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Social and Behavioral Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Psychology

Wayne State University

2018

Pain

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Full-Text Articles in Social and Behavioral Sciences

Pavlovian Conditioning: History And Application Of The Revaluation Procedure, Bana Odeh May 2018

Pavlovian Conditioning: History And Application Of The Revaluation Procedure, Bana Odeh

Honors College Theses

While Pavlovian conditioning is a widely recognized form of learning, the nature of this learned association continues to be debated and has significant implications for human and animal behavior. This paper will first address the basic structure of Pavlovian conditioning as well as the two major historical hypotheses—Stimulus-Stimulus (S-S) learning and Stimulus-Response (SR) learning—regarding the underlying neural representation of first-order conditioning. Next, the revaluation procedure, an experimental method used to distinguish between these two hypotheses, will be discussed. Furthermore, the history of revaluation studies on rats will be analyzed, with an emphasis on the specificity of the learned association formed, …


The Impact Of Neonatal Pain And Reduced Maternal Care On Brain And Behavioral Development, Sean Michael Mooney-Leber Jan 2018

The Impact Of Neonatal Pain And Reduced Maternal Care On Brain And Behavioral Development, Sean Michael Mooney-Leber

Wayne State University Dissertations

In the neonatal intensive care unit (NICU) preterm infants are exposed to a multitude of stressors, which include both neonatal pain and reduced maternal care. Clinical and preclinical research has demonstrated that exposure to neonatal pain and reduced maternal care has a profound negative impact on brain and behavioral development. Currently, the biological mechanism by which both of these stressors impacts brain and behavioral outcomes remains widely unknown. To uncover a potential biological mechanism, the current dissertation project utilized a preclinical model of repetitive needle pokes and developed a novel model of reduced maternal care through tea-ball encapsulation. Briefly, rat …