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Medicine and Health Sciences

Theses/Dissertations

2023

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Full-Text Articles in Social and Behavioral Sciences

Cultivating Health, Not Wealth In The United States' Healthcare System: Comprehensive Revisions For The Orphan Drug Act Of 1983, Kayla Smith Jan 2023

Cultivating Health, Not Wealth In The United States' Healthcare System: Comprehensive Revisions For The Orphan Drug Act Of 1983, Kayla Smith

Regis University Student Publications (comprehensive collection)

This thesis explores the way in which the Orphan Drug Act of 1983, originally instituted in response to a lack of treatments for rare diseases in the United States of America, has failed to achieve its initial objectives in the 40 years since its implementation. In evaluating various successful examples of government subsidization programs designed to intervene in private industry, this thesis composes the criterion required for funding-based legislation which maximize market outcomes while minimizing tax-payer burden. An analysis of the synthetic organic chemistry industry – and a case study into the production of a particular orphan treatment for a …


Complex Narratives Of Individuals Living With Alpha-Gal Syndrome (Ags). A Mixed-Methods Investigation: Examined Through Self-Reported Data, In-Person Interviews, And A Group Body Mapping Art Therapy Intervention, Sylvan Streightiff Jan 2023

Complex Narratives Of Individuals Living With Alpha-Gal Syndrome (Ags). A Mixed-Methods Investigation: Examined Through Self-Reported Data, In-Person Interviews, And A Group Body Mapping Art Therapy Intervention, Sylvan Streightiff

Art Therapy | Master's Theses

Alpha-gal (galactose-α-1,3-galactose) Syndrome or AGS is an under-recognized chronic condition which coincides with tick-bite exposure, resulting in a unique allergy to non-primate mammalian products and byproducts (in addition to other items caring the α-gal epitope such as carrageenan, agar-agar, and nori). This paper explores the experiences of individuals with this illness, establishing psychological context for expressed symptomatology, while emphasizing the complex trauma rooted in the population’s experiences of the life-altering and life-threatening contexts associated with managing AGS. This research is structured with Acceptance and Commitment Therapy (ACT) theory and utilizes a mixed-methods approach to arts-based research with the goal of …


Family-Based Support As Social Determinants Of Health Protective Factor On Depression Of Parents Of Children With Autism Spectrum Disorder, Bisola E. Duyile Jan 2023

Family-Based Support As Social Determinants Of Health Protective Factor On Depression Of Parents Of Children With Autism Spectrum Disorder, Bisola E. Duyile

Theses and Dissertations

All parents experience challenges in their caregiving roles (Barańczuk & Pisula, 2020). However, parents raising a child/children with disabilities experience different social barriers (Oliver, 1996) that may also contribute to additional stressors in their caregiving role (Tomeny, 2016). Although these parents, on average, have reported greater symptoms of depression than parents of typically developing children, research shows that parents who reported receiving social support had lower symptoms of depression and stress (Das et al., 2017; Singh et al., 2017). Through the social determinants of health (SDOH) framework (ODPHP, 2022), the present study investigated informal/family-based support and its protective impact on …


Addressing Death Distress In Caregivers Of Patients With Malignant Glioma, Kelcie D. Willis Jan 2023

Addressing Death Distress In Caregivers Of Patients With Malignant Glioma, Kelcie D. Willis

Theses and Dissertations

The field of psychosocial oncology seeks to improve the quality of life of patients and families affected by cancer. This task becomes increasingly important when there are limited, non-curative treatment options, a high probability of recurrence, and rapid functional decline, such as in the case of a malignant glioma (MG). Indeed, the diagnosis of a MG is associated with negative sequalae that often translates to higher caregiver burden. Caregivers—who must manage the functional decline of the patient, changes within the family, and a complicated medical system—often feel overwhelmed, isolated, and ill-equipped to handle these myriad responsibilities. While they also report …


The Impact Of A Parent-Only Pediatric Obesity Intervention Program On Quality Of Life In Racially Diverse Children, Taylor Vashro Jan 2023

The Impact Of A Parent-Only Pediatric Obesity Intervention Program On Quality Of Life In Racially Diverse Children, Taylor Vashro

Theses and Dissertations

Pediatric obesity has been associated with significant decrements in pediatric quality of life (QOL) comparable with severe pediatric diseases such as cancer. Parenting interventions have yielded health benefits for children with obesity; however, few studies have investigated the impact of parent-focused interventions on QOL in children with overweight and obesity. This study investigated the impact of a 6-week intensive parenting intervention program on the QOL of 5-12 year old, predominantly Black children with overweight and obesity. Parents were randomized into either the parenting intervention (NOURISH+) or a control group, and QOL, as well as variables related to child and parenting …


