Social and Behavioral Sciences Commons^™

Trends In Health Care Delivery Systems: Implications For Cancer Prevention And Control, Glen P. Mays

Health Management and Policy Presentations

The Affordable Care Act and larger economic forces are leading both health care providers and public health agencies to renegotiate their roles and responsibilities within the U.S. health system. This session reviews major changes occurring in both health care and public health delivery systems, with a focus on the implications for cancer prevention and control. The information infrastructure created by cancer registries and other health information systems are increasingly important for enabling greater coordination, alignment and accountability within the nation's changing delivery systems.

The National Health Security Preparedness Index: Proposed Updates For 2015-16, Glen P. Mays

Health Management and Policy Presentations

The U.S. Centers for Disease Control and Prevention (CDC) initiated development of the National Health Security Preparedness Index in 2012 to create a platform for measuring the nation’s progress in preparing for, responding to, and recovering from disasters and other large-scale emergencies that pose risks to health and well-being in the United States. As a measurement tool, the Index is designed to summarize levels of preparedness achieved within individual states and for the nation as a whole. This session summarizes proposed updates to the Index for 2015-16 that are designed to improve the validity and reliability of Index measures and …

Time-Dependent Effects Of Cx3cr1 In A Mouse Model Of Mild Traumatic Brain Injury, Heidi Y. Febinger, Hannah E. Thomasy, Maria N. Pavlova, Kristyn M. Ringgold, Paulien R. Barf, Amrita M. George, Jenna N. Grillo, Adam D. Bachstetter, Jenny A. Garcia, Astrid E. Cardona, Mark R. Opp, Carmelina Gemma

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Neuroinflammation is an important secondary mechanism that is a key mediator of the long-term consequences of neuronal injury that occur in traumatic brain injury (TBI). Microglia are highly plastic cells with dual roles in neuronal injury and recovery. Recent studies suggest that the chemokine fractalkine (CX3CL1, FKN) mediates neural/microglial interactions via its sole receptor CX3CR1. CX3CL1/CX3CR1 signaling modulates microglia activation, and depending upon the type and time of injury, either protects or exacerbates neurological diseases.

METHODS: In this study, mice deficient in CX3CR1 were subjected to mild controlled cortical impact injury (CCI), a model of TBI. We evaluated …

Albumin Administration In Acute Ischemic Stroke: Safety Analysis Of The Alias Part 2 Multicenter Trial, Michael D. Hill, Renee H. Martin, Yuko Y. Palesch, Claudias S. Moy, Diego Tamariz, Karla J. Ryckborst, Elizabeth B. Jones, David Weisman, L. Creed Pettigrew, Myron D. Ginsberg

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Albumin treatment of ischemic stroke was associated with cardiopulmonary adverse events in previous studies and a low incidence of intracranial hemorrhage. We sought to describe the neurological and cardiopulmonary adverse events in the ALIAS Part 2 Multicenter Trial.

METHODS: Ischemic stroke patients, aged 18-83 and a baseline NIHSS ≥ 6, were randomized to treatment with ALB or saline control within 5 hours of stroke onset. Neurological adverse events included symptomatic intracranial hemorrhage, hemicraniectomy, neurological deterioration and neurological death. Cardiopulmonary adverse events included pulmonary edema/congestive heart failure, acute coronary syndromes, atrial fibrillation, pneumonia and pulmonary thromboembolism.

RESULTS: …

Ebony And Ivory? Interracial Dating Intentions And Behaviors Of Disadvantaged African American Women In Kentucky, David J. Luke, Carrie B. Oser

Sociology Faculty Publications

Using data from 595 predominantly disadvantaged African American women in Kentucky, this study examines perceptions about racial/ethnic partner availability, cultural mistrust, and racism as correlates of interracial dating intentions and behaviors with both white and Hispanic men. Participants reported levels of dating intentions and behaviors were significantly higher with whites than Hispanics. The multivariate models indicate less cultural mistrust and believing it is easier to find a man of that racial/ethnic category were associated with higher interracial dating intentions. Women were more likely to have dated a white man if they believed it was easier to find a white man …

Temporary Assistance For Needy Families, James P. Ziliak

University of Kentucky Center for Poverty Research Discussion Paper Series

The provision of public assistance to families with children in America faced a watershed moment with the passage of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA). PRWORA replaced the Aid to Families with Dependent Children (AFDC) program, which was an entitlement funded via a federal-state matching grant, with Temporary Assistance for Needy Families (TANF), which is no longer an entitlement and is financed with a fixed federal block-grant to the states. The impetus for reform had been building for at least the two decades prior to passage, but took on greater currency with the dramatic growth …

Trouble In The Tails? What We Know About Earnings Nonresponse Thirty Years After Lillard, Smith, And Welch, Christopher R. Bollinger, Barry T. Hirsch, Charles M. Hokayem, James P. Ziliak

