Statistics and Probability Commons^™

Data Combination From Multiple Sources Under Measurement Error, Hugo Gasca-Aragon

Open Access Dissertations

Regulatory Agencies are responsible for monitoring the performance of particular measurement communities. In order to achieve their objectives, they sponsor Intercomparison exercises between the members of these communities. The Intercomparison Exercise Program for Organic Contaminants in the Marine Environment is an ongoing NIST/NOAA program. It was started in 1986 and there have been 19 studies to date. Using this data as a motivation we review the theory and practices applied to its analysis.

It is a common practice to apply some kind of filter to the comparison study data. These filters go from outliers detection and exclusion to exclusion of …

In Silico Surveillance: Evaluating Outbreak Detection With Simulation Models, Bryan Lewis, Stephen Eubank, Allyson M. Abrams, Ken Kleinman

Public Health Department Faculty Publication Series

Background

Detecting outbreaks is a crucial task for public health officials, yet gaps remain in the systematic evaluation of outbreak detection protocols. The authors’ objectives were to design, implement, and test a flexible methodology for generating detailed synthetic surveillance data that provides realistic geographical and temporal clustering of cases and use to evaluate outbreak detection protocols.

Methods

A detailed representation of the Boston area was constructed, based on data about individuals, locations, and activity patterns. Influenza-like illness (ILI) transmission was simulated, producing 100 years ofin silico ILI data. Six different surveillance systems were designed and developed using gathered cases …