Assessing The Relationships Between Direct And Vicarious Exposure To Healthcare Discrimination And Erasure, Mistrust In Healthcare, And The Healthcare Utilization Behaviors Among Transgender And Gender Independent Individuals, Kyle L. Mason Jan 2023

Assessing The Relationships Between Direct And Vicarious Exposure To Healthcare Discrimination And Erasure, Mistrust In Healthcare, And The Healthcare Utilization Behaviors Among Transgender And Gender Independent Individuals, Kyle L. Mason

Theses and Dissertations

Healthcare inaccessibility through direct exposure (i.e., personal) to myriad forms of gender identity-related discrimination and erasure among the Transgender and Gender Independent (TGI) population has been documented by prior studies. The myriad barriers that individuals who embody TGI identities encounter to accessing healthcare are associated with the underutilization of healthcare, which may further exacerbate the health disparities that exist between this population and cisgender individuals in the United States (U.S.). Although the impacts of the harm that direct exposure to healthcare discrimination and erasure may have on TGI individuals are known, their exposure to such harm vicariously (i.e., through observation …


Provider Racial Concordance And Medical Mistrust In Pediatric Dentistry, Chinelo Eke Jan 2023

Provider Racial Concordance And Medical Mistrust In Pediatric Dentistry, Chinelo Eke

Theses and Dissertations

Purpose: Studies have drawn varying conclusions on the importance of a racially concordant patient provider relationship. Medical mistrust has continued to garner attention as healthcare enterprises thread equity, diversity and inclusion throughout their organizational policies, practices and systems.

Methods: Parents/caregivers of pediatric patients at VCU Pediatric Dentistry were invited to participate. Surveys included questions about demographics, racial concordance, language preference, and the validated Group-Based Medical Mistrust Scale.

Results: A total of 246 guardians completed the survey. For guardians, 40% reported Black or African American, 31% Hispanic, and 19% Caucasian. Seventy-one percent of guardians reported speaking English, 18% Spanish, and 11% …


Prenatal Ethanol Exposure Impairs Performance On Spatial And Tactile Sequential Discrimination Task In Juvenile Rats, Caleb S. Bailey Jan 2023

Prenatal Ethanol Exposure Impairs Performance On Spatial And Tactile Sequential Discrimination Task In Juvenile Rats, Caleb S. Bailey

Theses and Dissertations--Psychology

Fetal alcohol spectrum disorders (FASDs) are a set of cognitive and behavioral abnormalities that arise in ~5% of children who have been prenatally-exposed to alcohol. Prenatal alcohol exposure (PAE) can cause impairments in learning acquisition, working memory, response inhibition, and attentional-set shifting that result in exaggerated deficits in executive function and impairments in goal-seeking behavior. There are standard procedures used in rodent research to address some components of these deficits, but few procedures are sensitive enough to comprehensively assess such deficits. To address this issue in FASDs research techniques, we developed a procedure that requires prolonged executive function in a …


An Evaluation Of A Health, Wellbeing And Lifestyle Promotion Intervention Among A Cohort Of Year 1 Male Gaelic Games Student Athletes In An Irish University Setting, Anthony Casey Jan 2023

An Evaluation Of A Health, Wellbeing And Lifestyle Promotion Intervention Among A Cohort Of Year 1 Male Gaelic Games Student Athletes In An Irish University Setting, Anthony Casey

Theses

Background: The current research investigated the health, wellbeing and lifestyle behaviours of a cohort of 1st year male Gaelic Games student athletes (Study 1), and subsequently evaluated the impact of a bespoke intervention on these health, wellbeing and lifestyle behaviours in the same cohort (Study 2).

Methods: Participants were 1st year male Gaelic Games student athletes (mean age 18.6 ± 0.6 years, n=166) in a university in southern Ireland. Data were collected using a mixed-methods approach during the 2018/19 and the 2019/20 academic years. Data collection consisted of an online questionnaire (Bickerdike et al., 2018), which assessed health, wellbeing …


Effects Of Social Isolation And Adolescent Ethanol Exposure On Adult Drinking And Nicotine Co-Use, Jakob Shaykin Jan 2023

Effects Of Social Isolation And Adolescent Ethanol Exposure On Adult Drinking And Nicotine Co-Use, Jakob Shaykin

Theses and Dissertations--Psychology

Alcohol use often begins in adolescence and can lead to increased susceptibility to AUD in adulthood. Stress in the form of social isolation during adolescence can also prompt substance use disorders later in adulthood. This thesis determined if exposure to ethanol (EtOH) during adolescence and social isolation alters the trajectory of alcohol and nicotine intake during adulthood. In Experiment 1, adolescent male and female Sprague-Dawley rats were administered intermittent injections of EtOH (2g/kg 20% EtOH, IP) or saline (PND 28-41). EtOH consumption was measured in adulthood (PND 49-55) using a 2-bottle choice procedure where one bottle contained a 0.2% saccharin/15% …