University of Kentucky Center for Poverty Research Discussion Paper Series

Earnings nonresponse in household surveys is widespread, yet there is limited evidence on whether and how nonresponse bias affects measured earnings. This paper examines the patterns and consequences of nonresponse using internal Current Population Survey individual records linked to administrative Social Security Administrative data on earnings for calendar years 2005-2010. Our findings confirm the conjecture by Lillard, Smith, and Welch (1986) that nonresponse across the earnings distribution is U-shaped. Left-tail “strugglers” and right-tail “stars” are least likely to report earnings. Household surveys understate earnings dispersion, reporting too few low and too few extremely high earners. Throughout much of the earnings …

Using Research And Roi To Drive Partnerships In Public Health Delivery Systems, Glen P. Mays

Health Management and Policy Presentations

Stimulating public-private partnerships (PPP) for health and economic development initiatives requires research that can answer key questions: (1) what are the health and economic returns likely to be realized; (2) over what time frames and with what certainty; (3) what investments are required to achieve results; and (4) what are the implementation strategies most likely to succeed. This presentation reviews ongoing research on the PPPs used to deliver public health services in the U.S., and explores the lessons this research offers PPPs in low and middle income countries. We examine how scientific evidence on public health delivery systems and their …

What It Takes To Get Passed On: Message Content, Style, And Structure As Predictors Of Retransmission In The Boston Marathon Bombing Response, Jeannette Sutton, C. Ben Gibson, Emma S. Spiro, Cedar League, Sean M. Fitzhugh, Carter T. Butts

Communication Faculty Publications

Message retransmission is a central aspect of information diffusion. In a disaster context, the passing on of official warning messages by members of the public also serves as a behavioral indicator of message salience, suggesting that particular messages are (or are not) perceived by the public to be both noteworthy and valuable enough to share with others. This study provides the first examination of terse message retransmission of official warning messages in response to a domestic terrorist attack, the Boston Marathon Bombing in 2013. Using messages posted from public officials' Twitter accounts that were active during the period of the …

Estimating Patient-Centered And Community-Centered Treatment Effects: Examples From Medical Care And Public Health, Glen P. Mays

Health Management and Policy Presentations

Health services researchers face growing clinical and policy imperatives for estimating how the effectiveness of medical and public health interventions vary across patients, population groups, and community settings. Recent advances in local instrumental variables estimation techniques allow for the estimation of person-specific and community-specific treatment effects in the presence of unobserved heterogeneity. This presentation explores examples from both medicine and public health following the local IV methods developed by Basu et al. (2013).

Preserving Kentucky’S Newspapers: Analogue Beginnings To Digital Frontier, Kopana Terry, Eric Weig

Library Presentations

Over fifty years ago an historian and a library director traveled the back roads of Kentucky (USA) with a portable microfilm camera, two lights, and a dream of preserving Kentucky’s newspapers. From their ambitions arose a successful newspaper preservation program at the University of Kentucky Libraries (UKL). Now in its sixth decade, the program has developed a new way of preserving contemporary born-digital newspapers. This paper explores some of the people and events behind the early success of UKL’s program, as well as an in-depth look at the development and functionality of Paper Vault: a largely automated, in-house process delivering …

Foundational Public Health Services And Health System Reform, Glen P. Mays

Health Management and Policy Presentations

The Institute of Medicine's 2012 report on public health financing recommended a national initiative to identify the components and costs of a "minimum package" of public health programs and infrastructure that should be available in every U.S. community. In response, efforts are now underway to reach consensus on a set of "Foundational Public Health Services" for the nation, and to identify resource requirements for implementing these services. This presentation reviews existing research on the current availability of Foundational Public Health Services across the U.S. and the health and economic effects attributable to these services. We also review progress on ongoing …

"Diversity + Inclusion = Community" Introduction And Wrap Up, Ruth E. Bryan

Library Presentations

This presentation articulates a definition of "diversity," "inclusion," and "community" as used by the Retreat Planning Committee to frame the speakers and activities at the University of Kentucky Libraries all-staff retreat in August 2015.

Fundamentals Of Economic Evaluation For Public Health, Glen P. Mays, Cezar Mamaril

Health Management and Policy Presentations

This workshop provides an overview of the design and implementation of economic evaluation studies of public health programs and policies. Strategies for integrating economic evaluation principles, measurement strategies, analytic approaches, and results into the routine operations of public health agencies are examined.

