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A Study Of Joinpoint Models For Longitudinal Data, Libo Zhou
A Study Of Joinpoint Models For Longitudinal Data, Libo Zhou
UNLV Theses, Dissertations, Professional Papers, and Capstones
In many medical studies, data are collected simultaneously on multiple biomarkers from each individual. Levels of these biomarkers are measured periodically over certain time duration, giving rise to longitudinal trajectories. The subjects under study may also be subject to dropout due to several competing causes, the likelihood of which may be affected by the levels of these biomarkers. In this dissertation, we investigate flexible Bayesian modeling of such data, taking into account any available covariate information as well as possible censoring of the drop-out times. We propose joint models for multiple biomarkers with multiple causes of dropout. Our proposed models …