The Effects Of Extended Fructose Access On Relative Value And Demand For Fructose, Saccharin, And Ventral Tegmental Stimulation, Megan Halloran Jan 2023

The Effects Of Extended Fructose Access On Relative Value And Demand For Fructose, Saccharin, And Ventral Tegmental Stimulation, Megan Halloran

Theses and Dissertations--Psychology

Globally, food addiction (FA) is a growing area of research and is largely attributed to the availability of foods that are both energy dense and high in fats and sugars. Further, it has been suggested, that sugar and fat, when consumed frequently, have properties similar to drugs of abuse. While the validity of FA is questioned, researchers have drawn parallels between substance use disorder (SUD) and FA. For example, sugar binge models emphasize craving, withdrawal and binging as primary components of FA, which are also hallmarks of SUD. Additionally, both natural rewards, like sugars, and drug rewards act on the …


Calcium Imaging Of Central Amygdala Activity After Fentanyl Escalation, Samantha Malone Jan 2023

Calcium Imaging Of Central Amygdala Activity After Fentanyl Escalation, Samantha Malone

Theses and Dissertations--Psychology

Evidence suggests that rats given long access (LgA) sessions to self-administer (SA) opioids escalate their intake, while also showing greater withdrawal severity and drug-induced reinstatement compared to rats maintained on short access (ShA) daily SA sessions. Little is known about the neural changes that occur during opioid escalation that may impact withdrawal and relapse. Past work examining opioid SA using ShA sessions in rodents has identified the central amygdala (CeA) as an area of interest that becomes hyperactive in acute withdrawal and may be involved in the incubation of craving that occurs after protracted withdrawal. However, these studies have not …


Still, We Thrive: Understanding How Gay, Bisexual, Transgender, And Other Men Who Have Sex With Men (Gbtmsm) Experience Structural Barriers & Facilitators To Wellness, Lucas Gergyek Jan 2023

Still, We Thrive: Understanding How Gay, Bisexual, Transgender, And Other Men Who Have Sex With Men (Gbtmsm) Experience Structural Barriers & Facilitators To Wellness, Lucas Gergyek

Theses and Dissertations (Comprehensive)

Historically and concurrently, structural violence has been a significant force influencing the sexual health and broader health of gay, bisexual, transgender and other men who have sex with men (GBTMSM). Yet to date, the majority of projects exploring the health inequities facing GBTMSM have focused on intrapsychic and behavioural factors as most related to poor health outcomes. As well, these studies are sometimes deficits focused, and fail to evaluate how GBTMSM continue to thrive, and maintain positive health. As a result, the ways in which systems and policies underlie and perpetuate health inequities facing GBTMSM have been somewhat obscured. Connectedly, …


Ethical Dilemmas And Moral Distress In Companion Animal Veterinary Medicine: Mental Health Implications, Bronwyn Dickson Jan 2023

Ethical Dilemmas And Moral Distress In Companion Animal Veterinary Medicine: Mental Health Implications, Bronwyn Dickson

Theses and Dissertations (Comprehensive)

Mental health concerns are a significant problem in the veterinary community, and studies suggest that veterinarians working in Western countries are at higher risk of suicide compared to the general population and other healthcare professionals (Bartram et al., 2009; Bartram & Baldwin, 2010; Platt et al., 2012). Additionally, veterinary medicine is an occupation inundated with complex ethical and moral dilemmas. However, current studies are limited in their ability to contextualize the risk and contributing factors fully; therefore, they offer limited insight into effective preventative and support strategies. Using Interpretive Phenomenological Analysis (IPA), eight companion animal veterinarians were interviewed about their …


The Impact Of Weighted Football Training On The Skill Acquisition Processes Of Place-Kicking In Sport, Sam Jermyn Jan 2023

The Impact Of Weighted Football Training On The Skill Acquisition Processes Of Place-Kicking In Sport, Sam Jermyn

Theses

Weighted implement training (WIT) involves performance of sport-specific motor skills with heavier-than-normal sporting implements. Typically, full range of motion (ROM) and similar kinematic characteristics of the respective motor skill are maintained concurrent to minimal changes in the force-velocity movement profile. While the majority of WIT research has been conducted in baseball, track and field, and cricket, there is a paucity of research conducted in the football codes, particularly Gaelic football. Existing observations of increased standard implement velocity and distance following the use of weighted implements infers potential benefits for Gaelic football performance, such as increasing kick-out ball velocity (BV) and …


‘A Healthy Mtu’ A Mixed Methods Baseline Programme Of Research To Empirically Inform A Campus Health Promotion Initiative Within An Irish Higher Education Setting, Andrea Bickerdike Jan 2023