Developmental Changes In Analytic And Holistic Processes In Face Perception, Jane E. Joseph, Michelle D. Dibartolo, Ramesh S. Bhatt

Psychology Faculty Publications

Although infants demonstrate sensitivity to some kinds of perceptual information in faces, many face capacities continue to develop throughout childhood. One debate is the degree to which children perceive faces analytically versus holistically and how these processes undergo developmental change. In the present study, school-aged children and adults performed a perceptual matching task with upright and inverted face and house pairs that varied in similarity of featural or 2^nd order configural information. Holistic processing was operationalized as the degree of serial processing when discriminating faces and houses [i.e., increased reaction time (RT), as more features or spacing relations were …

Beyond Bivariate Correlations: Three-Block Partial Least Squares Illustrated With Vegetation, Soil, And Topography, Daehyun Kim, Thomas J. Dewitt, Cesar S. B. Costa, John A. Kupfer, Ryan W. Mcewan, J. Anthony Stallins

Geography Faculty Publications

Ecologists, particularly those engaged in biogeomorphic studies, often seek to connect data from three or more domains. Using three-block partial least squares regression, we present a procedure to quantify and define bi-variance and tri-variance of data blocks related to plant communities, their soil parameters, and topography. Bi-variance indicates the total amount of covariation between these three domains taken in pairs, whereas tri-variance refers to the common variance shared by all domains. We characterized relationships among three domains (plant communities, soil properties, topography) for a salt marsh, four coastal dunes, and two temperate forests spanning several regions in the world. We …

Your Professional Brand, Jennifer A. Bartlett

Library Faculty and Staff Publications

This column discusses recent publications in the library literature on the topic of professional marketing and promotion in the context of defining and establishing personal brands.

Student Loan Debt: The Devil Is In The Details, Christopher R. Bollinger

Issue Brief on Topics Affecting Kentucky’s Economy

Student loan debt has received a great deal of attention on in the popular press recently. However, the statistics and data that are frequently presented fail to fully capture the complexity of student loans and student debt. This brief presents a more complete picture of student loan debt, examining not only average debt of student borrowers, but presenting a full assessment of the distribution of debt and the types of schools.

Medicaid Crowd-Out Of Other Public Health Spending: Modeling Economic & Health Effects, Glen P. Mays

Health Management and Policy Presentations

MOTIVATION: Thirty states are expanding Medicaid eligibility under the Affordable Care Act (ACA) as of 2015, and while federal funds cover most costs for newly eligible recipients, states must share the additional costs of covering previously-eligible state residents who enroll in Medicaid. States, together with their local government counterparts, also provide the vast majority (87%) of public sector funds for public health programs designed to promote health and prevent disease and injury on a population-wide basis. Fiscal constraints and generous federal matching funds create strong budgetary incentives for states to channel their health-related spending to Medicaid rather than to other …

Altered Lysosomal Proteins In Neural-Derived Plasma Exosomes In Preclinical Alzheimer Disease, Edward J. Goetzl, Adam Boxer, Janice B. Schwartz, Erin L. Abner, Ronald C. Petersen, Bruce L. Miller, Dimitrios Kapogiannis

Sanders-Brown Center on Aging Faculty Publications

OBJECTIVE: Diverse autolysosomal proteins were quantified in neurally derived blood exosomes from patients with Alzheimer disease (AD) and controls to investigate disordered neuronal autophagy.

METHODS: Blood exosomes obtained once from patients with AD (n = 26) or frontotemporal dementia (n = 16), other patients with AD (n = 20) both when cognitively normal and 1 to 10 years later when diagnosed, and case controls were enriched for neural sources by anti-human L1CAM antibody immunoabsorption. Extracted exosomal proteins were quantified by ELISAs and normalized with the CD81 exosomal marker.

RESULTS: Mean exosomal levels of cathepsin D, lysosome-associated membrane …

Negative Urgency And Lack Of Perseverance: Identification Of Differential Pathways Of Onset And Maintenance Risk In The Longitudinal Prediction Of Nonsuicidal Self-Injury, Elizabeth N. Riley, Jessica L. Combs, Carol E. Jordan, Gregory T. Smith

Psychology Faculty Publications

Many researchers have identified impulsivity-related personality traits as correlates of and risk factors for nonsuicidal self-injury (NSSI). Using a longitudinal design, we tested the hypothesis that one such trait, negative urgency (the tendency to act rashly when distressed), predicts the onset of NSSI during the first year of college and a different trait, lack of perseverance (the disposition to fail to maintain focus on tasks that are difficult or boring), predicts the maintenance of NSSI during the first year of college. In a sample of n = 1,158 college women (mean age = 18.04, 95% of participants were 18 at …

The Streets As Examples Of “True” Democracy? The South-American Experience, Carlos De La Torre

Sociology Faculty Publications

Building on the existing literature this paper analyzes how – at the turn of the century and into the 21st century – activists in Ecuador, Venezuela and Bolivia constructed narratives that focused on “the people in action”. Advocates of the insurrections framed myths of the pure and oppressed people revolting against the tyranny of economic and political elites. Elites responded by differentiating the authentic people from the mob. Indigenous and other poor and non-white protestors were portrayed by elites as the rabble, as uncivilized, and in general, as a danger to democracy.

