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University of Wollongong

Faculty of Science - Papers (Archive)

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Full-Text Articles in Social and Behavioral Sciences

Molecular Characterization Of Commensal Escherichia Coli Adapted To Different Compartments Of The Porcine Gastrointestinal Tract, Sam Abraham, David M. Gordon, James Chin, Huub J. M Brouwers, Peter Njuguna, Mitchell D. Groves, Ren Zhang, Toni A. Chapman Jan 2012

Molecular Characterization Of Commensal Escherichia Coli Adapted To Different Compartments Of The Porcine Gastrointestinal Tract, Sam Abraham, David M. Gordon, James Chin, Huub J. M Brouwers, Peter Njuguna, Mitchell D. Groves, Ren Zhang, Toni A. Chapman

Faculty of Science - Papers (Archive)

The role of Escherichia coli as a pathogen has been the focus of considerable study, while much less is known about it as a commensal and how it adapts to and colonizes different environmental niches within the mammalian gut. In this study, we characterize Escherichia coli organisms (n=146) isolated from different regions of the intestinal tracts of eight pigs (dueodenum, ileum, colon, and feces). The isolates were typed using the method of random amplified polymorphic DNA (RAPD) and screened for the presence of bacteriocin genes and plasmid replicon types. Molecular analysis of variance using the RAPD data showed that E. …


Different Radiolabelling Methods Alter The Pharmacokinetic And Biodistribution Properties Of Plasminogen Activator Inhibitor Type 2 (Pai-2) Forms, Marie Ranson, Paula Berghofer, Kara L. Vine, Ivan Greguric, Rachael Shepherd, Andrew Katsifis Jan 2012

Different Radiolabelling Methods Alter The Pharmacokinetic And Biodistribution Properties Of Plasminogen Activator Inhibitor Type 2 (Pai-2) Forms, Marie Ranson, Paula Berghofer, Kara L. Vine, Ivan Greguric, Rachael Shepherd, Andrew Katsifis

Faculty of Science - Papers (Archive)

Introduction: Tumour-associated urokinase plasminogen activator (uPA) is a critical marker of invasion and metastasis, and it is recognised as having strong prognostic relevance as well as being a therapeutic target. The specific uPA inhibitor plasminogen activator inhibitor type-2 (PAI-2, SerpinB2) specifically targets cell bound uPA and is internalised. Furthermore, preclinical studies have established the “proof-of-principle” of uPA-targeting by PAI-2-cytotoxin conjugates in human carcinoma models. However, these studies also suggest that PAI-2 is rapidly cleared via the renal system with low total dose reaching the tumour. In this study, a comparative single photon emission computed tomography (SPECT) and biodistribution (BD) analysis …


Novel Technique Shows Different Hydrophobic Chemical Signatures Of Exotic And Indigenous Plant Soils With Similar Effects Of Extracts On Indigenous Species Seedling Growth, Emilie-Jane Ens, Kristine O. French, John B. Bremner, Jurgen Korth Jan 2010

Novel Technique Shows Different Hydrophobic Chemical Signatures Of Exotic And Indigenous Plant Soils With Similar Effects Of Extracts On Indigenous Species Seedling Growth, Emilie-Jane Ens, Kristine O. French, John B. Bremner, Jurgen Korth

Faculty of Science - Papers (Archive)

Changes to ecosystem abiotic parameters are regarded as possible mechanisms facilitating plant invasion and community composition shifts. This study compared the hydrophobic chemical signatures of soil from exotic bitou bush (Chrysanthemoides monilifera spp. rotundata) invaded, indigenous acacia (Acacia longifolia var. sophorae) dominated and bare sand (unvegetated) habitats using a novel, rapid, capturing technique which utilised AmberliteA (R) XAD4 resin filled bags that were placed in situ. The hydrophobic chemical signature of the bitou bush soil extract was significantly different to the acacia soil and bare sand extracts. High concentrations of 18 sesquiterpenes dominated the hydrophobic signature of the bitou bush …


Quasielastic And Elastic Scattering Studies Of Aligned Dmpc Multilayers At Different Hydrations, Marcus Trapp, Thomas Gutberlet, Fanni Juranyi, Moeava Tehei, Lambert Van Eijck, T Unruh, Judith Peters Jan 2010

Quasielastic And Elastic Scattering Studies Of Aligned Dmpc Multilayers At Different Hydrations, Marcus Trapp, Thomas Gutberlet, Fanni Juranyi, Moeava Tehei, Lambert Van Eijck, T Unruh, Judith Peters

Faculty of Science - Papers (Archive)

Lipid model membranes such as 1,2-Dimyristoyl-sn-Glycero-3-Phosphocholine (DMPC) serve as role models for their more complex counterparts in biological systems. Quasielastic neutron scattering (QENS) [1-3], inelastic neutron scattering (INS) [4] and neutron spin echo spectroscopy (NSE) [5] have been employed to study local as well as collective dynamics of these membranes on a ps-ns time scale. Most of these studies lack a systematic investigation of the behavior of the model membranes in dependence on their hydration. We now started a detailed investigation of hydration effect on model membrane systems. The complexity of the dynamics can be further reduced by selective deuteration, …


Impacts Of A Woody Invader Vary In Different Vegetation Communities, T J. Mason, K French Jan 2008

Impacts Of A Woody Invader Vary In Different Vegetation Communities, T J. Mason, K French

Faculty of Science - Papers (Archive)

The impact of an exotic species in natural systems may be dependent not only on invader attributes but also on characteristics of the invaded community. We examined impacts of the invader bitou bush, Chrysanthemoides monilifera ssp. rotundata , in fore and hind dune communities of coastal New South Wales, Australia. We compared invader impacts on vegetation structure, richness of both native and exotic growth forms and community variability in fore and hind dunes. We found that impacts of bitou invasion were context specific: in fore dune shrublands, functionally distinct graminoid, herb and climber rather than shrub growth forms had significantly …