‘A Healthy Mtu’ A Mixed Methods Baseline Programme Of Research To Empirically Inform A Campus Health Promotion Initiative Within An Irish Higher Education Setting, Andrea Bickerdike

Theses

Higher Education Institutions (HEIs) have been called to lead global health promotion actions, yet there remains a dearth of empirically informed ‘Healthy University’ (HU) initiatives. This thesis constituted a baseline mixed methods needs assessment to inform a settings-based health promotion (HP) initiative (‘A Healthy MTU’) within a multi-campus ‘case’ HEI in Ireland (Cork campuses of MTU, formerly CIT). Specific aims were to (i) investigate student and staff health metrics, and (ii) identify the cultural and environmental determinants of health and wellbeing within the case HEI setting. Using a phased, mixed methodology (QUAN-QUAL), five sequential empirical studies were undertaken. Quantitative data …


Medical Providers' Use Of Maternal Mental Health Screening Tools During Prenatal Appointments In Southeast Georgia, Andreka Ewing Jan 2023

Medical Providers' Use Of Maternal Mental Health Screening Tools During Prenatal Appointments In Southeast Georgia, Andreka Ewing

Electronic Theses and Dissertations

In the United States, maternal mental health disorders are the most common comorbidities experienced during pregnancy and after childbirth. In particular, the state of Georgia reports that 1 in 7 Georgian mothers experience depression, anxiety, obsessive-compulsive disorders, or psychosis related to these disorders. Research suggests that untreated maternal mental health can have adverse effects on the mother and unborn child. Conditions such as autism, mixed handedness, reduced cognitive ability, and affective disorders can develop while the child is in the womb of a depressed mother. Routine maternal mental health screening using a validated screening tool has been recommended to help …


The Digital Divide: The Path Towards Digital Inclusivity, Angelica Gonzalez Almanza Jan 2023

The Digital Divide: The Path Towards Digital Inclusivity, Angelica Gonzalez Almanza

Social Justice | Senior Theses

The gap between those Americans who use or have access to ICTs and those who do not is referred to as the digital divide (PACEs, 2002). The pandemic has increased dependence on technology and exacerbated the digital divide, which perpetuates existing systems of racism and poverty (Early et al., 2021). In this study, a mixed-method approach was conducted to understand what digital literacy skills parents need to overcome the digital divide and support their child's education. Specifically, the study explored how the program Impact Technology training has affected parents' involvement with their child's education. There were 175 Latinx parents that …


Understanding Language Barriers And Its Implications On Patient Outcomes In The Urgent Care Situation, Nicolo Co Jan 2023

Understanding Language Barriers And Its Implications On Patient Outcomes In The Urgent Care Situation, Nicolo Co

Nursing | Senior Theses

Background

A common goal for healthcare is healthcare for all, through which can be achieved when communication between the client and healthcare team is established. There are millions of immigrants worldwide who are not granted the healthcare that they deserve simply because of a lack of understanding in a country’s dominant language.

Patients with a limited language proficiency in a new country can have difficulty in understanding the care that they receive, which leads them to toil with understanding their healthcare options, let alone establishing expectations. This issue also stretches onto the risks of patient safety, in which urgent needs …


A Literature Review Evalating Ptsd Rates Among Healthcare Professionals Working In Emergency Transport And Critical Care Settings, Keenan Mai Jan 2023

A Literature Review Evalating Ptsd Rates Among Healthcare Professionals Working In Emergency Transport And Critical Care Settings, Keenan Mai

Nursing | Senior Theses

Background: The occupational stressors experienced by nurses and assistive personnel working in critical care settings can be extremely detrimental to their overall mental health. Employees in specialized units such as the Intensive Care Unit (ICU), cardiac intensive care unit (CICU), surgical trauma intensive care unit (STICU), pediatric intensive care unit (PICU), medical intensive care unit (MICU), neonatal intensive care unit (NICU), Emergency Department (ED) or Emergency Room (ER), and Critical Care Transport (CCT) settings are responsible for patients requiring a higher level of care, and consequently, have more to worry about throughout their workday. Research Question: Climbing rates of Post-Traumatic …


The Effects Of School-Based Art Therapy On Depressed Adolescents, Jasmine Nicolas Jan 2023

The Effects Of School-Based Art Therapy On Depressed Adolescents, Jasmine Nicolas

Nursing | Senior Theses

Depression in adolescents is associated with deficient behavioral and health outcomes (Fletcher, 2019). Art therapy has been shown to be effective in treating mental health condition such as depression. A student’s academic success heavily depends on treating their depression. Community health nurses can play a vital role in advocating for adequate mental health support to improve a student’s overall well-being and academic success. The literature review contains six articles on the prevalence and impact of depression among adolescents, art therapy as an intervention for improving psychological outcomes and resilience among adolescents, and experiences of adolescent clients in art therapy within …