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Full-Text Articles in Physics

The Evaluation Of Erk1 Dimerization Models Using Fluorescence Correlation Spectroscopy And The Development Of Analysis Algorithms For Single-Molecule Super Resolution, Fang Huang Feb 2012

The Evaluation Of Erk1 Dimerization Models Using Fluorescence Correlation Spectroscopy And The Development Of Analysis Algorithms For Single-Molecule Super Resolution, Fang Huang

Physics & Astronomy ETDs

In this dissertation, we describe three advancements in the area of fluorescence spectroscopy and microscopy. First, we have implemented Fluorescence Correlation Spectroscopy on a home-built confocal microscope. We proposed F/N analysis which stands for the ratio between average intensity and average number of moving objects in FCS as a method to detect dimerization of fluorescently tagged proteins diffusing in three dimensions. We used the technique to evaluate the dimerization hypothesis of ERK1 protein during nucleus translocation and it shows that ERK1 nucleus translocation is dimerization independent. Second, we have developed a multi-emitter analysis algorithm for single-molecule super resolution techniques that …


Comparison Of Experiment And Theory For Electron Impact Ionization Of Isoelectronic Atoms And Molecules, Hari Chaluvadi, Kate L. Nixon, Sadek M. Amami, Andrew James Murray, Don H. Madison Jan 2012

Comparison Of Experiment And Theory For Electron Impact Ionization Of Isoelectronic Atoms And Molecules, Hari Chaluvadi, Kate L. Nixon, Sadek M. Amami, Andrew James Murray, Don H. Madison

Physics Faculty Research & Creative Works

Experimental and Theoretical Triply Differential Cross sections will be presented for low energy electron impact ionization of Ne, CH4, and NH3. The collision mechanisms responsible for the various structures found in the cross sections will be discussed.


Effect Of Projectile Coherence On Atomic Fragmentation Processes, Michael Schulz, Kisra N. Egodapitiya, Sachin D. Sharma, Aaron C. Laforge, Robert Moshammer, A. A. Hasan, Don H. Madison Jan 2012

Effect Of Projectile Coherence On Atomic Fragmentation Processes, Michael Schulz, Kisra N. Egodapitiya, Sachin D. Sharma, Aaron C. Laforge, Robert Moshammer, A. A. Hasan, Don H. Madison

Physics Faculty Research & Creative Works

We demonstrate that the projectile coherence can have a major impact on atomic fragmentation processes. This has been overlooked for decades in formal scattering theory and may explain puzzling discrepancies between theoretical and experimental fully differential cross sections for single ionization.


Differential Cross Sections For Single Ionization Of H₂ By 75kev Proton Impact, Ujjal Chowdhury, Michael Schulz, Don H. Madison Jan 2012

Differential Cross Sections For Single Ionization Of H₂ By 75kev Proton Impact, Ujjal Chowdhury, Michael Schulz, Don H. Madison

Physics Faculty Research & Creative Works

We have calculated Triply differential cross sections (TDCS) and doubly differential cross sections (DDCS) for single ionization of H2 by 75 keV proton impact using the molecular 3 body distorted wave Eikonal initial state (M3DW-EIS) approach. Previously published measured DDCS-P (differential in the projectile scattering angle and integrated over the ejected electron angles) found pronounced structures at relatively large angles which were interpreted as an interference resulting from the two-centered potential of the molecule.