B. Bremner, Jonathan Coates, John Deadman, Paul A. Keller, Stephen G. Pyne, David I. Rhodes
New Cyclic Peptides Via Ring-Closing Metathesis Reactions And Their Anti-Bacterial Activities, Timothy P. Boyle, John B. Bremner, Jonathan Coates, John Deadman, Paul A. Keller, Stephen G. Pyne, David I. Rhodes
Faculty of Science - Papers (Archive)
As part of a program investigating cyclic peptides with an internal aromatic hydrophobic scaffold as potential novel anti-bacterial agents, we explored the synthesis of simple tyrosine-based systems. These were prepared via key intermediates containing internal allylglycine and allyltyrosine residues for subsequent ring closing metathesis reactions. Although the resulting anti-bacterial activity against Staphylococcus aureus was modest, this represents a novel and simple route to this class of compounds. One intermediate acyclic dipeptide precursor showed good activity against S. aureus with an MIC of 7.8 µg/mL.
Measurement Of Methanol Emissions From Australian Wildfires By Ground-Based Solar Fourier Transform Spectroscopy, Clare Paton-Walsh, Stephen R. Wilson, N. B. Jones, D. W. T. Griffith
Measurement Of Methanol Emissions From Australian Wildfires By Ground-Based Solar Fourier Transform Spectroscopy, Clare Paton-Walsh, Stephen R. Wilson, N. B. Jones, D. W. T. Griffith
Faculty of Science - Papers (Archive)
We report the first atmospheric column measurements of methanol made by ground-based solar Fourier transform infrared spectroscopy. The measurements were made through smoke plumes over South Eastern Australia during the Austral summers of 2001/2002 and 2002/2003. There is a strong correlation between the measured column amounts of methanol and simultaneous and co-located measurements of aerosol optical depth. An emission factor for methanol from Australian forest fires of 2.3 ± 0.8 grams per kilogram of dry fuel consumed is estimated by use of the correlations of methanol and carbon monoxide with aerosol optical depth and literature values for the emission factor …
Climate Change Impacts On Coastal Biodiversity, V R. Burkett, Robert J. Nicholls, Leandro Fernandez, Colin D. Woodroffe
Climate Change Impacts On Coastal Biodiversity, V R. Burkett, Robert J. Nicholls, Leandro Fernandez, Colin D. Woodroffe
Faculty of Science - Papers (Archive)
No abstract provided.
Foundational Myths: Country And Conservation In Australia, Michael Adams
Foundational Myths: Country And Conservation In Australia, Michael Adams
Faculty of Science - Papers (Archive)
In Australia, while each state has responsibility for the creation and management of their own national park systems, overall coordination is achieved through the Commonwealth National Reserve System. The Australian systems, like many others, are essentially based on the ‘Yellowstone model’ of protected areas: government owned and managed, precise boundaries, and with people present only as visitors or rangers (Stevens 1997). The Yellowstone model had its origins in wilderness protection, and despite many changes, wilderness persists as a foundational concept for Australian national parks.
Lions, Leopards And Muskoxen: A (Very) Light-Hearted Look At The Ups, Downs, Ins And Outs Of A Postdoctoral Career Through The Eyes Of Two Zoologists, Matt W. Hayward, Adam J. Munn
Lions, Leopards And Muskoxen: A (Very) Light-Hearted Look At The Ups, Downs, Ins And Outs Of A Postdoctoral Career Through The Eyes Of Two Zoologists, Matt W. Hayward, Adam J. Munn
Faculty of Science - Papers (Archive)
This paper arose out of a seminar series for the Royal Zoological Society of New South Wales' 2006 student forum and workshop, "From the Horse's Mouth: Career Insights from Working Zoologists".The paper is aimed mainly at horiours and postgraduate zoologists, and describes our experiences as postdoctoral researchers, including what postdoctoral research is, how we got to be there (a PhD is essential), whether it was what we hoped it would be (a resounding yes), a brief summary of some postdoctoral highlights (MWH researched lions in Africa and AM muskoxen in Alaska), and of course some lowlights (low income, short-term positions …
Contentious Issues In Human-Wildlife Encounters: Seeking Solutions Ina Changing Social Context, Daniel Lunney, Adam J. Munn, Will Meikle
Contentious Issues In Human-Wildlife Encounters: Seeking Solutions Ina Changing Social Context, Daniel Lunney, Adam J. Munn, Will Meikle
Faculty of Science - Papers (Archive)
No abstract provided.
