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Full-Text Articles in Physics
Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost
Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost
All Dissertations
In confocal single-molecule FRET experiments, the joint distribution of FRET efficiency and donor lifetime distribution can reveal underlying molecular conformational dynamics via deviation from their theoretical Forster relationship. This shift is referred to as a dynamic shift. In this study, we investigate the influence of the free energy landscape in protein conformational dynamics on the dynamic shift by simulation of the associated continuum reaction coordinate Langevin dynamics, yielding a deeper understanding of the dynamic and structural information in the joint FRET efficiency and donor lifetime distribution. We develop novel Langevin models for the dye linker dynamics, including rotational dynamics, based …
The Kepler Problem On Complex And Pseudo-Riemannian Manifolds, Michael R. Astwood
The Kepler Problem On Complex And Pseudo-Riemannian Manifolds, Michael R. Astwood
Theses and Dissertations (Comprehensive)
The motion of objects in the sky has captured the attention of scientists and mathematicians since classical times. The problem of determining their motion has been dubbed the Kepler problem, and has since been generalized into an abstract problem of dynamical systems. In particular, the question of whether a classical system produces closed and bounded orbits is of importance even to modern mathematical physics, since these systems can often be analysed by hand. The aforementioned question was originally studied by Bertrand in the context of celestial mechanics, and is therefore referred to as the Bertrand problem. We investigate the qualitative …