Southeastern Law Librarian Summer 2015, Seaall

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Low Neural Exosomal Levels Of Cellular Survival Factors In Alzheimer's Disease, Edward J. Goetzl, Adam Boxer, Janice B. Schwartz, Erin Abner, Ronald C. Petersen, Bruce L. Miller, Olga D. Carlson, Maja Mustapic, Dimitrios Kapogiannis

Sanders-Brown Center on Aging Faculty Publications

Transcription factors that mediate neuronal defenses against diverse stresses were quantified in plasma neural-derived exosomes of Alzheimer's disease or frontotemporal dementia patients and matched controls. Exosomal levels of low-density lipoprotein receptor-related protein 6, heat-shock factor-1, and repressor element 1-silencing transcription factor all were significantly lower in Alzheimer's disease patients than controls (P < 0.0001). In frontotemporal dementia, the only significant difference was higher levels of repressor element 1-silencing transcription factor than in controls. Exosomal transcription factors were diminished 2-10 years before clinical diagnosis of Alzheimer's disease. Low exosomal levels of survival proteins may explain decreased neuronal resistance to Alzheimer's disease neurotoxic proteins.

Characteristics Of A Megajournal: A Bibliometric Case Study, C. Sean Burns

Information Science Faculty Publications

The term megajournal is used to describe publication platforms, like PLOS ONE, that claim to incorporate peer review processes and web technologies that allow fast review and publishing. These platforms also publish without the constraints of periodic issues and instead publish daily. We conducted a yearlong bibliometric profile of a sample of articles published in the first several months after the launch of PeerJ, a peer reviewed, open access publishing platform in the medical and biological sciences. The profile included a study of author characteristics, peer review characteristics, usage and social metrics, and a citation analysis. We found …

Performance Assessment In Academic Libraries Through Campus Collaboration, Debbie Sharp, Beth Fuchs

Library Presentations

Librarians and classroom faculty share the common goal of developing students’ research abilities. This session will describe a collaborative approach to performance assessment of information literacy learning outcomes, one of our general education competencies. Through collaboration with faculty, we create an assessment that aligns course requirements with information literacy learning outcomes, and that can be applied across disciplines, departments, teaching formats, and class sizes. We will model the assessment process, and participants will use our rubric to score sample responses.

Undergraduate Diversity Scholar Program: A Proactive Approach To Creating An Inclusive And Multicultural Workforce, Adrian K. Ho, Judy Sackett

Library Presentations

The University of Kentucky (UK) Libraries approved a statement in September 2013 confirming its commitment to cultivating and encouraging diversity and inclusivity in its personnel policies and in its collections, programs, and services. The library subsequently developed an Undergraduate Diversity Scholar Program to provide two students with a paid internship in the 2014/15 academic year. UK undergraduates interested in diversity issues were encouraged to apply. Applicants were evaluated based on their work experience, volunteer or service activities, recommendations from two referees, and an essay about their belief in the benefits of a diverse society. The successful candidates started the inaugural …

Creating Effective Instructional Materials With I-Learn, Stacey Greenwell

Library Presentations

Given the proliferation of information and the lifelong importance of information literacy and critical thinking skills, librarians need to know how to best design information literacy instructional materials in order to help students locate, evaluate, and use information effectively. This poster builds upon an experimental research study conducted to determine how instructional materials designed using the I-LEARN model could increase student understanding and application of information literacy concepts. The findings from the research study show that I-LEARN can be particularly valuable in designing online course guides and provides an easy-to-use framework for developing reusable guide content.

Using Network Analysis To Understand Public Health Delivery Systems & Community Health Initiatives, Glen P. Mays

Health Management and Policy Presentations

The increasingly connected world of health care delivery relies on an expanding frontier of multi-stakeholder structures and processes, from interdisciplinary patient-centered care teams, to virtual accountable care organizations (ACOs), to complex community-level interventions. This session highlights recent advances in applying social network analysis (SNA) methods to study the implementation and impact of these types of innovations. This methods workshop examines the benefits and limits of novel SNA applications based on the expanding availability of large, linkable electronic clinical and administrative data sources with dependent data structures. This paper profiles examples of using SNA principles and methods to study the implementation …

Learning From Network Analysis: Care Transitions, Market Competition, & Community Interventions, Glen P. Mays

Health Management and Policy Presentations

The increasingly connected world of health care delivery relies on an expanding frontier of multi-stakeholder structures and processes, from interdisciplinary patient-centered care teams, to virtual accountable care organizations (ACOs), to complex community-level interventions. This methods workshop highlights recent advances in applying social network analysis (SNA) methods to study the implementation and impact of these types of innovations. This session will examine the benefits and limits of novel SNA applications based on the expanding availability of large, linkable electronic clinical and administrative data sources with dependent data structures.