Mechanistic Explanations For Juvenile Kangaroo Moralities: Broad Implications For The Population Dynamics Of Large Herbivores During Climate Change, Adam J. Munn, Terence J. Dawson
Mechanistic Explanations For Juvenile Kangaroo Moralities: Broad Implications For The Population Dynamics Of Large Herbivores During Climate Change, Adam J. Munn, Terence J. Dawson
Faculty of Science - Papers (Archive)
Why do juvenile kangaroos die during drought? Answering this question is important because juvenile mortality typically drives whole population dynamics of large herbivores. To clarify reasons for the vulnerability of juveniles we investigated the ecophysiology of young red kangaroos (Macropus rufus), Australia’s largest marsupial herbivore. Compared with adults, juveniles had higher energy and water needs; these were related to requirements for growth and thermoregulation. Most importantly, juveniles could not maintain growth on poorer quality (high-fibre) forage due to an inability to expand gut-fill. Adults could adjust gut-fill to compensate, thereby increasing their survivability in dry conditions when easily digestible, low-fibre …
Approaches To Development Of A User-Friendly Community Based Arsenic/Iron Removal Unit In Bangladesh, Khondoker Mahabub Hassan, Farooque Ahmed, Faisal Ibney Hai, Saleh Faraj Magram
Approaches To Development Of A User-Friendly Community Based Arsenic/Iron Removal Unit In Bangladesh, Khondoker Mahabub Hassan, Farooque Ahmed, Faisal Ibney Hai, Saleh Faraj Magram
Faculty of Science - Papers (Archive)
The present stydy focuses on the strategies to modify the design of a community based Arsenic - Iron Removal Unit (AIRU) based on the field performance of the AIRU and the feedback from the users. The ultimate aim was to offer a user-friendly and sustainable system. Appropriate modifications in the design of the developed unit reduced the propensities of water head-loss and media clogging, thereby yielding sustained flow rate. Introduction of a simple cleaning procerdure (98% flow-recovery with three successive backwashing sequences) successfully reduced the frequency of requirement of labor-intensive replacement of the whole filter media. Raw water with arsenic …
Soil Temperatures During Autumn Prescribed Burning: Implications For The Germination Of Fire Responsive Species?, Trent D. Penman, A L. Towerton
Soil Temperatures During Autumn Prescribed Burning: Implications For The Germination Of Fire Responsive Species?, Trent D. Penman, A L. Towerton
Faculty of Science - Papers (Archive)
Prescribed fire is a widely applied management tool in native forests. There have been concerns raised about the ecological impacts of prescribed fire on native flora. One aspect of the debate is the extent towhich prescribed fire heats the soil to levels reported to trigger germination in the soil seed banks.We used Thermochrons to test soil temperatures at 2 and 5 cm in prescribed burns in dry sclerophyll forests. Soil temperatures during the burns were generally low (<40◦C) with less than 5% of sites being exposed to temperatures necessary for the germination of fire-dependent shrub species. High temperatures were associated with high fuel consumption and large woody debris. This information suggests that prescribed fires, carried out according to standard practices, in these forests are unlikely to trigger germination in the majority of the soil-stored seed banks. If ecological burns in these forests are aimed at promoting populations of senescing obligate seeder species, they need to be hotter than standard practice if they are to achieve their objectives, although we acknowledge that there are inherent risks associated with hotter burns.
