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Full-Text Articles in Statistics and Probability

Tests For 2 X 2 Tables In Clinical Trials, Vic Hasselblad, Yulia Lokhnygina Nov 2007

Tests For 2 X 2 Tables In Clinical Trials, Vic Hasselblad, Yulia Lokhnygina

Journal of Modern Applied Statistical Methods

Five standard tests are compared: chi-squared, Fisher's exact, Yates’ correction, Fisher’s exact mid-p, and Barnard’s. Yates’ is always inferior to Fisher’s exact. Fisher’s exact is so conservative that one should look for alternatives. For certain sample sizes, Fisher’s mid-p or Barnard’s test maintain the nominal alpha and have superior power.


Sample Size Determination In Animal Health Studies, Zhanglin Cui, Alan G. Zimmermann, Daniel H. Mowrey Apr 2007

Sample Size Determination In Animal Health Studies, Zhanglin Cui, Alan G. Zimmermann, Daniel H. Mowrey

Conference on Applied Statistics in Agriculture

Oftentimes in animal health studies, a treatment group is randomly assigned to a pen of animals, and the pen of animals as a whole is treated (fed the same medicated feed or water) together. In this scenario, the pen of animals is the experimental unit and the individual animal may be an observational unit. In addition to having the pen as the experimental unit, if multiple sites are used and site is treated as a random factor, this adds complexity to the study. To properly design the study, it is necessary to determine the number of animals in a pen, …