Applied Conservation Management Of A Threatened Forest Dependant Frog, Heleioporus Australiacus, Trent D. Penman, F Lemckert, M J Mahony
Applied Conservation Management Of A Threatened Forest Dependant Frog, Heleioporus Australiacus, Trent D. Penman, F Lemckert, M J Mahony
Faculty of Science - Papers (Archive)
Threatened species management should be based on reliable scientific research. The giant burrowing frog Heleioporus australiacus is a threatened species in south-eastern Australia, and is often recorded on land managed for commercial forestry. As a result, management prescriptions have been developed in the absence of significant research data. Here, we review the available research data and assess the potential for forest management practices to impact upon this species. The species is restricted to naturally vegetated areas, but avoids steep areas, large rivers and forests with high levels of vegetative ground cover. Individuals spend the majority of the year in the …
Germination Responses Of A Dry Sclerophyll Forest Soil-Stored Seedbank To Fire Related Cues, Trent D. Penman, D Binns, R Allen, R Shiels, S Plummer
Germination Responses Of A Dry Sclerophyll Forest Soil-Stored Seedbank To Fire Related Cues, Trent D. Penman, D Binns, R Allen, R Shiels, S Plummer
Faculty of Science - Papers (Archive)
Fire is an integral component of many ecosystems worldwide. Many plant species require fire-related cues, primarily heat and smoke, to trigger germination. Despite the importance of this process, the responses of many Australian species to these cues are unknown. Without this knowledge fire management strategies may be developed that are inappropriate for individual species and vegetation communities. In this study we examined the responses of a dry sclerophyll forest seed bank to heat and smoke germination cues. Analysis was possible for 48 taxa within the soil seedbank with 34 of these showing a response to one or both of the …
The Vegetation Requirements Of Superb Fairy-Wrens (Malurus Cyaneus) In Non-Urban Edge And Urbanised Habitats, H Parsons, Kristine O. French, R E. Major
The Vegetation Requirements Of Superb Fairy-Wrens (Malurus Cyaneus) In Non-Urban Edge And Urbanised Habitats, H Parsons, Kristine O. French, R E. Major
Faculty of Science - Papers (Archive)
Urbanisation has created an environment with a broad spectrum of habitats of differing quality for birds. Understanding habitat characteristics is necessary for effective conservation of species in urban environments. We investigated the vegetation requirements of a small, shrub-nesting, Australian bird, the Superb Fairy-wren (Malurus cyaneus), and the relative quality of urban habitats in the Illawarra region of New South Wales. Vegetation was assessed in three different habitats: suburban sites within Superb Fairy-wren territories (n = 20 sites), suburban sites where Fairy-wrens were absent (n = 20), and rural–woodland edge in which Fairy-wrens were present (n = 17). This third habitat …
Spatial Ecology Of The Giant Burrowing Frog (Heleioporus Australiacus): Implications For Conservation Prescriptions, Trent D. Penman, F Lemckert, M J Mahony
Spatial Ecology Of The Giant Burrowing Frog (Heleioporus Australiacus): Implications For Conservation Prescriptions, Trent D. Penman, F Lemckert, M J Mahony
Faculty of Science - Papers (Archive)
Management of threatened anurans requires an understanding of a species’ behaviour and habitat requirements in both the breeding and non-breeding environments. The giant burrowing frog (Heleioporus australiacus) is a threatened species in south-eastern Australia. Little is known about its habitat requirements, creating difficulties in developing management strategies for the species.Weradio-tracked 33 individual H. australiacus in order to determine their habitat use and behaviour. Data from 33 frogs followed for between 5 and 599 days show that individuals spend little time near (<15 m) their breeding sites (mean 4.7 days for males and 6.3 days for females annually). Most time is spent in distinct non-breeding activity areas 20–250m from the breeding sites. Activity areas of females were further from the breeding site (mean 143 m) than those of males (mean 99 m), but were not significantly different in size (overall mean 500m2; males 553m2; females 307m2). Within activity areas, each frog used 1–14 burrows repeatedly, which weterm home burrows. Existing prescriptions are inappropriate for this species and we propose protection of key populations in the landscape as a more appropriate means of protecting this species.
Dendrimer Hydrazides As Multivalent Transient Inter-Cellular Linkers, D Zhao, S-M Ong, Zhilian Yue, Z Jiang, Y-C Toh, M A. Khan, J Shi, C H Tan, J Chen, H Yu
Dendrimer Hydrazides As Multivalent Transient Inter-Cellular Linkers, D Zhao, S-M Ong, Zhilian Yue, Z Jiang, Y-C Toh, M A. Khan, J Shi, C H Tan, J Chen, H Yu
Faculty of Science - Papers (Archive)
Three-dimensional (3D) multi-cellular aggregates (MCAs), as a model scaffold-free tissue construct, are useful for engineering cell-dense and matrix-poor tissues for repair and regeneration applications. To facilitate rapid MCA formation with high degrees of linker consistency and performance, we synthesized a class of dendrimer hydrazides with 8, 16 and 32 arms that can react with the aldehyde on the modified cell surfaces to form MCAs. DAB-AM-16 hydrazide with 32 arms demonstrated the best cell aggregation ability as compared to the dendrimer hydrazides with fewer arms, facilitating MCA formation at lower linker concentrations, minimizing cytotoxicity. Characterization of the MCAs formed with 2 …
Malonate-Bound Structure Of The Glycerophosphodiesterase From Enterobacter Aerogenes (Gpdq) And Characterization Of The Native Fe2+ Metal-Ion Preference, Colin J. Jackson, Kieran S. Hadler, Paul D. Carr, Aaron J. Oakley, Sylvia Yip, Gerhard Schenk, David L. Ollis
Malonate-Bound Structure Of The Glycerophosphodiesterase From Enterobacter Aerogenes (Gpdq) And Characterization Of The Native Fe2+ Metal-Ion Preference, Colin J. Jackson, Kieran S. Hadler, Paul D. Carr, Aaron J. Oakley, Sylvia Yip, Gerhard Schenk, David L. Ollis
Faculty of Science - Papers (Archive)
The structure of a malonate-bound form of the glycerophosphodiesterase from Enterobacter aerogenes, GpdQ, has been refined at a resolution of 2.2 A ̊ to a final R factor of 17.1%. The structure was originally solved to 2.9 A ̊ resolution using SAD phases from Zn2+ metal ions introduced into the active site of the apoenzyme [Jackson et al. (2007), J. Mol. Biol. 367, 1047–1062]. However, the 2.9 A ̊ resolution was insufficient to discern significant details of the architecture of the binuclear metal centre that constitutes the active site. Furthermore, kinetic analysis revealed that the enzyme lost a significant amount …
Ti-In-Zircon Thermometry Applied To Contrasting Archean Metamorphic And Igneous Systems, Joe Hiess, Allen Phillip Nutman, Vickie C. Bennett, Peter Holden
Ti-In-Zircon Thermometry Applied To Contrasting Archean Metamorphic And Igneous Systems, Joe Hiess, Allen Phillip Nutman, Vickie C. Bennett, Peter Holden
Faculty of Science - Papers (Archive)
Ti-in-zircon thermometry with SHRIMP II multi-collector has been applied to two well-documented Archean igneous and metamorphic samples from southern West Greenland. Zircons from 2.71 Ga partial melt segregation G03/38 formed in a small (<1 >m(3)), closed system within a mafic rock under high pressure granulite facies conditions. Results of 14 Ti analyses present a mean apparent zircon crystallization temperature of 679 +/- 11 degrees C, underestimating independent garnet-clinopyroxene thermometry by 20-50 degrees C but consistent with reduced a(TiO2) in this system. 36 spot analysis on 15 zircons from 3.81 Ga meta-tonalite G97/18, with an estimated magmatic temperature >1000 degrees C, …
The Nagssugtoqidian Orogen In South-East Greenland: Evidence For Paleoproterozoic Collision And Plate Assembly, Allen Phillip Nutman, Feiko Kalsbeek, Clark R L Friend
The Nagssugtoqidian Orogen In South-East Greenland: Evidence For Paleoproterozoic Collision And Plate Assembly, Allen Phillip Nutman, Feiko Kalsbeek, Clark R L Friend
Faculty of Science - Papers (Archive)
The 200 km wide, east-west trending Paleoproterozoic mobile belt of the Ammassalik region of South-East Greenland contains a diverse assemblage of Paleoproterozoic and Archean rocks, variably affected by Paleoproterozoic deformations and high-grade low or high pressure metamorphism. By using previous field and geochemical data combined with new zircon dating and zircon trace element geochemistry, this mobile belt is confirmed as a 1870 to 1840 Ma collisional orogen, which contains one or more 1900 to 1880 Ma magmatic suites and northern and southern Archean basement terranes. The most studied 1900 to 1880 Ma magmatic suite is the Ammassalik Intrusive Complex, which …
Palaeoproterozoic And Archaean Gneiss Complexes In Northern Greenland: Palaeoproterozoic Terrane Assembly In The High Arctic, Allen Phillip Nutman, Peter Dawes, Feiko Kalsbeek, Mike Hamilton
Palaeoproterozoic And Archaean Gneiss Complexes In Northern Greenland: Palaeoproterozoic Terrane Assembly In The High Arctic, Allen Phillip Nutman, Peter Dawes, Feiko Kalsbeek, Mike Hamilton
Faculty of Science - Papers (Archive)
The Precambrian shield of northern Greenland has been investigated by SHRIMP U-Pb zircon dating of 14 orthogneisses and granitoids plus 5 metasediments, integrated with mapping by the Geological Survey of Denmark and Greenland and whole-rock Nd isotopic studies. The Inglefield Mobile Belt is a tract of Palaeoproterozoic sedimentation, plutonism, polyphase deformation and high-grade metamorphism that underlies Inglefield Land and northern Prudhoe Land. In the southern part of the belt at 78 degrees 30'N, the E-W-trending Sunrise Pynt Straight Belt is a high-grade, but structurally late, shear zone with contrasts in the geology on either side. South of the Sunrise Pynt …
High Resolution Analysis Of Uranium And Thorium Concentration As Well As U-Series Isotope Distributions In A Neanderthal Tooth From Payre (Ardeche, France) Using Laser Ablation Icp-Ms, R. Grun, Maxime Aubert, Renaud C. Joannes-Boyau, M-H Moncel
High Resolution Analysis Of Uranium And Thorium Concentration As Well As U-Series Isotope Distributions In A Neanderthal Tooth From Payre (Ardeche, France) Using Laser Ablation Icp-Ms, R. Grun, Maxime Aubert, Renaud C. Joannes-Boyau, M-H Moncel
Faculty of Science - Papers (Archive)
We have mapped U (238U) and Th (232Th) elemental concentrations as well as U-series isotope distributions in a Neanderthal tooth from the Middle Palaeolithic site of Payre using laser ablation ICP-MS. The U-concentrations in an enamel section varied between 1 and 1500 ppb. The U-concentration maps show that U-migration through the external enamel surface is minute, the bulk of the uranium having migrated internally via the dentine into the enamel. The uranium migration and uptake is critically dependent on the mineralogical structure of the enamel. Increased U-concentrations are observed along lineaments, some of which are associated with cracks, and others …
Unraveling The Mysteries Of Protein Folding And Misfolding, Heath Ecroyd, John A. Carver
Unraveling The Mysteries Of Protein Folding And Misfolding, Heath Ecroyd, John A. Carver
Faculty of Science - Papers (Archive)
This mini-review focuses on the processes and consequences of protein folding and misfolding. The latter process often leads to protein aggregation and precipitation with the aggregates adopting either highly ordered (amyloid fibril) or disordered (amorphous) forms. In particular, the amyloid fibril is discussed because this form has gained considerable notoriety due to its close links to a variety of debilitating diseases including Alzheimer's, Parkinson's, Huntington's, and Creutzfeldt-Jakob diseases, and type-II diabetes. In each of these diseases a different protein forms fibrils, yet the fibrils formed have a very similar structure. The mechanism by which fibrils form, fibril structure, and the …